Self-healing and Self-organisation: new perspectives from an old traditional healthcare system

Yan Schroën

… ability to adapt and self-manage in the face of social, physical and emotional challenges

Towards a systemic definition of health and wellbeing:

An organism is a complex, dynamic, self-organizing system far from equilibrium

Dynamic Systems Theory

In studying self-organizing systems a shift in focus occurs:

From objects to relationships

From quantity to qualityMapping of patterns

of relationships

“1 manifests itself in 3”Yi Jing

1 2

3

3 = Qi

Qi

• Connection• Communication/Information• Movement

Energy

Matter

Life

Energy storage under energy flow

Upward organization

Downward causation

The I and the Oneness

Towards a systemic definition of health and wellbeing:

Health is a dynamic state in which a system is maximally open and there is an optimal exchange of information, without loosing the characteristics of the system itself.

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Vernetztes Denken in der biomedizinischen Forschung, Rainer H. Straub; 2013

Disease

Health

Trigger

Threshold to symptoms

Frequent urination

tiredness

thirst

Low backpain

Weakness of knee

Ear ringing

AttractorKidney Qi deficiency

Symptoms

Symptoms Systemtheory: Ba Gang

ZangFu

JingLuo

etc.

Syndrome

Symptoms Systemtheory: Ba Gang

ZangFu

JingLuo

etc.

Syndrome

Symptoms

DIAGNOSE

Systemtheory: Ba Gang

ZangFu

JingLuo

etc.

Syndrome

Symptoms

DIAGNOSE

Systemtheory: Ba Gang

ZangFu

JingLuo

etc.

Treatment principle

Syndrome

Symptoms

DIAGNOSE

Systemtheory: Ba Gang

ZangFu

JingLuo

etc.

Treatment principle

Treatment

How to design a intervention for a complex system?12 subtypes of Diabetes II:Biomarker fingerprinting

DMII subtype 8

DMII subtype 2

DMII subtype 5

DMII subtype 10 DMII subtype 11

DMII subtype 3

DMII subtype 6

DMII subtype 4

DMII subtype 7

DMII subtype 9

DMII subtype 12

DMII subtype 1

Diabetes II

Qi & Yin Xu Qi & Yin Xumet stagnatie

Qi & Yin Xumet

DampHitte

Spleen deficiency – Liver Qi stagnation Spleen deficiency with Damp Spleen deficiency with Blood stagnation Damp Heat and Qi stagnation Kidney and Stomach Yin deficiency Yin deficiency with rising Yang Lung Yin deficiency Liver Yin deficiency Heart Yin deficiency Qi and Yin deficiency Qi and Yin deficiency with Blood stasis Yin and Yang deficiency

Visceral adiposity

LDL elevated

Glucose toxicity

Fatty liver

gutinflammation

endothelialinflammation

systemicInsulin resistance

systemic inflammation

Vioxx

Salicylate

Atorvastatin

Fenofibrate

Metformin

Glibenclamide

LXR agonist

RosiglitazonePioglitazone

Sitagliptin

Hepatic IR

Adipose IR

Muscle metabolicinflexibility

adiposeinflammation

Microvascular damage

Myocardialinfactions

Heartfailure

Cardiacdysfunction

Braindisorders

Nephropathy

Atherosclerosis

β-cell failure

Reversible process

β-cell Pathology

High cholesterolHigh glucose

gluc Risk factor

Hypertension

dyslipidemia

ectopic lipid overload

Ìrreversible process

Hepaticinflammation

Stroke

IBD

fibrosis

Retinopathy

Metabolicallyhealthy

Physical inactivityCaloric excess

Thank You