Onderzoeksgroep: STATISTIEK A Identiteit van de ... · PDF fileOnderzoeksgroep: STATISTIEK A...

Onderzoeksgroep: STATISTIEK

A Identiteit van de deelnemende onderzoekers

Aerts Marc, Alonso Ariel, Beunckens Caroline, Bijnens Luc, Bollaerts Kaatje, Braekers Roel,

Bruckers Liesbeth, Burzykowski Tomasz, Buyse Marc, Callaert Herman, Callaert Kris, Cortiñas

Abrahantes José, Creemers An, Duchateau Luc, Faes Christel, Gaddah Auguste, Geys Helena,

Lin Dan, Haldermans Philippe, Hens Niel, Jacobs Tom, Jansen Ivy, Janssen Paul, Kadankova

Tetyana, Kasim Adetayo, Laenen Annouschka, Lesaffre Emmanuel, Litière Saskia, Maringwa

John, Massonnet Goele, Mattiacci Maria Rosa, Molenberghs Geert, Namata Harriet, Pryseley

Assam Nkouibert, Qi Zhu, Renard Didier, Serroyen Jan, Shkedy Ziv, Sotto Cristina, Thijs

Herbert, Tibaldi Fabian, Tilahun Eshete Abel, Valkenborg Dirk, Vandersmissen Veerle, Van

Effelterre Thierry, Van Sanden Suzy, Van Steen Kristel, Veraverbeke Noël, Verbeke Geert,

Weyler Joost, Winters Bart, Wouters Kristien, Wouters Luc.

B Titel(s) van het (de) onderzoeksproject(en)

a. Mathematische statistiek

b. Biostatistiek

C Beschrijving van de ontwikkelde onderzoeksactiviteit(en) per project

- Research on statistical education (HC)

- Resampling methods (NV, PJ, Jan Swanepoel)

- Kernel estimators with reduced bias (NV, PJ, Jan Swanepoel)

- Relative hazard rate estimation for censored and left truncated data (NV, PJ, Ricardo Cao,

Elisa Molanes)

- Conditional mean and median residual life (NV)

- Quantiles under dependent censoring (NV)

- Weak convergence for copulas with covariates (NV)

- Goodness-of-fit for relative hazard (NV, Elisa Molanes)

- Bayes and empirical Bayes estimators (NV, Lichun Wang)

- Application of exit problems for Lévy processes in financial mathematics (TK, NV, Jasper

Anderluch)

- Weak convergence representation of the conditional Koziol-Green model under dependent

censoring (RB, AG, NV)

- Nonparametric estimation of the conditional distribution function in a mixture Koziol- Green

model under dependent censoring (RB, AG)

- Heteroscedastic regression model with dependency between error and covariate (RB, Ingrid

Van Keilegom)

- Modeling the proportion of bullets that pass through a bullet proof vest (RB, M.Bijvank, M.C.

Bramati, L. Mohammandi, F. Rigat, P. van de Ven, T. Kadankova, S. Anisov, A. Schaap)

- Analysis of microarray data: dose-response analysis, identification of biomarker genes and

normalization of cDNA microarrays with linear mixed models (ZS)

Modeling infectious diseases data: joint and univariate flexible modeling (ZS)

- Fitting frailty models via linear mixed models using model transformation (GMa, PJ, TB)

- Two-stage estimation in copula models: methodology, example and simulations (GMa, PJ,

Luc Duchateau)

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- Frailty models (PJ, Luc Duchateau)

- Frailty models versus copula models (PJ, Luc Duchateau, Klaartje Goethals)

- The choice of the frailty density: diagnostics, a simulation study (PJ, GMa, Luc Duchateau)

- Goodness-of-fit (for frailty models, for censored data) (PJ, NV, GMa, Jan Swanepoel, Luc

Duchateau)

- Validation of prognostic indices using the frailty model (PJ, Catherine Legrand, Richard

Sylvester, Luc Duchateau)

- Missing data and sensitivity analysis (GM, MA, HT, IJ, CB, CS, AC, Geert Verbeke, Dimitris

Rizopoulos, Sypridoula Tsonaka, Kristel Van Steen, Els Goetghebeur, Michael G. Kenward,

Stijn Vansteelandt)

- Missing data in clinical trials (GM, Michael G. Kenward, Raymond J. Carroll, Craig

Mallinckrodt, CB, IJ, CS)

- Pattern-mixed models (GM, HT, Michael G. Kenward, CB, IJ)

- Surrogate markers (GM, TB, HG, FT, JC, AA, ZS, Tony Vangeneugden, Didier Renard, AT, PA)

- Neuron synchronization (Carmen Cadarso, HG, GM, AA, CF)

- Logistic mixed models in item response theory (GM, Geert Verbeke, Paul De Boeck, Dirk

Smits, Edward Ip, Yuri Goegebeur)

- Models for discrete repeated measures (GM, Geert Verbeke)

- Small-sample degrees for freedom (GM, CF, Geert Verbeke, Michael G. Kenward)

- Methods for clustered data (MA, HG, CF, GM)

- Models for infectious diseases (MA, ZS, GM, NH)

- Methods for optimization in statistics (GM, Geert Verbeke, Iven Van Mechelen, Francis

Tuerlinckx)

- Psychometric methods in clinical studies (GM, AL, AA, Tony Vangeneugden)

- Modeling infectious diseases (MA, ZS, GM, CF, NH, JC, KB, HN, Pierre Van Damme, Philippe

Beutels, Heidi Theeten, Koen Van Herck, Frank Boelaert, Koen Mintiens, Stefan Roels, Dirk

Berkvens, Patrick Cras, Claude Saegerman, Peter Teunis en Jacco Wallinga)

- Microbioal risk assessment and food safety (MA, ZS, CF, JC, KB, HN, Koens Mintiens, Ides

Boone, Yves Van der Stede, Stefan Roels, Stefaan Ribbens, Jeroen Dewulf, Koen Grijspeerd,

Peter Teunis)

- Methods of the analysis of microrray data (TB, SV, DL, ZS)

- Methods of the analysis of proteomics data (TB, DV)

- Bootstrap for multivariate failure-time data (TB, GMa, PJ)

- Validation of surrogate endpoints in multiple randomized clinical trials (TB, PJ, Marc Buyse)

- Meta-analysis of clinical trials (TB, Marc Buyse)

- Modelling prevalence and force of infection on serological data (NH, MA, ZS, Nigel Gay, John

Edmunds)

- Infant vaccination coverage in 2005 and predictive factors for incomplete or invalid

vaccination in Flanders, Belgium: an EPI survey (NH, MA, Heidi Theeten, Pierre Van Damme,

Philip Beutels, Corinne Vandermeulen, Mathieu Roelants, Karel Hoppenbrouwers, Anne-Marie

Depoortere)

- Who mixes with who ? Analyzing contact data. (NH, MA, ZS, Polymod working group)

- The EM algorithm by the method of weights (NH, Kennedy Otwombe)

- The MAR-bodyguard for the shared parameter model: a nonparametric alternative to

weighted estimating equations under MAR (NH, AC, MA, GM)

- Model selection based on presmoothing (NH, MA, Jeff Simonoff)

- Model selection for incomplete and design-based samples (NH, MA, GM)

- The Receiver Operator Characteristic curve (NH, MA, Kostas Fokianos)

- Model selection (MA, NH, Jeffrey Simonoff)

- Missing data (MA, GM, HT, NH, IJ, AC, Geert Verbeke, Michael G. Kenward)

Jaarverslag Onderzoeksgroepen 2006

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- Mixed models (MA, GM, JS, Geert Verbeke)

- Medical diagnostic testing (MA, NH, Kostas Fokianos, Frank Buntinx)

- Use of historical data (MA, CF, JM, HG)

- Degrees of freedom approximation and effective sample size (CF, MA, GM)

- Model averaging in toxicology and microbial risk assessment (CF, MA, HN)

- Effect of clustering and missingness on the force of infection (CF, NH, MA)

- Joint modeling of discrete and continuous longitudinal endpoints (CF, MA, HG)

- Spatial epidemiology (CF)

- Semiparametric mixed models (CF, JM, ZS)

- Analysis of juvenile toxicity studies (CF, MA, HG)

- Classification of psychotropic drugs based on sleep-waking behaviour data. Spline models,

with a mixed effects formulation. Fractional polynomial models with random effects.

Supervised ans unsupervised learning analysis. Linear, flexible and mixture discriminant

analysis. Neural networks, support vector machine, classification and regression trees,

bagging, random forest and boosting methods (JC)

- Psychotropic drug classification based on sleep-waking behavior of rats. Fractional

polynomial mixed models and random spline models to model the irregular longitudinal

profiles of the rats. Linear non-parametric and flexible discriminant analysis for classification.

Model Averaging for linear discriminant analysis (KW, JC, GM)

- Modelling prevalence and force of infection on case notification and serological data (KB, MA,

ZS, NH, CF, Frank Boelaert)

- Ontwikkeling van een methodologie voor de kwantitatieve beoordeling van zonotische risico’s

toegepast op het model Salmonella bij varkens (KB, MA, ZS, George Daube, Lieven De

Zutter, Koen Grijspeerdt, Koen Mintiens)

- P-splines regression with shape contraints (KB, MA, Paul Eilers)

- Bioinformatics: significance analysis of microarrays, sequence alignment, hidden Markov

models, gene-pathway findings, proteomics, mass-spectrometry data (IJ, TB, DL, DV, QZ, N.

Kwasnikowska, K. Koch, J. Van Den Bussche, F. Neven)

- Flexible modeling of serial correlation in mixed-effects models (JS, GM)

- Discriminant analysis based on longitudinal profiles (JS, GM)

- Model averaging in microbial risk assessments (HN, MA, ZS, CF)

- Microbial risk assessment and food safety: risk factors for salmonella infection bases on data

in laying hens in Belgium (HN, MA, ZS, CF)

- Estimation of the force of infection for parvo-virus B19 from prevalence data using penalized

splines model (HN, MA, ZS, CF)

- Normalization of microarrays. Connection dose-response data and microarrays (PH, ZS, SV)

- Biomarker discovery from COFRADIC data: deconvolution and feature extraction for mass

spectral serum profiles (DV, TB)

- Monoisotopic peak validation using a Poisson approximation in a combined fractional

diagonal chromatography and mass spectrometry setting (DV, TB, PA)

- A new method for rapid screening of MALDI-TOF spectra of post-translational modifications

(DV, TB, IJ)

- Label-free quantitative proteomics (DV, TB, Jean-Paul Noben)

- The EM-algorithm for correcting sequencing errors of Serial Analysis of Gene Expression data

(DV, TB, PH)

- Assessing the global normalization assumption of Escheria coli cDNA micro-arrays (DV,

Kristof Engelen)

- Significance analysis of microarray (DL, ZS, TB, H.W.H. Göhlmann, An De Bondt, Tim Perera,

Tamara Geerts, Luc Bijnens)


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- Testing for trend and classification of trends in dose-response microarray experiments (DL,

ZS, Dani Yekutieli, TB, H.W.H. Göhlmann, A. De Bondt, Tim Perera, Tamara Geerts, Ilse Van

den Wijngaert, Luc Bijnens)

- Analysis of microarray data: simulation models, classification methods, gene selection

methods, biomarkers, analysis based on Laplace distribution (SV, DL)

- Surrogate markers (AA, GM, AT, PA)

- Statistical validation of rating scales (AA, AL, GM, Tony Vangeneugden, AT, PA)

- Maximum likelihood inference under misspecification (AA, SL, GM)

- Simulation study comparing weighted estimating equations with multiple imputation based

estimating equations for longitudinal binary data (CS, GM, CB)

- Every missing not at random model has got a missing at random bodyguard (CS, GM, CB,

Michael G. Kenward)

- Case study on missing data models for Slovenian Plebiscite (CS, GM, CB)

- Meaningful parametrization for missing data models (CS, GM, Geert Verbeke)

- Reliability estimation in clinical trial data with repeated measurements (AL, AA, GM, Tony

Vangeneugden)

- Minimal Psychiatric Data: development of a new registration instrument (AL, LB, GM)

- Long-stay patients in psychiatry (AL, LB)

- Registration in institutions for Sheltered Living in Limburg (AL)

- Attitudes toward jobs in youngsters (AL)

- Incomplete longitudinal data (CB, CS)

- Project Microsensus 2006 (Agora-project) (VV)

- Enquête Federale Politie. NOTESUMO-project (VV)

- Multiple imputatie gezondheidsenquête (VV)

- Nonlinear mixed effects modeling. IVIVC modeling (TJ, GM, A. Dunne, R. Straetemans)

- Psychiatric epidemiology (LB, GM, JS)

- Analyses for SPIL-RPL (Samenwerking Psychiatrische Initiatieven Limburg – Registratie

Project Limburg) (LB, GM, JS)

- Flexible modeling, smoothing longitudinal data, penalized splines, simultaneous confidence

intervals for penalized splines, historical controls, crossover designs (JM)

D Mededelingen van resultaten van het onderzoekswerk

1 Doctoraats- en aggregaatsthesissen

11 In de onderzoeksgroep behaalde doctoraten

12 (Co)promoties van doctoraten, niet behaald aan de UHasselt

13 Lidmaatschappen van jury's van buitenlandse doctoraten

Noël Veraverbeke

20 juni 2006. Universiteit Wageningen, Nederland. Jurylid voor Pravesh Debba. “Sampling

scheme optimization from hyperspectral data” (promotor: Alfred Stein)

Geert Molenberghs


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12 oktober 2006. Université Rennes 1, France. Jurylid voor Véronique Sebille.

Habilitation thesis. (promotor: Jean-Louis Auget)

Tomasz Burzykowski

25 januari 2006. Erasmus Universiteit, Rotterdam, Nederland. Jurylid voor Laurence

Colette. “Prostate cancer: prognostic factors, markers of outcome and design of clinical

trials” (promotor: F.H. Schröder)

14 Lidmaatschappen van jury's van binnenlandse doctoraten

Geert Molenberghs

15 september 2006. Katholieke Universiteit Leuven. Jurylid voor Steffen Fieuws. "Mixed

models for multivariate longitudinal data" (promotor: Geert Verbeke)

Oktober 2006. Katholieke Universiteit Leuven. Jurylid voor Samuel Musili Mwalili.

“Bayesian and frequentist approaches to correct for misclassification error with

applications to caries research”. (promotor: Emmanuel Lesaffre)

Paul Janssen

22 mei 2006. Katholieke Universiteit Leuven. Jurylid voor Arnost Komárek. “Accelerated

failure time models for multivariate doubly-interval-censored data with flexible

distributional assumptions” (promotor: Emmanuel Lesaffre)

2 Wetenschappelijke publicaties

Internationale wetenschappelijke publicaties

20 Gepubliceerde artikels in internationale tijdschriften (opgenomen in de JCR1 of

in een door de Onderzoeksraad erkende alternatieve tijdschriftenlijst)

Wang, L. and Veraverbeke, N. (2006). Empirical likelihood in a semi-parametric model for

missing response data. Communications in Statistics-Theory and Methods, 35, 625-639.

Veraverbeke, N. (2006). Regression quantiles under dependent censoring. Statistics, 40, 117-

128.

Janssen, P., Swanepoel, J. and Veraverbeke, N. (2006). Modifying the kernel distribution

function estimator towards reduced bias. Statistics, 40, 000-000.

Wang, L. and Veraverbeke, N. (2006). Bayes prediction based on right censored data.

Statistical Papers, 00, 000-000. (electronically available at DO 10.1007/s00362-006-

0044-1)

Massonnet, G., Burzykowski, T., Janssen, P. (2006). Resampling plans for frailty models.

Communications in Statistics - Simulation and Computation, 35, 497-514.

==============================================1 JCR : Journal Citation Reports (als afzonderlijke publicatie van de Science Citation Index en van de Social Sciences Citation Index, opgemaakt door het Institute for Scientific Information).


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Legrand, C., Duchateau, L., Sylvester, R., Janssen, P., van der Hage, J., van de Velde, C. and

Therasse, P. (2006). Heterogeneity in disease free survival between centers: lessons

learned from an EORTC early breast cancer trial. Clinical Trials, 3, 1-9.

Cortiñas Abrahantes, J., Legrand, C., Burzykowski, T., Janssen, P., Ducrocq, V. and

Duchateau, L.. (2006). Comparison of different estimation procedures for proportional

hazards model with random effect. Computational statistics and Data Analysis, 00, 000-

000. (doi 10.1016/j.csda.2006.03.009).

Mathei, C., Shkedy, Z., Denis, B., Kabali, C., Aerts, M., Molenberghs, G., Van Damme, P. and

Buntinx, F. (2006). Evidence for a substantial role of sharing of injection paraphernalia

other than syringes/needles to the spread of hepatitis C among injecting drug users.

Journal of Viral Hepatitis, 00, 000-000.

Laenen, A., Vangeneugden, T., Geys, H. and Molenberghs, G. (2006). Generalized reliability

estimation using repeated measurements. British Journal of Mathematical and Statistical

Psychology, 59, 113-131.

Molenberghs, G. (2006). Book Review of Fitzmaurice, G.M., Laird, N.M., and Ware, J.H.

(2005). Applied Longitudinal Data Analysis. Journal of American Statistical Association,

00, 000-000.

Vansteelandt, S., Goetghebeur, E., Kenward, M.G. and Molenberghs, G. (2006). Ignorance and

uncertainty regions as inferential tools in a sensitivity analysis. Statistica Sinica, 16, 953-

979.

Ombelet, W., Martens, G., De Sutter, P., Gerris, J., Bosmans, E., Ruyssinck, G., Defoort, P.,

Molenberghs, G. and Gyselaers, W. (2006). Perinatal outcome of 12,021 singleton and

3,108 twin births after non-IVF assisted reproduction: a cohort study. Human

Reproduction, 21, 1025-1032.

Jansen, I., Hens, N., Molenberghs, G., Aerts, M., Verbeke, G. and Kenward, M.G. (2006). The

nature of sensitivity in missing not at random models. Computational Statistics and Data

Analysis, 50, 830-858.

Shkedy, Z., Aerts, M., Molenberghs, G., Beutels, P. and Van Damme, P. (2006). Modelling

age-dependent force of infection from prevalence data using fractional polynomials.

Statistics in Medicine, 25, 1577-1591.

Jansen, I., Beunckens, C., Molenberghs, G., Verbeke, G. and Mallinckrodt, C. (2006).

Analyzing incomplete discrete longitudinal clinical trial data. Statistical Science, 21, 52-

69.

Jansen, I., Van den Troost, A., Molenberghs, G., Vermulst, A. and Gerris, J. (2006). Modeling

partially incomplete marital satisfaction data. Sociological Methods & Research, 35, 113-

136.

Vandenbroeck, P., Wouters, L., Molenberghs, G., Van Gestel, J. and Bijnens, L. (2006).

Teaching statistical thinking to life scientists - A case-based approach. Journal of

Biopharmaceutical Statistics, 16, 61-75.

Faes, C., Geys, H., Aerts, M. and Molenberghs, G. (2006). A hierarchical modeling approach

for risk assessment in developmental toxicity studies. Computational Statistics and Data

Analysis, 51, 1848-1861.

Speybroeck, N., Marcotty, T., Aerts, M., Dolan, T., Williams, B., Lauer, J., Molenberghs, G.,

Burzykowski, T., Mulumba, M. and Berkvens, D. (2006). Titrating Theileria parva: single

stocks against combination of stocks. International Journal for Parasitology, 00, 000-000.

Hens, N., Aerts, M. and Molenberghs, G. (2006). Model selection for incomplete and design-

based samples. Statistics in Medicine, 25, 2505-2520.

Alonso, A., Geys, H., Molenberghs, G. (2006). A unifying approach for surrogate marker

validation based on Prentice's criteria. Statistics in Medicine, 25, 205-221.


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Cadarso-Suárez, C., Roca-Paradiñas, J., Molenberghs, G., Faes, C., Nácher, V., Ojeda, S. and

Acuña, C. (2006). Flexible modeling of neuron firing rates across different experimental

conditions: an application to neural activity in the prefrontal cortex during a

discriminating task. Applied Statistics, 55, 431-447.

Molenberghs, G. and Verbeke, G. (2006). The Diggle-Kenward model for dropout.

Encyclopedia of Measurement and Statistics, 000-000.

Molenberghs, G. (2006). Viewpoint: Biometry and Biometrics. Sensor Review, 26, 5-6.

Tibaldi, F., Verbeke, G., Molenberghs, G., Renaerd, D., Van den Noortgate, W. and De Boeck,

P. (2006). Conditional mixed models with crossed-random effects. British Journal of

Mathematical and Statistical Psychology, 00, 000-000.

Aelvoet, W., Vanoverloop, J., Molenberghs, G., Schoeters, G., van Sprundel, M. and Vlietinck,

B. (2006). Routineley collected data to assess reproductive health in a community around

two household refuse incinerators. Archives of Public Health, 00, 000-000.

Van Sanden, S., Wouters, L., Burzykowski, T., Molenberghs, G., Van Remoortere, M., Meert,

T. and Bijnens, L. (2006). A modelling approach to the analysis of nerve regenerative

experiments. Journal of Biopharmaceutical Statistics, 16, 843-859.

Goegebeur, Y., De Boeck, P., Molenberghs, G. and del Pino, G. (2006). A local-influence-based

diagnostic approach to a speeded item response theory model. Applied Statistics, 55,

647-676.

Alonso, A. and Molenberghs, G. (2006). Surrogate marker evaluation from a information

theoretic perspective. Biometrics, 00, 000-000.

Shen, S., Beunckens, C., Mallinckrodt, C. and Molenberghs, G. (2006). A local influence

sensitivity analysis for incomplete longitudinal depression data. Journal of

Biopharmaceutical Statistics, 16, 365-384.

Mallinckrodt, C.H., Detke, M.J., Kaiser, C.J., Watkin, J.G., Molenberghs, G. and Carroll, R.J.

(2006). Comparing onset of antidepressant action using a repeated measures approach

and a traditional assessment schedule. Statistics in Medicine, 25, 2384-2397.

Faes, C., Aerts, M., Geys, H. and Molenberghs, G. (2006). Model averaging using fractional

polynomials to estimate a safe level of exposure. Risk Analysis, 00, 000-000.

Molenberghs, G. and Verbeke, G. (2006). Likelihood ratio, score, and Wald tests in a

constrained parameter space. The American Statistician, 00, 000-000.

Van Steen, K., Laird, N.M., Markel, P. and Molenberghs, G. (2006). Approaches to handle

incomplete data in family-based association testing. Annals of Human Genetics, 00, 000-

000.

Molenberghs, G., Vangeneugden, T. and Laenen, A. (2006). Estimating reliability and

generalizability from hierarchical biomedical data. Journal of Biopharmaceutical Statistics,

00, 000-000.

Beunckens, C., Molenberghs, G., Thijs, H. and Verbeke, G. (2006). Incomplete hierarchical

data. Statistical Methods in Medical Research, 00, 000-000.

Fieuws, S., Verbeke, G. and Molenberghs, G. (2006). Random-effects models for multivariate

repeated measures. Statistical Methods in Medical Research, 00, 000-000.

Litière, S., Alonso, A. and Molenberghs, G. (2006). Tuype I and type II error random-efects

misspecification in generalized linear mixed models. Biometrics, 00, 000-000.

Alonso, A., Molenberghs. G., Burzykowski, T., Renard, D., Geys, H., Shkedy, Z., Tibaldi, F.,

Cortiñas Abrahantes, J. and Buyse, M. (2006). Response to "Qu and Case's Letter about

'Prentice's approach and the meta-analytic paradigm: a reflection on the role of statistics

in the evaluation of surrogate endpoints' (Biometrics, 60, 724-728)" . Biometrics, 00,

000-000.

Molenberghs, G. and Verbeke, G. (2006). Discussion of Lee, Y. and Nelder, J.A.: "Double

hierarchical generalized linear models," Applied Statistics, 00, 000-000.


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Molenberghs, G. and Verbeke, G. (2006). Discussion of Lee, Y. and Nelder, J.A.: Likelihood for

random-effect models," Sort, 29, 000-000.

Laenen, A., Bruckers, L., Goossens, M., Houben, L. and Molenberghs, G. (2006). Wachttijden

in de CGG onderzocht. Acta Hosptalia, 00, 000-000.

Jansen, I. and Molenberghs, G. (2006). A flexible marginal modeling strategy for non-

monotone missing data. Journal of the American Statistical Association, 00, 000-000.

Thijssen, S., Maringwa, J., Faes, C., Lambrichts, I. and Van Kerkhove, E. (2007). Chronic

exposure of mice to environmentally relevant, low doses of cadmium leads to early renal

damage, not predicted by blood or urine cadmium levels. Toxicology 229, 145-156.

Vanderlocht, J., Burzykowski, T., Somers, V., Hellings, N. (2006). No association of leukemia

inhibitory factor (LIF) DNA polymorphisms with multiple scleroris. Journal of

Neuroimmunology, 171, 189-192.

Collette, L., Burzykowski, T., Schröder, F.H. (2006). Prostate-specific antigen (PSA) alone is

not an appropriate marker of long term therapeutic benefit in prostate cander trials.

European Journal of Cancer, 42, 1344-1350.

Burzykowski, T., Buyse, M. (2006). Surrogate threshold effect: An alternative measure for

meta-analytic surrogate endpoint validation. Pharmaceutical Statistics, 5, 173-186.

Glick, I.D., Shkedy, Z., Schreiner, A. (2006). Differential early onset of therapeutic response

with risperidone vs conventional antipsychotics in patients with chronic schizophrenia.

International Clinical Psychoparmacology, 21, 261-266.

Beutels, P., Shkedy, Z., Aerts, M., van Damme, P. (2006). Social mixing patterns for

transmission models of close contact infections: exploring self-evaluation and diary-based

data collection through a web-based interface. Epidemiology and infection. - (doi:

10.1017/S0950268806006418).

Faes, C., Aerts, M., Geys, H., Bijnens, L., Lammers, W. (2006). General mixed-model

framework for modelling correlated categorical data. Analysis of spike train in intestine of

a cat. Statistical Modeling, 6, 1-21.

Faes, C., Hens, N., Aerts, M., Shkedy, Z., Geys, H., Mintiens, K., Laevens, H. and Boelaert, F.

(2006). Random-effects models for clustered binary data using monotone fractional

polynomials; with application to the estimation of a herd-specific force of infection.

Applied Statistics, 55, 595-613.

Van den Bruel, A., Aertgeerts, B., Bruyninckx, R., Aerts, M. and Buntinx, F. (2006). Signs and

symptoms for the diagnosis of serious infections in children: a prospective study in

primary care. British Journal of General Practics, 00, 000-000.

Bollaerts, K., Eilers, P.H.C. and Aerts, M. (2006). Quantile regression with monotonicity

restrictions using P-splines and the L1-norm. Statistical Modelling, 6, 189-207.

Bollaerts, K., Eilers, P., Van Mechelen, I. (2006) "Simple and multiple P-splines regression

with shape constraints." British Journal of Mathematical and Statistical Psychology, 59,

451-496.

Van Sanden, S., Lin, D., Burzykowski, T. (2006). Performance of classification methods in a

microarray setting: a simulation study. Biocybernetics and Bioengineering, 000-000.

Chen, L., Geys, H., Cawthraw, S., Havelaar, A. and Teunis, P. (2006). Dose response for

infectivity of several strains of Campylobacter jejuni in chickens. Risk analysis, 00, 000-

000.

Wouters, K., Ahnaou, A., Cortiñas, J., Molenberghs, G., Geys, H., Bijnens, L. and Drinkenburg,

W.H.I.M., (2006). Psychotropic drug classification based on sleep wake behaviour of rats.

Applied Statistics, 00, 000-000.

Vandenhove, H., Van Hees, M., Wouters, K. and Wannijn, J. (2006). Can we predict uranium

bioavailability based on sail parameters ? Part 1: Effect of soil parameters on soil solution

uranium concentration. Environmental Pollution, 00, 000-000.


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Vandenhove, H., Van Hees, M., Wouters, K. and Wannijn, J. (2006). Can we predict uranium

bioavailability based on sail parameters ? Part 2: Soil solution uranium concentration is

not a good bioavailability index. Environmental Pollution, 00, 000-000.

Beersmans, S., Muys, J., Van Beurden, A., Vidakovic, M., Weyler, J., Thijs, H., Rodrigus, I.

and Bossaert, L. (2006). Are the current tools for assessing the quality of life after cardiac

arrest valid. Resuscitation, 69, 1-37.

Rafter. J., Bennett, M., Caderni, G., Clune, Y., Hughes, R., Karlsson, P.C., Klinder, A.,

O'Riordan, M., O'Sullivan, G.C., Pool-Zobel, B., Rechkemmer, G., Roller, M., Rowland, I.,

Salvadori, M., Thijs, H., Van Loo, J., Watzl, B. and Collins, J.K. (2006). Dietary synbiotic

reduces cander risk factors in polypectomised and colon cancer patients. The American

Journal of Clinical Nutrition, 00, 000-000.

Robaeys, G., Van Vlierberghs, H., Mathei, C., Van Ranst, M., Bruckers, L., Buntinx, F. (2006).

Similar compliance and effect of treatment in chronic hepatitis C resulting from

intravenous drug use in comparison with other infection cause. European Journal of

Gastroenterology & Hepathology, 18, 159-166.

Tournigand, C., Cervantes, A., Figer, A., Lledo, G., Flesh, M., Buyse, M., Mineur, L., Carola, E.,

Etienne, P.L., Rivera, F., Chirivella, I., Perez-Staub, N., Louvet, C., André, T., Tabah-

Fisch, I., de Gramont, A. (2006). FOLFOX4 or FOLOFOX7 with oxaliplatin stop-and-go in

advanced colorectal cancer. Optimox1, a randomized GERCOR study. Journal Clinical

Oncology. 24, 394-400.

Glynn-Jones, R., Mawdsley, S., Pearce, T., Buyse, M. (2006). Alternative clinical end points in

rectal cancer - are we getting closer ? Annals Oncology, 17, 1239-1348.

André, T., Sargent, D., Tabernero, J., O'Connell, M., Buyse, M., Sobrero, A., Misset, J.L., Boni,

C., Vanhoeffer, U., de Gramont, A. (2006). Current issues in adjuvant traetment of stage

II colon cancer. Annals Surgical Oncology. 13, 887-898.

Fieuws, S. and Verbeke, G. (2006). Pairwise fitting of mixed models for the joint modelling of

multivariate longitudinal profiles. Biometrics, 62, 424-431.

Fieuws, S., Verbeke, G., Boen, F. and Delecluse, C. (2006). High dimensional multivariate

mixed models for binary questionnaire data. Applied Statistics, 55, 449-460.

Tuerlinckx, F., Rijmen, F., Verbeke, G. and De Boeck, P. (2006). Statistical inference in

generalised linear mixed models: a review. British Journal of Mathematical and Statistical

Psychology, 59, 225-255.

Hoflack, G., Opsomer, G., Van Soom, A., Maes, D., de Kruif, A., Duchateau, L. (2006).

Comparison of sperm quality of Belgian Bleu and Holstein Friesian bulls. Theriogenology

66, 1834-1846.

Hellemans, A., Decostere, A., Duchateau, L., De Bock, M., Haesebrouck, F., Ducatelle, R.

(2006). Protective immunization against "Candidatus Helicobacter suis" with heterologous

antigens of H. pylori and H. felis. Vaccine 24, 2469-2476.

Hoflack, G., Van Soom, A., de Kruif, A., Opsomer, G., Duchateau, L. (2006). Breeding

soundness and libido examination of Belgian Bleu and Holstein Friesian artificial

insemination bulls in Belgium and The Netherlands. Theriogenology 66, 207-216.

Verbeke, G., Fieuws, S., Lesaffre, E., Kato, B.S., Foreman, M.D., Broos, P.L.O. and Milisen, K.

(2006). A comparison of procedures to correct the baseline differences in the analysis of

continuous longitudinal data: a case study. Applied Statistics, 55, 92-101.

Küchenhoff, A., Mwalili, S.M., Lesaffre, E. (2006). A general method for dealing with

misclassificaton in regression: the misclassification SIMEX. Biometrics, 62, 85-96.

Vrijens, B., Belmans, A., Matthys, K., De Klerk, E. and Lesaffre, E. (2006). Effect of patient

intervention and compliance-enhancing pharmaceutical care on adherence with

Atorvastatin. Pharmacoepidemiology & Drug Safety, 15, 115-121.


10.

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Overige wetenschappelijke publicaties

25 Overige artikels

- Veraverbeke, N. (2006). De Belgische Vereniging voor Statistiek. STAtOR 7, 26-27.

- Shkedy, Z., Aerts, M., and Callaert, H. (2006). The weight of Euro coins: its distribution

might not be as normal as you would expect. Journal of Statistics Education Volume 14,

Number 2 [e-journal: www.amstat.org/publications/jse/v14n2].

26 Artikels in proceedings

- Veraverbeke, N. (2006). Nonparametric estimation problems under dependent

censoring. In: A collection of papers on the 50th anniversary of the department.

Technical Report nr. 365, University of the Free State, Bloemfontein, South Africa, pp.

89-100.

- Kadankova, T.V. and Veraverbeke, N. (2006). Several two-boundary problems for Lévy

processes. Proceedings of the 4th Actuarial and Financial Mathematics Day. Ed A. De

Schepper et al. KVAB, Brussel, pp. 97-106. (D/2006/0455/20)

- Litière, S., Alonso, A., Molenberghs, G. (2006). Type I and Type II error under random-

effects misspecification in generalized linear mixed models. Proceedings of the 23rd

Internation Biometric Conference. Montréal, Québec – Canada, July 16-21, 2006.

- Alonso, A., Molenberghs, G. (2006). Surrogate marker validation from an information

theory perspective. Proceedings of ENAR, Tampa.

- Laenen, A., Alonso, A., Molenberghs, G. (2006). A measure for the reliability of a rating

scale based on longitudinal clinical trial data. Proceedings of the 23rd International

Biometric Conference. Montréal, Québec – Canada, July 16-21, 2006.

- Bijvank, M., Bramati, M.C., Mohammadi, L., Rigat, P., van de Ven, R., Braekers, R.,

Kadankova, T., Anisov, A. (2006). Bullet Proof Math: “Modeling the proportion of bullets

that pass through the vest”. Proceedings of the 55th European Study Group,

Mathematics with Industry. T.U.Eindhoven, pp. 25-50.

- Maringwa, J.T., Geys, H., Shkedy, Z., Faes, C., Molenberhgs, G., Aerts, M., Van Ammel,

K., Teisman, A. and Bijnens, L. (2006). Analysis of a cardiovascular safety experiment

with longitudinal data using penalized splines. Proceedings of the 21st International

Workshop on Statistical Modelling. Hinde, J., Einbeck, J. and Newell, J. (Eds.), Galway,

Ireland, pp. 346-353.

- Aerts, M., Bollaerts, K., Hens, N., Shkedy, Z., Van Damme, P. and Beutels, P. (2006).

Estimating the force of infection directly from antibody levels. Proceedings of the

International Conference on Statistical Latent Variables Models in the Health Sciences,

Perugia, Italy.

- Faes, C. (2006). Correcting for model uncertainty when using fractional polynomials to

estimate a safe level of exposure. Proceedings of the 23rd International Biometric

Conference. Montréal, Québec, Canada, July 16- 21, 2006.

- Hens, N., Aerts, M., Shkedy, Z., Van Damme, P. and Beutels, P. (2006). Flexible

bivariate modelling of serological data. Proceedings of the 23rd International Biometric

Conference, Montréal, Québec, Canada, July 16-21, 2006.

- Vyt, P., Maes, D., Quinten, C., Aerts, M., Rijsselaere, T., Deley, T., Van Soom, A.

(2006). Predictive value of sperm motility characteristics and morphology on

reproductive perfomance in sows. Proceedings of the 14th Annual Meeting of the Flemish


11.

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Society for Veterinary Epidemiology and Economics, 2006, Ghent, Belgium. R. Geers

and J. Vandenheede (eds.) pp. 83-86. (ISBN: 90-5864-103-1).

- Bollaerts, K., Aerts, M., Ribbens, S., de Sadeleer, L., Mintiens, K. and Boone, I. (2006).

Identification of Salmonella risk factors in pig farms. Proceedings of the 14th Annual

Meeting of the Flemish Society for Veterinary Epidemiology and Economics, 2006,

Ghent, Belgium, R. Geers and J. Vandenheede (eds.) pp. 37-40. (ISBN: 90-5864-103-1)

- Cortiñas Abrahantes, J., Wanyama, S.S., Mintiens, K., Geys, H., van Everbroeck, B.,

Cras, P., Berkvens, D., Saegerman, C., Roels, S. and Aerts, M. (2006). Statistical

analysis of bovine spongiform encephalopathy data in Belgium. Proceedings of the 11th

International Symposium on Veterinary Epidemiology and Economics, 2006. Cairns,

Australia, pp. 594-598. (ISSN: 1177-3618)

- Namata, H., Aerts, M., Faes, C. and Mintiens, K. (2006). Risk factor identification of

Salmonella for layer chicken in Belgium. In: Proceedings of the 11th International

Symposium on Veterinary Epidemiology and Economcs, 2006, Cairns, Australia. 3

pages. (ISSN: 1177-3618)

- Massonnet, G., Janssen, P., Burzykowski, T. (2006). Fitting frailty models via linear

mixed models using model transformation. Proceedings of the International Conference

on Statistical Methods for Biomedical and Technical Systems, Limassol, Cyprus, Ed. Filia

Vonta, pp. 387-391. (ISBN: 9963-644-53-8).

- Bollaerts, K., Aerts, M., Faes, C., Hens, N. and Boelaert, F. (2006). Modelling the force

of infection of the bovine herpesvirus-1 in Belgian cattle: a Bayesian approach to

account for test misclassification. Proceedings of the International Conference on

Statistical Latent Variables Models in the Health Sciences. Perugia, Italy.

27 Uitgaven van publicaties of proceedings als editor

- Beirlant, J., Carbonez, A., Schoutens, W., Van Assche, W. and Veraverbeke, N., (2006).

(editors) Special issue. Journal of Computational and Applied Mathematics, 186, 1-324.

28 Uitgaven van wetenschappelijke boeken

3 Congressen en voordrachten

31 Organisatie van internationale wetenschappelijke congressen of zomerschool

One-day Symposium "Multiple Comparison and False Discovery Rates", Holiday Inn Hotel,

Hasselt, 11 mei 2006.

Organisatie: Censtat

Statistics Afternoon, Universiteit Hasselt, 12 mei 2006.

Organisatie: Censtat

Workshop on “Survival Analysis”, Universiteit Hasselt, 19 mei 2006.

Organisatie: Noël Veraverbeke en P. Janssen (UHasselt) en Ingrid Van Keilegom (UCL)

57 deelnemers

QMSS Workshop (Quantitative Methods in Sociological Sciences), Universiteit Hasselt.

13-20 september 2006.

Organisatie: UHasselt en Universiteit van Southampton, U.K.


12.

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XXXIIIrd International Biometric Conference, Montréal, Québec, Canada.

16-21 juli 2006.

Organiserend voorzitter: Geert Molenberghs

32 Voordrachten op internationale wetenschappelijke congressen

Noël Veraverbeke

20-25 augustus 2006. Prague Stochastics, Praag, Tsjechische Republiek.

Residual lifetime under dependent censoring (21 augustus 2006)

Geert Molenberghs

26-29 maart 2006. Eastern Spring Meeting of the Eastern North American Region, Tampa,

Florida, U.S.A.

Models for repeated discrete data.

(26 maart 2006)


Florida, U.S.A.

Round table discussion leader on 'Incomplete Data in Longitudinal Studies'.

(27 maart 2006)

7 augustus 2006. Joint Statistical Meetings, Minneapolis, Mn, U.S.A.

Analysis of clinical trials: theory and applications.

6-10 augustus 2006. Joint Statistical Meetings, Seattle, Wa, U.S.A.

Models for repeated discrete data.

(8 augustus 2006)

6-8 september 2006. International Conference on statistical latent variable models in the

health sciences, Perugia, Italië.

A latent-variable mixture model as a basis for sensitivity analysis in incomplete

longitudinal data.

(7 september 2006)

13-21 september 2006. QMSS Workshop on Theory and Practice in the Analysis of

Longitudinal Data. Universiteit Hasselt.

Quantitative methods in the social sciences network.

13-21 september 2006. QMSS Workshop on Theory and Practice in the Analysis of

Longitudinal Data. Universteit Hasselt.

Multivariate on-sided tests in constrained parameters spaces.

(20 september 2006)

27-29 september 2006. FDA/Industry Statistics Workshop, Washington, D.C.

The statistical evaluation of surrogate endpoints in clinical trials.

(27 september 2006)


13.

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Roundtable discussion leader on 'Incomplete data in longitudinal clinical trials'.

(28 september 2006)


Development in the statistical evaluation of surrogate endpoints in clinical trials.

(28 september 2006)

Marc Aerts

13 juni 2006. Pfizer Statistics Conference, Sandwich.

Topics in close response modelling and clustered binary data.

6-8 september 2006. International Conference on statistical latent variables models in the

health science, Perugia, Italy.

Estimating the force of infection directly from antibody levels.

11-15 september 2006. Royal Statistical Society 2006 Conference, Belfast.

Flexible bivariate modelling of serological data.

Tomasz Burzykowski

27 februari 2006. Conference Phase III Clinical Trials in Oncology: from design to

approval, Amsterdam, NL.

Evaluating the use of bimarkers as surrogate endpoints.

26-29 maart 2006. ENAR Spring Meeting, Tampa, U.S.A.

Recent advances in surrogate endpoint evaluation.

16-21 juli 2006. 23rd International Biometric Conference, Montréal, Québec, Canada.

Poisson approximation based monoisotipec peak finding in COFRADIC setting.

11-14 septmber 2006. 36th International Biometrical Colloquium, Olsztyn, Poland.

Meta-analysis: why and how ?

Ziv Shkedy


Testing and evaluation of gene expression data as surrogate biomarkers in pre-clinical

experiments.

26-28 september 2006. Non-clinical statistics conference, Postdam, Germany.

Testing and evaluation of gene-expression data as surrogate biomarkers in pre-clinical

experiments.

Roel Braekers

30 januari - 3 februari 2006. 55th European Study Group, Mathematics with Industry (SWI

2006), Eindhoven, NL.

Bullet proof math.


14.

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24-28 juli 2006. 26th European Meeting of Statisticians, Torun, Poland.

A conditional Koziol-Green model under dependent censoring.

Christel Faes


Correcting for model uncertainty when using fractional polynomials to estimate a safe

level of exposure.

José Cortiñas


Florida, U.S.A.

Calissification of psychotropic drugs based on sleep-waking behaviour in rats.

5-11 augustus 2006. 11th Symposium of the International Society for Veterinary

Epidemiology and Economics. Cairns, Australia.

Statistical analysis of bovine spongiform encephalopathy data in Belgium.

Ariel Alonso

26-29 maart 2006. ENAR Meeting, Tampa, U.S.A.

Surrogate marker velidation from an information theory perpective.


Surrogate marker validation: an information theory perspective.

Oktober 2006. BDS Conference, Glaxo Smith Kline, London, U.K.

From the Prentice's approach to the meta-analytic paradigm: an overview about the

surrogate marker evaluation.

Oktober 2006. Conference on surrogate endpoints, French Statistical Society, Paris,

France.

From the Prentice's approach to the meta-analytic paradigm: an overview about the

surrogate marker evaluation.

29 november - 1 december 2006. EUFEPS Conference on Optimising Drug Development,

Basel, Switzerland.

An overview about surrogate marker evaluation.

Tetyana Kadankova

30 januari - 3 februari 2006. 55th European Study Group Mathematics with Industry

(SWI2006), Eindhoven, NL.

Bullet Proof Math

17 - 21 juli 2006. 31st Conference on Stochastic Processes and its Applications, Paris,

France.

Two-sides exit problems for general Lévy processes.


15.

=

Dan Lin

26 - 28 september. Non-clinical statistics conference, Potsdam, Germany.

Significance Analysis of Microarrays (SAM) for biomarker selection using gene expression

data (27 september 2006).

Annouschka Laenen

16 - 21 juli 2006. 23rd International Biometric Conference, Montréal, Québec, Canada.

A measure for the reliability of a rating scale based on longitudinal clinical trial data.

13 - 21 september 2006. Universiteit Hasselt.

QMSS Workshop on Theory and Practice in the Analysis of Longitudinal Data.

A measure fot the reliability of a rating scale based on longitudinal clinical trial data.

Saskia Litière


Type I and type II error under random-effects misspecification in generalized linear mixed

models.



The impact of a misspecified random-effects distribution on maximum likelihood

estimation in generalized linear mixed models.

Niel Hens


Flexible bivariate modelling of serological data.

13-21 september 2006. Universiteit Hasselt.


Kernel weighted influence measures.

Cristina Sotto



A simulation study comparing weighted estimating equations and multiple imputation

based estimating equations (20 september 2006).

Goele Massonnet

29 - 31 mei 2006. Limassol, Cyprus. Statistical Models for Biomedical and Technical

systems.

Fitting frailty models via linear mixed models using model transformation

Ivy Jansen


16.

=


QMSS Workshop on Theory and Practice in the Analysis of Longitudunal Data.

Models for longitudinal and incomplete data.

Jan Serroyen

26 - 29 maart 2006. ENAR Meeting, Tampa, U.S.A.

Signal intensity processing based on non-linear mixed modeling to study changes in

neuronal activity.

Harriet Namata

6 - 11 augustus 2006. International Symposium on veterinary epidemiology and

economics (ISVEEXI), Cairns, Australia.

Risk factor Identification of Salmonella for layer chicken in Belgium.

Caroline Beunckens

26 - 29 maart 2006. ENAR Meeting, Tampa, U.S.A.

A latent class mixture model for dealing with incomplete longitudinal data.

Tom Jacobs

6 - 8 maart 2006. 18th Annual Drug Information Association Euro Meeting 2006, Paris,

France.

The use of IVIVC in pharmaceutical research.

26 - 28 september 2006. Non-Clinical Statistics Conference, Potsdam, Duitsland.

Modelling in vivo - in vitro correlation data of a heterogeneous formulation using a

mixture of distribution.

Herbert Thijs


Issues in dealing with incomplete longitudinal data using selection models.



Sensitivity analysis for longitudinal clinical trials.

Liesbeth Bruckers


Persistent disturbing behavior: clustering longitidunal profiles.

15 december 2006. International Symposium: Synthesising Research results of the

Flemish Center of expertise for environment and health. Brussel.

Statistical methodology of guidelines for analysis.


17.

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John Maringwa

3-7 juli 2006. 21st International Workshop on Statistical Modelling. Galway, Ireland.

Analysis of a cardiovascular experiment with longitudinal data using penalized smoothing

splines.

(awarded 4th best student presentation).

33 Voordrachten in het buitenland op uitnodiging van instellingen of organisaties

Noël Veraverbeke

13 oktober 2006. University of the Free State. Bloemfontein, Zuid Afrika.

Nonparametric estimation problems under dependent censoring.

Geert Molenberghs

27 januari 2006. Glaxo Smith Kline, Harlow, U.K.

Evaluation of surrogate endpoints in randomized clinical trials.

2 februari 2006. Mc Gill University, Montréal, Canada.

Multivariate one-sided tests in constrained parameter spaces.

8 - 10 februari 2006. Erasmus Winter Programme 2005, Erasmus Medical Center,

Rotterdam, NL.

Missing values in clinical research.

23 - 24 maart 2006. Forest Research Institute, New Jersey.

Longitudinal data, mixed models and incomplete data.

30 maart 2006. Centers for Desease Control and Prevention, Atlanta, Georgia.

Models for repeated continuous, discrete, and incomplete data.

31 mei - 3 juni 2006. Universidad de Santiago de Compostela, Spain.

Longitudinal and incomplete data.

31 mei - 3 juni 2006. Universidad de Santiago de Compostela, Spain.

The applied statistical scientist in a high-profile academic environment.

14 - 15 juni 2006. Graduate Program in Statistics, University of Neuchâtel, Switzerland.

Incomplete data.

4 oktober 2006. Tilburg University, NL.

Multivariate one-sided tests in constrained parameter spaces.

18 - 19 oktober 2006. RIVM, Bilthoven, NL.


9 - 10 november 2006. University of Copenhagen, Denmark.

Incomplete data.


18.

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13 - 17 november 2006. ESALQ, Piracicaba, Saõ Paulo, Brazilië.

ESALQ Course on models for longitudinal and incomplete data.

20 - 21 november 2006. Universiteit Leiden, NL.


11 - 12 december 2006. Société Française de Statistique, Toulouse, Frankrijk.

Missing data, particularly in longitudinal studies.

Tomasz Burzykowski

20 maart 2006. Erasmus Medisch Centrum, Rotterdam, NL.

Statistical validation of surrogate endpoints in clinical trials.

Christel Faes

21 september 2006. Bijeenkomst 'Clusters van Kanker' van de Contactgroep Gezondheid

en Chemie, en de Nederlandse Vereniging voor Milieukunde, Den Bosch, NL.

Geografische verschillen in kankerincidentie in Belgisch Limburg.

Niel Hens

11 mei 2006. Health Protection Agency, London, UK.

Modelling age-time dependent incidence rates of hepatitis B and estimating the

prevalence and force of infection using generalized additive models.

16 mei 2006. Health Protection Agency, London, UK.

Joint modelling of serological data: dependence and frailties.

18 mei 2006. Polymod meeting, Pisa, Italy.

Joint modelling of serological data: dependence and frailties.

24 oktober 2006. Polymod meeting, Bielefeld, Germany.

Flexible modelling of multivariate serological data.

Goele Massonnet

26 juli 2006. North-West University, Potchefstroom, South Africa;

Resampling plans for frailty models.

31 juli 2006. University of the Free State Bloemfontein, South Africa.


3 augustus 2006. University of Stellenbosch, South Africa.


Herbert Thijs

11 oktober 2006. ISOQOL Workshop, Lissabon, Portugal.


19.

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Dealing with incomplete longitudinal data.

34 Presentatie van posters op internationale wetenschappelijke congressen

Dirk Valkenborg

2-5 april 2006. Tenth annual international conference on research in computational

molecular biology. RECOMB 2006. Venice, Italy.

Monoisotopic peak validation using a Poisson approximation in a combined fracitonal

diagonal chromatography and mass spectrometry setting.



An algorithm to process and to analyse COFRADIC data.

John Maringwa

september 2006. JNJ Joint Statistical Meetings, New Jersey, U.S.A.

Analysis of crossover designs using semiparametrics mixed models with serial correlations

within periods.

Abel Tilahun

september 2006. JNJ Joint Statistical Meetings, New Jersey, U.S.A.

Review of statistical methods for the analysis of repeatedly measured EEG data.

Philippe Haldermans



Using linear mixed models as scatterplot smoother for normalization of cDNA microarrays.

Kaatje Bollaerts

6-8 september 2006. International conference on statistical latent variables models in the

health sciences, Perugia, Italy.

Modelling the force on infection of the bovine herpesvirus - 1 in Belgian cattle: a Bayesian

approach to account for test misclassification.

4 Expert- en referee-opdrachten

41 Lidmaatschappen van editorial board van internationale tijdschriften

Noël Veraverbeke

National correspondent voor International Association for Statistical Education (IASE)

Paul Janssen


20.

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Associate editor ‘Statistica Neerlandica’ (2003- )

Geert Molenberghs

Associate editor ‘Biostatistics’ (1999- 2006)

Wiley Series in Probability and Statistics Editor(2003- )

Co-editor of Biometrics (2007-2009)

Marc Aerts

Associate editor ‘Biometrics’

Associate editor ‘Statistical Modelling’

42 Referee-opdrachten van publicaties op aanvraag van editorial board van

internationale tijdschriften

Herman Callaert

• CERME-5 (Conference of the European Society for Research in Mathematics

educaton)

Noël Veraverbeke

• Statistics and Computing

• Journal of Computational and Applied Mathematics

• Applied Statistics

• Statistics and Probability Letters (2)

• Metron

• Book (Wiley)

• Short Book Reviews (10)

• Mathematical Reviews (8)

Paul Janssen

• Statistics in Medicine (2)

• Journal of Royal Statistical Society – Series B

Geert Molenberghs

• Biostatistics (2)

• Biometrika

• Biometrics

• Applied Statistics

• Journal of the Royal Statistical Society, Series B, read paper

• Journal of the American Statistical Association

• Journal of Statistical Planning and Inference

• Canadian Journal of Statistics

• Journal of Agricultural, Biological, and Environmental Statistics

• Statistics in Medicine (2)

• Computational Statistics and Data Analysis

• Journal of Biopharmaceutical Statistics

• Statistical Methods in Medical Research

• Test

• Journal of Quality Technology

• Biostatistics (Associate Editor: 13)

• Book Proposal (Wiley, as advisor, 14)


21.

=

Niel Hens

• Statistical Modelling (2)

Tomasz Burzykowski

• Biometrics (2)

• Journal of Clinical Oncology (2)

• Biostatistics

• Statistics in Biopharmaceutical Research

• Pharmaceutical Statistics

• Wspolczesna Onkologia (Contemporary Oncology)

Ziv Shkedy

• Biometrics

• Journal of Computational Statistics

• Controlled Clinical Trials

Marc Aerts

• Biometrics

• Statistical Modelling

• Quantiative Finance

Christel Faes

• Clinical Trials


• Biometrics (2)

José Cortiñas

• IEEE Transactions on Reliability

Roel Braekers

• Journal of the Royal Statistical Society, Ser. B

• JASA

• Canadian Journal of Statistics


Ariel Alonso

• Clinical trials

• Biometrics

Saskia Litière

• Journal of Agricultural, Biological and Environmental Statistics

Caroline Beunckens

• Statistics in Medicine

Herbert Thijs

• American Journal of Epidemiology

• Biometrical Journal


22.

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43 Referee-opdrachten van projecten, ingediend bij internationale onderzoeks-

programma's

Noël Veraverbeke

• Lid Commissie ZAP benoeming K.U.Leuven (maart 2006)

• Lid promotiecommissie Kwazulu Natal, Zuid Afrika (juli 2006)

• Beoordeling onderzoek voor NFR, Zuid Afrika (National Research Foundation)

• Project evaluator voor DFG, Duitsland (Deutsche Forschungsgemeinschaft)

(november 2006)

Geert Molenberghs

• Faculty member promotion (US : 2)

• Faculty member promotion (Canada: 1)

• Faculty member promotion (Belgium: 1)

• Project proposal for “National Science and Engineering Research Council”, Canada

• Research project evaluation (Institut National de Cancer, France)

Herbert Thijs

• Independent data monitoring committee for Sanofi Aventis

44 Lidmaatschappen van scientific committee van internationale congressen

Geert Molenberghs

• Conference of Statistical Methods in Epidemiology and Observational Studies, in

honor of Normam D. Breslow. Seattle, Washington, USA. (4 augustus 2006)

Noël Veraverbeke

• ICOTS 7, seventh International Conference on Teaching Statistics. Salvador,

Brazilië. 1-7 juli 2006. Organizatie van een sessie: “Teaching Nonparametric

Statistics”

Ziv Shkedy

• Non-clinical Statistics Conference. Potsdam, Germany. 26-28 september 2006.

Organizatie van een sessie: “Statistical methods for the exploration of surrogate

and biomarkers in functional genomics”

45 Referee-opdrachten t.a.v. internationale congressen

46 Lidmaatschappen van wetenschappelijke commissies in binnen- en buitenland

Noël Veraverbeke

• President van de Belgische Vereniging voor Statistiek (2002-2005)

• Lid van de Hoge Raad voor Statistiek (benoemd op 8 november 1998)

• Lid van het Wetenschappelijk Comité van de enquête 2001 (2001- )

• Lid van de Scientific Council van Eurandom, Eindhoven, Nederland (2004-2010)

• Lid van de stuurgroep van de FWO Wetenschappelijke Onderzoeksgemeenschap

Wiskunde (1996- )

• Lid van de jury van de Vlaamse Wiskunde Olympiade (1985- )


23.

=

• Vertegenwoordiger van FWO-Vlaanderen in de vergaderingen van Mathematics

Representatives of the European Union (Paris 2003, Stockholm 2004, Berlin 2005,

London 2006)

• Jurylid Prijs Ontwikkelingssamenwerking (2005- )

• Verantwoordelijke voor het Outreach Programme van de Bernoulli Society (2005- )

• Expert voor het Federaal Kenniscentrum voor de Gezondsheidszorg

Geert Molenberghs

• Lid van de Wetenschappelijke Commissie Wiskunde van het FWO (2003-2008)

• Lid van de Commissie voor International Wetenschappelijke Contacten van het FWO

(2003-2008)

• Vice-President, Executive Committee Member of the International Biometric Society

(2006)

• Chair of the International Representative of the American Statistical Association

Nominating Committee (2006)

Marc Aerts

• Schatbewaarder Belgische Vereniging voor Statistiek (2005- )

• Expert voor het Federaal Kenniscentrum voor de Gezondheidszorg

• Expert for the “Committee of Experts” (College van Deskundigen) for Contract

Research FPS Health, Food Chain Safety and Environment (Federale Overheidsdienst

Volksgezonheid, Veiligheid van de Voedselketen en Leefmilieu)

• Expert for the “Evaluaton Committee” (Beoordelingscommissie) for Contract

Research FPS Health, Food Chain Safety and Environment (Federale Overheidsdienst

Volksgezondheid, Veiligheid van de Voedselketen en Leefmilieu)

Paul Janssen

• Vice president Belgische Vereniging voor Statistiek

• Lid van de VLIR-werkgroep Onderzoek en IOF werkgroep

• Lid van de Vlaamse Raad voor Wetenschapsbeleid

• Voorzitter Onderzoeksraad UHasselt

• Voorzitter IOF-raad UHasselt

• FWO werkgroep onderzoeksbeleid

• Statistisch adviseur voor het Noord-Zuid-Zuid project Pilotstat (UGent) (Vietnam en

Ecuador)

5 Verwerving van extern gefinancierde onderzoeksprojecten

51 Verwerving van onderzoeksprojecten als projectleider met internationale

participatie

Geert Molenberghs

VLIR Eigen Intiatief Cuba: Biostatistics and bio-informatica Education and Research

(2006-2010)

52 Verwerving van onderzoeksprojecten als deelnemer met internationale

participatie

Marc Aerts, Ziv Shkedy


24.

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SBO-IWT (Strategisch Basisonderzoek) grant “Simulation models of infectious disease

transmission and control processes (SIMID), with applications to five major health policy

issues in Flanders,” January 1, 2007 – December 31, 2010, ism Centre for the Evaluation

of Vaccinations (Universiteit Antwerpen), Laboratory of Clinical and Epidemiological

Virology (Katholieke Universiteit Leuven), Department of Microbiology, Division of

Virology (Wetenschappelijk Instituut Volksgezondheid).

53 Verwerving van binnenlandse (nationaal of regionaal) onderzoeksprojecten

Roel Braekers, Noël Veraverbeke

Project, BOF06N03, UHasselt

The Koziol-Green and mixture Koziol-Green models with covariates under dependent

censoring.

Herman Callaert

Project “Statistiek in de media … en in de klas”. Ministerie van de Vlaamse Gemeenschap,

Project WI/2003/026 (2004-2006)

Geert Molenberghs

Consultant voor Janssen Pharmaceutica (1997-)

Consultant voor UCB (1999-)

Consultant voor Lilly (2000-)

Censtat dienstverlening: In 2006 werd gewerkt aan projecten voor ACHG Likar, Almirall

Prodesfarma nv, Altana Pharma nv, Belgian Association for Cardio-Thoracic Surgery

(BACTS), Cardinal Systems, Centrum voor Huisartsgeneeskunde-K.U.Leuven, Centrum

voor Huisartsgeneeskunde-UA, Eli Lilly, Federaal Kenniscentrum voor de

Gezondheidszorg, Federale Diensten voor Wetenschappelijke, Technische en Culturele

Aangelegenheden (DWTC), Federale Politie, Icagen Inc, Innogenetics, Integraal

Kankercentrum Zuid (IKZ), International Drug Development Institute (IDDI), Janssen

Pharmaceutica NV, Johnson & Johnson Pharmaceutical Research and Development , L.L.C,

LOOA (Limburgs Overleg Onderwijs Arbeid), Masterfoods, Mithra Pharmaceuticals s.a.,

NIS, Orafti, Polyvision, Pronota, Provincie Limburg, Rekenhof, RIZIV, Sanofi-Aventis,

Recherche & Developpement, Schering Plough nv, Studiecentrum voor Kernenergie

(SCK), Tibotec bvba, UCB, Universiteit Maastricht, UZ Antwerpen, UZ Gasthuisberg, Virga

Jesse Ziekenhuis, Vlaams Agentschap Zorg en Gezondheid, Vlaams Instituut voor

Technologisch Onderzoek (VITO), Vlaamse Interuniversitaire Raad (VLIR), Vlaamse

Regering – administratie Milieu-, Natuur-, Land- en Waterbeheer, Wetenschappelijk

Instituut Volksgezondheid (WIV), Ziekenhuis Oost-Limburg (ZOL)

Paul Janssen

Sensibiliseringsinitiatief 2007 (VLIR-UOS) (in samenwerking met de Dienst

Internationalisering en Ontwikkelingssamenwerking – S. Verlackt)

Co-promotor (samen met co-promotoren van de andere Vlaamse universiteiten) van

Steunpunt O&O Indicatoren (in samenwerking met de Dienst Onderzoek en Innovatie van

de UHasselt – A. Peters en M. Smeyers)

6 Prijzen, vermeldingen, gerealiseerde toepassingen

61 Behaalde wetenschappelijke prijzen


25.

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Geert Molenberghs

• Excellence in continuing Education Award of the American Statistical Association for

Course on Analysis of Clinical Trials: Theory and Application, presented by

Dmitrienko, A., Chuang-Stein, C., and Molenberghs, G. at the Joint Statistical

Meetings; Minneapolis, Minnesota, U.S.A. (09/08/2005). Awarded in Seattle,

Washington, U.S.A., 07/08/2006.

• Binnenlandse Francqui Leerstoel (Gembloux) (2006-2007)

Niel Hens

• Quetelet Prize 2005-2006 for a most outstanding MSc in Biostatistics project

Cristina Sotto

• Quetelet Prize 2005-2006 for a most outstanding MSc in Biostatistics project

62 Gerealiseerde toepassingen

63 Verworven oktrooien of patenten

7 Samenwerking met andere wetenschappelijke instellingen en onderzoekers

72 Verblijf van buitenlandse onderzoekers aan de UHasselt

Juan Carlos Pardo Fernàndez, University of Vigo, Spain

17 februari 2006; censored data; onderzoek

Financiering: individueel akkoord

Jelle Goeman, Universiteit Leiden, Nederland

24 februari 2006; microarray data; onderzoek


Alexandra Daskovska, UCL, Louvain-la-Neuve

3 maart 2006; econometrics; onderzoek


Elisa Molanes López, University of la Coruña, Spain

12 maart – 11 juni 2006; relative density; onderzoek

Financiering: eigen financiering

Xavier Paoletti, National Institute of Cancer, Paris, France

21 april 2006; microarrays; onderzoek


Stefan Michiels, Institut Gustave Roussy, Villejuif, France

21 april 2006; microarrays; onderzoek


Jan Swanepoel, North West University, Potchefstroom, South Afrika

22-30 april 2006; distribution function estimation; onderzoek


26.

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Financiering: BOF project

Konstantines Fokianos, University of Cyprus, Cyprus

24-30 april 2006; density ratio model; onderzoek


Lisette Sanchez, Institute op Tropical Medicine ‘Pedro Kouri’ (IPK), La Habana, Cuba

5 mei 2006; epidemiologie; onderzoek

Financiering: individueel akkoord.

Yoav Benjamini, Tel Aviv University, Israel

10-13 mei 2006; false discovery rate; onderzoek


Clarice G.B. Demetrio, Sao Paulo State University, Brazil

11-13 mei 2006; overdispersion; onderzoek en onderwijs

Financiering: UHasselt

Yi Li, Harvard University, Boston, USA

1-31 mei 2006; survival analysis; onderwijs en onderzoek

Financiering: Janssen Pharmaceutica Chair

Christoph Lange, Harvard University, Boston, USA

1-31 mei 2006; genetic data analysis; onderwijs en onderzoek

Financiering: UHasselt

Jacobo de Uña-Alvarez, University of Vigo, Spain

18-20 mei 2006; survival analysis, onderzoek

Financiering: IUAP Project

Arnold Janssen, University of Düsseldorf, Germany

18-20 mei 2006; dependence models; onderzoek


Michael Akritas, Penn State University, USA

18-25 mei 2006; survival analysis; onderzoek


Rosemary Nguti, University of Nairobi, Kenya

1-31 mei 2006; biometry; onderwijs en onderzoek

Financiering: VLIR

Paddy Farrington, Open University, Milton Keynes, U.K.

16 juni 2006; infectious diseases; onderzoek

Financiering: FWO Project

Jan Swanepoel, North West University, Potchefstroom, South Africa

5-10 september 2006; distribution function estimation; onderzoek

Financiering: BOF Project


27.

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Cornelia Swanepoel, North West University, Potchefstroom, South Afrika

5-10 september 2006; bootstrap; onderzoek


Malgorzata Cwiklinska-Jurkowska, Nicolaus Copernicus University, Bydgoszcz, Poland

1-30 september 2006; bioinformatica; onderzoek


Elisa Molanes López, University of la Coruña, Spain

27 oktober 2006; empirical likelihood; onderzoek


73 Gemeenschappelijk verricht onderzoek

Jan Swanepoel (North-West University, Potchefstroom, Zuid Afrika)

Paul Janssen en Noël Veraverbeke

Resampling, modified bootstrap and goodness-of-fit

Bilateral Scientific and Technological Cooperation

18-28 januari 2006. P. Janssen en N. Veraverbeke in Potchefstroom

22–30 april 2006. Jan Swanepoel in UHasselt

5-10 september 2006. Jan Swanepoel in UHasselt

Lichun Wang (Chinese Academy of Sciences, Beijing)

Noël Veraverbeke

Bayes and empirical Bayes estimation

Jasper Anderluch (Delft University, Nederland)

Tetyana Kadankova

Lévy processes in financial mathematics

Individueel akkoord

Ingrid Van Keilegom (UCL)

Roel Braekers

Heteroscedastic regression model with dependence between error and covariate

Individueel akkoord

Ricardo Cao and Elisa Molanes (University of La Coruña, Spain)

Paul Janssen, N. Veraverbeke

Relative density and hazard estimation

Individueel akkoord

12 maart – 11 juni 2006: Elisa Molanes in UHasselt

Luc Duchateau en Klaartje Goethals (UGent)

Paul Janssen

Frailty models, interval censoring

Individueel akkoord

Richard Sylvester (EORTC, Brussel), Cathérine Legrand (Merck Sharpe & Dohme, Brussel)

Paul Janssen

Frailty models in cancer research

Individueel akkoord

Pierre Van Damme, Philippe Beutels, Heidi Theeten, Koen Van Herck (UA), Koen Mintiens,

Stefan Roels (Centrum voor Onderzoek in Diergeneeskunde en Agrochemie), Frank

Boelaert (European Food Safety Agency), Dirk Berkvens (Instituut voor Tropische


28.

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Geneeskunde), Patrick Cras (UA), Claude Saegerman (Un Liège), Peter Teunis en Jaco

Wallinga (RIVM, Bilthoven, NL)

Marc Aerts, Ziv Shkedy, Geert Molenberghs, Christel Faes, Niel Hens, José Cortiñas,

Kaatje Bollaerts, Harriet Namata

Modelling infectious diseases

FWO en Polymod

Koen Mintiens, Ides Boone, Yves Van der Stede, Stefan Roels (Centrum voor Onderzoek

in de Diergeneeskunde en Agronomie), Stefaan Ribbens, Jeroen Dewulf (UGent), Koen

Grijspeerdt (Instituut voor Landbouw en Visserijonderzoek), Peter Teunis (RIVM,

Bilthoven, NL)

Marc Aerts, Ziv Shkedy, Christel Faes, José Cortiñas, Kaatje Bollaerts, Harriet

Namata

Microbial risk assessment and food safety

Patrick Cras, Bart Van Everbroeck, Pierre Van Damme, Philippe Beutels, Koen Van Herck

(Universiteit Antwerpen), Dirk Berkvens (Instituut voor Tropische Geneeskunde), Claude

Saegerman (Universiteit Luik), Koen Mintiens, Stefan Roels (Centrum voor Onderzoek in

de Diergeneeskunde en Agrochemie).

Marc Aerts

FWO

Koen Mintiens, Ides Boone, Yves Van der Stede (Centrum voor Onderzoek in de

Diergeneeskunde en Agrochemie), Georges Daubes, Laurent Delhalle (Universiteit Luik),

Jeroen Dewulf, Dominiek Maes (Universiteit Gent), Koen Grijspeerdt (Instituut voor

Landbouw- en Visserijonderzoek)

Marc Aerts

Project FOD Volksgezondheid

Frank Buntinx, Ann Van der Bruel (KULeuven)

Marc Aerts

Europees project POLYMOD: Pierre Van Damme, Philippe Beutels (Universiteit

Antwerpen), Peter Teunis, Jacco Wallinga (RIVM) + 14 European partner research

institutes

Marc Aerts

Europees project Polymod

Heidi Theeten en Pierre Van Damme (Universiteit Antwerpen), Corinne Vandermeulen,

Mathieu Roelants, Karel Hoppenbrouwers, Anne-Marie Depoorter (VUBrussel)

Marc Aerts

Jeffrey Simonoff (New York University, USA)

Marc Aerts, Niel Hens

Model selection after presmoothing

Individueel akkoord

Mike Kenward (London School of Hygiene and Tropical Medicine, UK)

Marc Aerts, Geert Molenberghs, Herbert Thijs, Niel Hens, Ivy Janssen, An Creemers

Incomplete clinical trial data

ESRC Grant

Diverse bezoeken in 2006

Kostas Fokianos (University Cyprus, Nicosia, Cyprus), Frank Buntinx (K.U.Leuven)

Niel Hens, Marc Aerts

The ROC curve

Individueel akkoord

Kristen Van Steen, Els Goetghebeur, Stijn Vansteelandt (UGent), Mike Kenward (London),

Cristina Sotto, An Creemers, Dimitris Rizopoulos, Sypridoula Tsonoka


29.

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Geert Molenberghs, Marc Aerts, Herbert Thijs, Ivy Janssen, Caroline Beunckens

Missing data and sensitivity analysis

Individueel akkoord

Didier Renard (Eli Lilly), Tony Vangeneugden, Fabian Tibaldi

Geert Molenberghs, Tomasz Burzykowski, Helena Geys, José Cortiñas, Ariel Alonso,

Ziv Shkedy, Abel Tilahun, Pryseley Assam

Surrogate markers

Individueel akkoord

Paul Eilers (Leiden Universiteit, NL)

Kaatje Bollaerts, Marc Aerts

Splines

Individueel akkoord

John Edmunds and Nigel Gay (Health Protection Agency, London, UK)

Niel Hens

Infectious diseases; modelling contact patterns

1-18 mei 2006; Niel Hens in London

13-16 december 2006: Niel Hens in London

Polymod project

Leen Decin, Conny Aerts (K.U.Leuven)

Ziv Shkedy

Astrostatistics

Individueel akkoord

Henry Mwambi (University of Kwazulu Natal, South Africa)

Ziv Shkedy

Infectious diseases

Individueel akkoord

Geert Verbeke (K.U.Leuven), Mike Kenward (London)

Christel Faes

Effective sample size and degrees of freedom

Individueel akkoord

Paul De Boeck, Dirk Smits, Geert Verbeke, Edward Ip, Yuri Goeghebeur (K.U.Leuven)

Geert Molenberghs

Logistic mixed models in items response theory

Individueel akkoord

Geert Verbeke (K.U.Leuven)

Geert Molenberghs

Models for discrete repeated measures

Individueel akkoord

Geert Verbeke, Iven Van Mechelen, Francis Tuerlinckx (K.U.Leuven)

Geert Molenberghs

Methods for optimization in statistics

Individueel akkoord

Michael Kenward (London), Raymond Caroll (Texas A&M University), Craig Malinckrodt

(Eli Lilly, Indianapolis, USA)

Geert Molenberghs, Caroline Beunckens, Ivy Jansen, Cristina Sotto

Missing data in clinical trials

Individueel akkoord

Carmen Cadarso Suarez (Santiago de Compostela, Spain)

Geert Molenberghs, Helena Geys, Ariel Alonso, Christel Faes

Statistical analysis in neuro firing rates


30.

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Individueel akkoord

Kennedy Otwombe (University of Witwatersrand, Johannesburg, South Africa)

Niel Hens

EM-algorithm by the method of weights

Individueel akkoord

Natalia Kwasnikowska, Kerstin Koch, Jan Van den Bussche, Frank Neven (Infolab,

UHasselt)

Tomasz Burzykowski, Ivy Jansen

Gene-pathway findings

Individueel akkoord

Didier Renard (Eli Lilly, Belgium), Christelle Darstein (Eli Lilly, USA)

Ariel Alonso, Saskia Litière, Annouschka Laenen, Geert Molenberghs

Surrogate markers

Individueel akkoord

Luc Bijnens (Janssen Pharma), Luc Wouters (Barrier Therapeutics)

Dan Lin

Microarray data

Individueel akkoord

Ann Cuypers, Karen Smeets, Joske Ruytinx (Environmental Biology, UHasselt)

Ivy Jansen

Microarray data

Individueel akkoord

George Daube (UL), Lieven De Zutter (UG), Koen Grijpeerdt (CLO), Koen Mintiens

(CODA), Herman Van Oyen (WIV)

Kaatje Bollaerts, Marc Aerts, Ziv Shkedy

Individueel akkoord

NIS (Nationaal Instituut voor de Statistiek) en vijf Belgische Onderzoeksgroepen (VUB,

UCL, UA(2), UHasselt)

Veerle Vandersmissen, Liesbeth Bruckers, Geert Molenberghs

Vervanging van de Census door administratieve databanken en enquêtes

WIV (Wetenschappelijk Instituut Volksgezondheid)

Veerle Vandersmissen

Gezondheidsenquête

Individueel akkoord

Kristof Engelen

Dirk Valkenborg

Microarray data

Individueel akkoord

Jean-Paul Noben

Dirk Valkenborg

Protemics

Individueel akkoord

Dani Yekutieli, H.W.H. Göhlmann, An De Bondt, Tim Perera, Tamara Geerts, Ilse Van den

Wijngaert, Luc Bijnens

Dan Lin, Tomasz Burzykowski, Ziv Shkedy

Microarray experiments

Individueel akkoord

Roel Straetemans (Janssen Pharma)

Tom Jacobs, Geert Molenberghs


31.

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Mixed effects modeling

Individueel akkoord

University of Havana, Cuba

Geert Molenberghs, José Cortiñas

Training and Research program in medical statistics and bioinformatics (preparation

of a VLIR-Own Initiative Project)

26 november – 12 december: José Cortiñas in Cuba

Diverse bezoeken van Geert Molenberghs aan Cuba

Centro de Immunologia Molecular (CIM) and Instituto de Medicina Tropical “Petro Kouri”

(IPK), Havana, Cuba

Saskia Litière, Ziv Shkedy

Individueel akkoord

11 oktober – 23 november 2006: Saskia Litière in Cuba

Luc Bijnens (Janssen Pharma)

Christel Faes

Use of penalized splines

Individueel akkoord

==

74 Onderzoek, specifiek in samenwerking met de Universiteit Maastricht

Activiteitenverslag - Voordrachten op nationale of regionale congressen, studiedagen, symposia,

workshops Herman Callaert

• 18 november 2006. Eekhoutcentrum West Vlaanderen, Kortrijk. Op exploratie in de statistiek: nieuw en boeiend

• 1 en 8 februari 2006 (Kenniscentrum Aalst), 15 en 22 februari 2006 (UHasselt), 8 en 15 maart 2006 (K.U.Leuven). Exploratieve statistiek voor het secundair onderwijs. Nascholingen voor leerkrachten wiskunde van het secundair onderwijs

Geert Molenberghs

• 22-23 februari 2006, K.U.Leuven. Interuniversity Graduate School of

Psychometrics and Sociometrics, IUAP/PAI Network

Mixed models and incomplete data

• 27 april 2006, SAS Academic Day, Brussel.

Analysis of incomplete longitudinal data

• 28-29 april 2006. Hotel La Réserve, Knokke.

Permanente Vorming 2005-2006, K.U.Leuven

Ontwikkeling van tools voor gegevensverzameling binnen de geestelijke

gezondheidszorg. Cursus: Geestelijke Gezondheidszorg 2015.

• 2-3 mei 2006, K.U.Leuven

Interuniversity Graduate School of Psychometrics and Scientometrics, IUAP/PAI

Network

Numerical techniques for statisticians


32.

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• 18 mei 2006, Brussel

Interuniversitair doctoraat medische wetenschappen Incomplete Data

• 12 juni 2006, K.U.Leuven Leuven Statistical Day Opportunities and challenges in mixed models and incomplete data

• 23 juni 2006, Universiteit Hasselt Formal and informal model selection and assessment when data are incomplete

• 27 november 2006, K.U.Leuven International seminar: Non-response and coverage problems in telephone surveys Incomplete data in surveys: the Slovenian Public Opinion Survey

Roel Braekers

• 5 mei 2006, U.C.L., Louvain-la-Neuve

A conditional Koziol-Green model under dependent censoring.

Marc Aerts

• 22 september 2006. 14th Annual Meeting of the Flemish Society for veterinary

epidemiology and economics, Gent.

Predictive value of sperm motility characteristics and morphology on reproductive

performance in sows.

Ziv Shkedy

• 11 – 13 oktober 2006. 14th Annual Meeting of the Belgian Statistical Society,

Houffalize.

Estimating the force of infection from serological data: past, present and future;

An overview of 78 years of statistical solution for epidemiological problem (invited

talk)

Tomasz Burzykowski

• 22 september 2006, Tervuren. Bioscope-IT

Workshop in Biostatistics

Dealing with missing data

Niel Hens

• 19 mei 2006, K.U.Leuven. IUAP: Recent developments in the analysis of repeated

measurement studies in the presence of missing data;

Some issues in modelling incomplete longitudinal data using selection models

Saskia Litière

• 24 maart 2006, Universiteit Hasselt. The impact of misspecifying the random-

effects distribution on maximum likelihood estimation in generalized lineair mixed

models

• 12 mei 2006. Universiteit Hasselt. The impact of misspecifying the random-effects

distribution on maximum likelihood estimation in generalized lineair mixed models

Tetyana Kadankova


33.

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• 10 februari 2006. Koninklijke Vlaamse Academie van België, Brussel. 4th Actuarial

and Financial Mathematics Day

Several two-boundary problems for Lévy processes.

Harriet Namata

• 16-17 maart 2006. UCL, Louvain-la-Neuve.

Estimation of microbial risk using AIC model averaging approach.

• 12 mei 2006. Universiteit Hasselt

Estimation of microbial risk using AIC model averaging approach.

An Creemers

• 12-13 oktober 2006. 14th Annual Meeting of the Belgian Statistical Society,

Houffalize.

A new nonparametric approach to weighted estimating equations for missing data.

Dirk Valkenborg


Houffalize.

Monoisotopic peak validation using a Poisson approximation in a combined

fractional diagonal chromatography and mass spectometry setting.

• 7-8 december 2006. Conference on Proteome Analysis in Systems Biology,

Antwerpen.


fractional diagonal chromatography and mass spectometry setting.

• 23 november 2006. Associatie Universiteit Hogescholen Limburg: Dag van het

onderzoek, Diepenbeek.

An algorithm to process and analyse COFRADIC data (poster)

• 23 november 2006. Associatie Universiteit Hogescholen Limburg: Dag van het

onderzoek, Diepenbeek.


fractional diagonal chromatography and mass spectometry setting. (poster)

• 7-8 december 2006. Conference on Proteome Analysis in Systems Biology,

Antwerpen.

An algorithm to process and analyse COFRADIC data (poster).

Liesbeth Bruckers

• 21- 22 september 2006. Derde Vlaams Geestelijk Gezondheidscongres, Brussel.

Persisterend Storend Gedrag.

Abel Tilahun


Houffalize.

Longitudinal analysis of drug induced changes in EEG data in rats.

Lien Beunckens

• 28 april 2006. SAS Academic Day, Brussel.

Analysis of incomplete longitudinal data.


34.

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• 19 mei 2006. K.U.Leuven, IUAP: Recent developments in the analysis of repeated

measurements studies in the presence of missing data.

A latent class mixture model for dealing with incomplete longitudinal data.

Veerle Vandersmissen

• 31 januari 2006. Wetenschappelijk Instituut Volksgezondheid, Brussel.

De gezondheidsenquête: multiple imputatie.

Tom Jacobs


Houffalize.

In vivo – in vitro correlation data modelling and random efects: a case study.

Philippe Haldermans


Houffalize;

Using linear mixed models for normalization of cDNA microarrays.

An Creemers


Houffalize.

A new nonparametric approach to weighted estimated equations for missing data.

Kaatje Bollaerts

• 22 september – 1 november 2006. VEE-study day, Merelbeke.

Identification of salmonella risk factors in pig farms.

John Maringwa

• 16 maart 2006. Belgische Vereniging voor Nefrologie, Gent

The defence status of murine kidneys exposed to low concentrations of Cadmium:

from metal scavenging proteins to antioxidant detoxification (poster) (awarded)

Binnenlandse bezoekers (seminarie)

• Katrien Declercq, S.A.S., 13 januari 2006

• Philippe Beutels, Universiteit Antwerpen, 14 april 2006

• Pierre Van Damme, Universiteit Antwerpen, 28 april 2006

• Thierry Van Effelterre, Glaxo-Smith-Kline, 9 juni 266

Congressen (passieve deelname)

Noël Veraverbeke

• Fourth Actuarial and Financial Mathematics Day, Brussel, 10 februari 2006.

• Bijeenkomst Stochastici. Lunteren, Nederland, 13-15 november 2006.

• Franqui Chair Inaugural Lecture, Leuven, 22 november 2006.

• Lezingennamiddag, Eurandom, Eindhoven, Nederland, 23 november 2006.

• One Day Meeting IAP Network. K.U.Leuven, 19 mei 2006.


35.

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Herman Callaert

• National Council of Teachers of Mathematics Conferences. St. Louis, 26-29 april 2006.

Phoenix, 4-7 oktober 2006.

Roel Braekers

• Workshop 5. Flexible Statistical Analysis adepted to complex data structures, Louvain-

la-Neuve, 16-17 maart, 2006.

• One Day Meeting on Survival Analysis, Diepenbeek, 19 mei 2006.

Ivy Jansen

• European Mathematical Genetics Meeting, Cardiff, Wales, 6-7 april 2006.

• Belgian Statistical Society, Houffalize, 12-13 oktober 2006.

• Symposium on Proteone Analysis in Systems Biology, Antwerpen, 7-8 december 2006.

Niel Hens

• Symposium Mathematical Models of Infectious Diseases as advanced tools in

epidemiology and public health, Bilthoven, Nederland, 27 januari 2006.

• Belgian Statistical Society, Houffalize, 12-13 oktober 2006.

José Cortiñas

• One Day symposium Discovering the false discovery rate: multiple inference in

genomics, Hasselt, 11 mei 2006.

Dirk Valkenborg

• 6th Micro Array Usergroup Meeting, Leuven, 13-15 november 2006.

Saskia Litière

• IT – 2006 Targeting Complexity, Center of Molecular Immunology, Havana, Cuba, 15-

19 november 2006.

Cristina Sotto

• One Day Meeting IAP Network, K.U.Leuven, 19 mei 2006.

Harriet Namata

• Symposium on mathematical models for infectious diseases control, RIVM Bilthoven,

Nederland, 27 januari 2006.

• One Day Symposium on survival analysis. IAP Research Network in Statistics, Hasselt,

19 mei 2006.

• Workshop Tools for infectious disease modeling, Cairns, Australia, 13-15 augustus

2006.


36.

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Christel Faes

• International workshop on spatio-temporal modelling, Pamplona, Spain, 27-29

september 2006.


- Uitnodigingen van UHasselt-stafleden als gasthoogleraar aan buitenlandse universiteiten of op zomerscholen

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