Onderzoeksgroep: STATISTIEK 2009 A Identiteit van de ...- Reliability estimation in clinical trial...

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Onderzoeksgroep: STATISTIEK 2009

A Identiteit van de deelnemende onderzoekers

Aerts Marc, Alonso Ariel, Bijnens Luc, Birhanu Teshome Ayele, Braekers Roel, Bruckers

Liesbeth, Burzykowski Tomasz, Buyse Marc, Castro Sanchez Yovanna Amparo, Cortiñas

Abrahantas José, Creemers An, Del Fava Emanuele, Duchateau Luc, Faes Christel, Gaddah

Auguste, Geys Helena, Girma Minalu, Gitome Arthur, Goeyvaerts Nele, Lin Dan, Haldermans

Philippe, Hens Niel, Janssen Paul, Kasim Adetayo, Laenen Annouschka, Lesaffre Emmanuel,

Litière Saskia, Molenberghs Geert, Pramana Setia, Qi Zhu, Renard Didier, Rizopoulos Dimitris,

Serroyen Jan, Skhedy Ziv, Sotto Cristina, Thijs Herbert, Van Effelterre Thierry, Van Rompaye

Bart, Van Sanden Suzy, Veraverbeke Noël, Verbeke Geert, Weyler Joost, Winters Bart,

Wouters Luc.

Uit dienst gegaan in 2009:

Beunckens Caroline (15.04.09), Bollaerts Kaatje (30.06.09), Callaert Herman (30.09.09),

Jacobs Tom (31.05.09), Jansen Ivy (31.05.09), Kadankova Tetyana (31.10.09), Massonnet

Goele (01.09.09), Pryseley Assam Nkouibert (30.09.09), Tilahun Eshete Abel (30.06.09),

Valkenborg Dirk (12.09.09), Van Keilegom Ingrid (30.09.09).

In dienst gekomen in 2009:

Claesen Jurgen (01.10.09), Geerdens Candida (15.09.09), Grouwels Yves (01.10.09), Habteab

Ghebretinsae Aklilu (01.10.09), Khamiakova Tatsiana (01.09.09), Milanzi Elasna (01.10.09),

Neyens Thomas (01.10.09), Njeru Edmund (01.10.09), Nysen Ruth (15.09.09), Prenen Leen

(01.09.09).

B Titel(s) van het (de) onderzoeksproject(en)

a. Mathematische statistiek

b. Biostatistiek

c. Bioinformatica

C Beschrijving van de ontwikkelde onderzoeksactiviteit(en) per project

- Use of Bernstein polynomials to estimate copulas (NV, PJ, Jan Swanepoel)

- Extension of Koziol-Green model (NV, Jacobo de Uña Alvarez)

- Copula process with covariates (NV)

- Empirical likelihood for non smooth criterion function (NV, Ingrid Van Keilegom, Elisa

Molanes)

- Weak convergence for copula estimator (NV, Irène Gijbels, Marek Omelka)

- Risk theory (NV, Stéphane Loisel, Claudio Macci, Romain Biard)

- Difference of compound Poisson and compound renewal process (TK)

- Two-boundary characteristics (TK)

- Queueing systems with limited waiting room and applications (TK)

- Extension of the Koziol-Green model by introducing a copula on the censoring time and the

lifetime (RB, AG)

= O=

- Further extension to dependent censoring and a semi-parametric copula family (RB, AG)

- Extension to the covariate case (RB, AG)

- Semi-parametric zero-inflated Cox regression model for left-censored data (RB, Paul Markel)

- Zero-inflated Cox regression model for left-censored multivariate data (RB, YG)

- Local measures of association between different lifetimes (RB, LP)

- Goodness-of-fit test for four-dimensional copula models (GMa, PJ, Luc Duchateau)

- Frailty models with time varying coefficients and time varying frailty under right censoring

(Catherine Legrand, Luc Duchateau en PJ)

- Fitting frailty models via transformations: the continuous case (Ricardo Cao, Ignacio Lopez

de Ullibarri, PJ)

- Flexible modeling of frailty densities (Gerda Claeskens, CG, PJ)

- Multivariate max-id distributions and correlated frailties (Luc Duchateau, CG, PJ)

- Goodness-of-fit for frailty models (Goele Massonnet, CG, PJ)

- Extending Beran estimator for interval-censored data (Ricardo Cao, NV, PJ)

- Missing data and sensitivity analysis (GM, MA, HT, IJ, CB, CS, AC, Geert Verbeke, Dimitris

Rizopoulos, Sypridoula Tsonaka, Michael G Kenward, EN, BT, George Kalema)

- Missing data in clinical trials (GM, Michael G. Kenward, Raymond J. Caroll, Craig Mallinckrodt,

CB, IJ, CS)

- Pattern-mixture models (GM, HT, Michael G. Kenward, CB, IJ)

- Surrogate markers (GM, TB, Helena Geys, Fabian Tibaldi, JC, AA, ZS, Tony Vangeneugden,

Didier Renard, AT, PA, EM)

- Logistic mixed models in item response theory (GM, Geert Verbeke, Paul De Boeck, Dirk

Smits, Edward Ip, Yuri Goegebeur)

- Models for discrete repeated measures (GM, Geert Verbeke)

- Small-sample degrees of freedom (GM, CF, MA, Geert Verbeke, Michael G. Kenward)

- Methods for clustered data (MA, HC, CF, GM, AH)

- Models for infectious diseases (MA, ZS, GM, NH)

- Methods for optimization in statistics (GM, Geert Verbeke, Francis Tuerlinckx)

- Psychometric methods in clinical studies (GM, AL, AA, Tony Vangeneugden, Clarice

Demétrio)

- Combined longitudinal-overdispersed models (GM, Geert Verbeke, Clarice Demétrio, Tony

Vangeneugden, Afranio Vieira, George Kalema, BT, AH, EM, EN, Samuel Iddi, Achmed Efendi,

Mehreteab Fantahun, RB, ZS, MA,CF, TN, NH)

- Pseudo-likelihood for incomplete data (GM, Geert Verbeke, BT, Michael G. Kenward, Achmad

Efendi)

- Methods of the analysis of microarray data (TB, SV, DL, ZS)

- Methods of the analysis of mass-spectrometry data (TB, DV, QZ, TB, IJ, AK)

- Validation of surrogate endpoints in multiple randomized clinical trials (TB, Marc Buyse)

- Clinical trial designs (TB, Marc Buyse)

- Infectious disease modeling (CF)

- Spatio-temporal spread of infectious diseases (CF)

- Spatial distribution of Bluetongue in Belgium, Germany and the Netherlands (CF)

- Variational approximation methodology in the context of Bayesian analysis of incomplete

data (CF)

- Effective sample size calculation of correlated data (CF)

- Veterinary epidemiology and surveillance of emerging diseases (CF)

- Infectious diseases and microarray analysis (ZS)

- Modeling infectious diseases (MA, NH, CF, YC, NG)

- Microbial risk assessment, zoonotic, diseases, vectorborne diseases and food safety (MA, …)

- Topics in correlated frailty models (MA, NH, GM, Andreas Wienke)

P=

- Topics in latent class analysis and diagnostic tests (MA, JC, CF, NH, GMi)

- Topics in missing data and sensitivity analysis (MA, GM, HT, NH, AC, EN, Geert Verbeke,

Mike Kenward)

- Topics in statistical models for environmental data with nondetects (MA, CF, RN, Pietro

Ferrari)

- Topics in meta-analysis of coronary heart disease in primary care: the accuracy of the

history of physical findings, a systematic review with individual patient data (MA, …)

- Inferring epidemic trees from partially observed data (NH, Jacco Wallinga (University of

Utrecht, The Netherlands)

- Modelling distortions in seroprevalence data using change-point fractional polynomials (NH,

Andrea Kvitkovicova, David Hlubinka (Charles University, Prague) and MA)

- Elucidation on differences in the sero-epidemiology of VZV and B19 in five European

countries (NH, John Edmunds, Nigel Gay and Alessia Melagaro (Health Protection Agency,

London, UK)

- Bayesian adaptive splines for non-normal data (NH, JM, CF, Helena Geys, CH, and Carmen

Cardarso Suárez)

- A new nonparametric approach to weighed estimating equations for missing data (NH, AC,

MA, GM)

- Flexible generalized estimating equations as a new technique to perform a cost-effectiveness

analysis for pneumococcal infections (NH, AC, MA, ZS, Beutels, P. and de Smet, F.)

- Hierarchical semiparametric Bayesian models for the force of infection for parvovirus B19

(NH, Namata H., ZS, MA, CD, Van Damme P., Beutels, P.)

- Model selection after presmoothing (NH, MA, Jeff S. Simonoff (Leonard N. Stern School of

Business, New York University)

- Eearly waning of varicella and rubella antibodies (NH, Leuridan, E., Hutse, V., Ieven, M. MA,

Van Damme, P.)

- Vaccine coverage and willingness to pay (NH, Theeten, H., MA, Vandermeulen, C., Roelants,

M., Hoppenbrouwers, K. and Van Damme, P.)

- Estimating the incidence of symptomatic rotavirus infections: a systematic review and meta-

analysis (NH, Bilcke, J., Van Damme, P., Van Ranst, M., MA, Beutels, P.)

- Modelling hepatitis A in Belgium, the influence of migration (NH, Lejeune, O., Bilcke, J.,

Beutels, P.)

- Hospital infections and factors determining the spread of pathogens (NH, Marieke Deregt and

Marc Bonten (Utrecht University, The Netherlands), YC, MA)

- Estimating the contact matrix using tensor-product B-splines (NH, Paul Eilers (Utrecht

University, The Netherlands) and Carlo Giovanni Camardo (Max Planck Institute for

Demographic Research, Rostock, Germany)

- H1N1 in the early stages in Europe (NH, Stefan Flassche, John Edmunds, … (Health

Protection Agency, UK)

- School closure and pandemic influenza (NH, Thomas House, Matt Keeling, … (University of

Warwick, Warwick, UK)

- Estimating the delay in stochastic epidemic models (NH, Slavik Koval, Odo Diekmann and

Marc Bonten (Utrecht University, The Netherlands)

- Estimating network structures from egocentric data (NH, Gail Potter, Ira Longini, Betz

Halloran, Mark Handcock (University of Washington, Seattle, US)

- Modelling bivariate current status data (NH, Andreas Wienke (Martin-Luther-University Halle-

Wittenberg)

- Supervised learning techniques, classification of psychotropic drugs and gait patterns (JC,

Kristien Wouters)

= Q=

- Alternative methods to evaluate surrogacy, using supervised learning methodology (JC, GM,

ZS)

- Solution for separation problems in logistic regression with clustered data (JC)

- Survival analysis, dealing with clustered interval censored data (JC)

- Identification of risk groups using mixture models (JC)

- Assessing antibiotic resistance using logistic models with clustered binary data with

separation issues (JC)

- Projects for the European Food Safety Agency (JC, MA, SL)

- Modelling prevalence and force of infection on case notification and serological data (KB, MA,

ZS, NH, Beutels (UA), Van Damme (UA))

- Ontwikkeling van een methodologie voor de kwantitatieve beoordeling van zonotische risico’s

toegepast op het model Salmonella bij varkens (KB, MA, ZS; UL: George Daube; Ugent:

Lieven De Zutter; ILVO: Koen Grijspeerdt; CODA: Koen Mintiens)

- Dose-response study of microarray experiments (DL, SP, AK, ZS, An de Bondt, Willem

Talloen, Hinrich Goelhmann, Luc Bijnens)

- Book project: Dose-response modeling of gene expression data using R (expected to

complete by April 2011) (DL, ZS, Dhammika Amaratunga, Dani Yekutieli and Luc Bijnens)

- Informative and non-informative calls for gene filtering in affymetrix experiments using

linear mixed models (DL, AK, SV, ZS, An de Bondt, Willem Talloen, Hinrich Goelhmann, Luc

Bijnens, Sepp Hochreiter, Djork Clevert)

- Extension of informative and non-informative calls using linear mixed model (DL, AK, TK, ZS,

Geert Verbeke, Willem Talloen, Hinrich Goelhmann, Luc Bijnens)

- Selection and evaluation of genomic biomarkers (DL, AT, ZS, An de Bondt, Willem Talloen,

Hinrich Goelhmann, Luc Bijnens)

- Two-way unsupervised classification techniques (biclustering algorithms and methods),

simulation studies and evaluation strategy for unsupervised classification methods (settings,

similarity scores) (TKh, DL, SV, AK, ZS)

- Pre-processing methods for microarray data, probe-level filtering (INI calls) with adjustment

for covariates (TKh, AK, DL, ZS)

- Incomplete data (EN)

- Surrogate markers, psychometric evaluation of rating scales, inference in generalized linear

mixed models under misspecification, diagnostic tools, survival analysis, information theory

(AA, SL, AL, AT, AP, EM, DL, ZS)

- Lack-of-fit tests for left-censored and interval-censored analytical data in food risk

assessment (RN)

- Psychometric validation and correlation functions (EM)

- Evaluation of biomarkers and surrogate endpoints in life sciences and biopharmaceutical

research (EM)

- Reliability estimation in clinical trial data with repeated measurements (AL, AA, GM, Tony

Vangeneugden)

- Reliabiity estimation based on multi-item instruments (AL, AA, Gm, Tony Vangeneugden)

- Applications of the methodology to quality of life scales in cancer clinical trials (AL, AA, GM,

Tony Vangeneugden)

- Bayesian approach to model the overlapping peptides; Bayesian and frequentist approaches

to model the enzymatically 18O-labelled mass spectra with heteroscedasticity and/or rand

effects (QZ, TB, Dirk Valkenborg)

- Testing and modeling of dose-response relationship in a pre-clinical microarray experiment

(SP, DL, ZS)

- Isogene graphical user interface (IsogeneGUI) R package (SP, PH, DL, ZS)

R=

- Multiple contrast test (MCT) for detecting monotonic trends using gene expression data (SP,

PH, DL, ZS)

- Order restricted semi-parametric inference for testing dose-response relationship in pre-

clinical microarray experiments (SP, DL, ZS)

- Biclustering techniques (SP, TK, SV, DL, AK, PH, ZS)

- Diagnostic tools to detect model misspecification in generalized linear mixed models (SL, AA,

GM)

- Biosurveillance methodology (SL, CF, MA)

- Normalization of microarrays (PH, ZS, SV, DL, AK, AG, SP)

- Connection dose-response data + microarrays (PH, ZS, SV, DL, AK, AG, SP)

- Gene signatures for irritable bowel syndrome (AK, ZS, DL, SV, JC, H. Goehlmann, L.

Bijnens, D. Yekutieli, M. Camilleri, J. Aerssens and W. Talloen)

- Informative/noninformative calls for gene expression (AK, ZS, DL, H. Goehlmann, L. Bijnens,

W. Talloen, S. Hochreiter and D-A. Clevert)

- Bayesian inequality model for dose-response microarray experiments (AK, ZS, DL, H.

Goehlmann, L. Bijnens and W. Talloen)

- Order restricted clustering for dose-response microarray experiments (AK, ZS, DL, H.

Goehlmann, L. Bijnens and W. Talloen)

- Cell line based compound priorization and response prediction (TKh, SP, AG, AK, PH, DL, SV,

ZS, H. Goehlmann, L. Bijnens, S. Dickens, A. De Bondt, W. Talloen, A. Mayr, A. Mitterecker,

S. Hochreiter, D-A. Clevert)

- Analysis of microarray data: biomarkers, analysis based in Laplace distribution, biclustering,

pilot studies for using Gene Titan (SV, DL, ZS, AT, AK, AG, SP)

- Micro RNA’s: a comparison of different platforms (SV and Janssen Pharmaceutica)

- Amsterdam Cohort study on time to HiV and hepatitis C infection in injecting drug users (YC,

MA, NH, ZS, Lucas Wiessing, M. Kretschmar)

- Construction of metabolomic biomarkers for multiple sclerosis (AG, AK, DL, SV, ZS)

- Resampling based multiple testing in microarray experiments (AG, AK, DL, SV, ZS)

- Probiotics study: extending the interval censored methodology to time dependent covariates

(YC, NK, M. de Regt)

- Phylogenetics analysis of HCV virus (YC)

- Estimating infectious disease parameters from data on social contacts and serological status

(NG, NH, B. Ogunjimi, MA, ZS, P. van Damme, P. Beutels)

- Estimating the impact of school closure on social mixing behaviour and the transmission of

close contact infections in eight European countries (NG, NH, GMi, MA, J. Mossong, W.J.

Edmunds, P. Beutels)

- Statistical inference on parovirus B19 immunology using data on social contacts and

serological status (NG, NH, W.J. Edmunds, MA, P. Beutels)

- Modern cluster methods for incomplete longitudinal data. Growth mixture modeling (LB, GM)

- Topics in analysis and sensitivity analysis for incomplete longitudinal data (CS, GM)

- MCMC-based estimation methods for continuous longitudinal data with non-random (non-)

monotone missingness (CS, CB, GM, M. Kenward)

- A comparison of various software tools for dealing with missing data via imputation (CS, JC,

GM)

- Extensions of latent class mixed models stochastic EM for Gaussian longitudinal data with

missingness (CS, GM, CB)

- The study of mixtures of max-id distributions as an alternative for the correlated frailty

model (L. Duchateau, CG, PJ)

- Flexible modeling of the family distribution (G. Claeskens, CG, PJ)

- Goodness-of-fit (based on empiral copulas) (GC, PJ, GMa)

= S=

- Constructing new methods to analyze spatial data, as a part of larger project to build a

powerful modeling framework for the design and analysis of life sciences studies (TN, CF,

GM)

- Statistical analysis of the co-infection between HCV and HIV in injecting drug users (IDUs)

(ED)

- Estimation of the prevalence and the force of infection of airborne infectious diseases by

means of mixture models (ED)

- Estimation of the force of infection and the prevalence of airborne infectious diseases by

means of social contact matrices and time-use data (ED, P. Manfredi (University of Pisa, IT))

- Consultancy for EFSA: analysis of the baseline survey on the prevalence of Campylobacter in

broiler caeca and broiler carcasses and on the prevalence of Salmonella in broiler carcasses,

in the EU, 2008 (ED, YC, SL, JC)

- Pseudo-likelihood estimation for incomplete data (BT)

- Quantitative mass spectrometry (MS) based proteomics. Enzymatic 18O-labeling and disrete-

time markov chain models (JCl)

- Missing data: a new method to handle missing covariates (AC, MA, NH), shared parameter

models and MAR (AC, GM, NH, MA, G. Verbeke, M. Kenward), sensitivity analysis for the

shared parameter model (AC, GM, NH, MA, G. Verbeke, M. Kenward)

- Medical costs in infectious diseases (pneumococcal disease) (AC, MA, NH, ZS, P. Beutels)

- Using statistical methodology for integrated vaccine and microbiological research, with a

focus on antibiotic use and the containment of antibiotic resistance (GMi, MA)

- Use for developmental toxicology and risk assessment (AH, CF, GM, H. Geys)

- Assessment of type I error rate in Alzheimer’s disease trial (AH)

D Mededelingen van resultaten van het onderzoekswerk

1 Doctoraats- en aggregaatsthesissen

11 In de onderzoeksgroep behaalde doctoraten

Kaatje Bollaerts

Statistical models in epidemiology and quantitative microbiol risk assessment applied to

salmonella in pork.

8 mei 2009.

Supervisor: Marc Aerts

Tom Jacobs

Non-linear mixed-effects modeling of complex biopharmaceutical data.

20 mei 2009.

Supervisor: Geert Molenberghs

Abel Tilahun

Marker methodology with focus on hierarchical outcomes.

29 mei 2009.


Cristina Sotto

Analysis in sensitivity analysis for incomplete data.

9 september 2009.


Tetyana Kadankova

Two-sided exit problems for several classes of stochastic processes.

T=

18 september 2009.

Supervisor: Noël Veraverbeke

Pryseley Assam Nkouibert

Marker methodology with focus on time-to-event outcomes.

25 september 2009.

Supervisor: Geert Molenberhgs

12 (Co)promoties van doctoraten, niet behaald aan de UHasselt

/

13 Lidmaatschappen van jury's van buitenlandse doctoraten

Noël Veraverbeke

31 maart 2009. Charles University, Prague, Czech Republic. Opponent voor habilitation

thesis van Michal Kulich. “Statistical methods for the analysis of two-phase studies”.

April 2009. North-West University, Potchefstroom, South-Africa. Jurylid voor doctoraat

van James Allison. “Bootstrap-based hypothesis testing” (promotor: Jan Swanepoel)

Geert Molenberghs

januari 2009. University of Kwazulu Natal, South Africa. Jurylid voor doctoraat van

Thembile Mzolo. “Estimating risk determinants of HIV and TB in South Africa.

3 juni 2009. Université de Paris VI, Paris, France. Rapporteur voor doctoraat van

Kaouthar El Fassi. “Sur l’estimation non-paramétrique de la fonction d’égalisation

équipercentile. Application à la qualité de vie”. (promotor: Mounier Mesbach)

14 Lidmaatschappen van jury's van binnenlandse doctoraten

Noël Veraverbeke

10 december 2009. Katholieke Universiteit, Leuven. Jurylid voor doctoraat van Lieven

Desmet. “Local estimation of irregular curves with applications”. (promotor: Irène Gijbels)

Geert Molenberghs

9 januari 2009. Universiteit Hasselt. Jurylid voor doctoraat van Tom Cornelissen. “Flash

pyrolysis”. (promotor: Jan Yperman)

Marc Aerts

27 april 2009. K.U.Leuven. Jurylid voor doctoraat van Fabrizio Consentino. “Model

selection with incomplete data”. (promotor: Gerda Claeskens)

= U=

2 Wetenschappelijke publicaties

Internationale wetenschappelijke publicaties

20 Gepubliceerde artikels in internationale tijdschriften (opgenomen in de JCR1 of

in een door de Onderzoeksraad erkende alternatieve tijdschriftenlijst)

Kadankov, V., Kadankova, T. and Veraverbeke, N. (2009). Intersections of an interval by a

difference of a compound Poisson process and a compound renewal process. Stochastic

Models, 25, 270-300.

Wang, L. and Veraverbeke, N. (2009). Bayes prediction based on right censored data.

Statistical Papers, 50, 137-149.

Molanes, E.M., Van Keilegom, I. and Veraverbeke, N. (2009). Empirical likelihood for non-

smooth criterion functions. Scandinavian Journal of Statistics, 36, 413-432.

Omelka, M., Gijbels, I. and Veraverbeke, N. (2009). Improved kernel estimation of copulas:

weak convergence and goodness-of-fit testing. Annals of Statistics, 37, 3023-3058.

Cao, R., Villar, J.M., Devia, A., Veraverbeke, N. Boucher, J-Ph. and Beran, J. (2009).

Modelling consumer credit risk via survival analysis. Statistics and Operations Research

Transactions, 33, 31-47.

Janssen, P., Swanepoel, J. and Veraverbeke, N. (2009). New tests for exponentiality against

new better than used in p-th quantile. Journal of Nonparametric Statistics, 21, 85-97.

Gaddah, A. and Braekers, R. (2009). Weak convergence for the conditional distribution

function in a Koziol-Green model under dependent censoring. Journal of Statistical

Planning and Inference, 139, 930-943.

Braekers, R. and Van Keilegom, I. (2009). Flexible modeling based on copulas in

nonparametric median regression. Journal of Multivariate analysis, 100, 1270-1281.

Massonnet, G., Janssen, P. and Duchateau, L. (2009). Modelling udder infection data using

copula models for quadruples. Journal of Statistical Planning and Inference 139, 3865-

3877.

Legrand, C., Duchateau, L., Janssen, P., Ducrocq, V. and Sylvester, R. (2009). Validation of

prognostic indices using the frailty model. Lifetime Data Analysis, 15, 59-78.

Goethals, K., Ampe, B., Berkvens, D., Laevens, H., Janssen, P. and Duchateau, L. (2009).

Modelling interval-censored clustered cow udder quarter infection times through the

shared gamma frailty model. Journal of Agricultural, Biological and Environmental

Statistics, 14, 1-14.

Molenberghs, G. (2009). Incomplete data in clinical studies: Analysis, sensitivity, and

sensitivity analysis (with discussion). Drug Information Journal, 43, 409-446.

Molenberghs, G. (2009). Incomplete data in clinical studies: Analysis, sensitivity, and

sensitivity analysis. Rejoinder. Drug Information Journal, 43, 447-448.

Mwambi, H., Ramroop, S., Shkedy, Z., and Molenberghs, G. (2008). An approach to

estimating the force of infection and the rate of recovery fom Respiratory Syncytial Virus

(RSV) data. Statistical Methods in Medical Research, 00, 000-000.

Goegebeur, Y., De Boeck, P., and Molenberghs, G. (2009). Person fit for test speededness:

Normal curvature, likelihood ratio tests, and empirical Bayes estimates. Methodology, 00,

000-000.

Beunckens, C., Sotto, C., Molenberghs, G., and Verbeke, G. (2009). A multifaceted sensitivity

analysis of the Slovenian Public Opinion Survey data. Applied Statistics, 58, 171-196.

==============================================

1 JCR : Journal Citation Reports (als afzonderlijke publicatie van de Science Citation Index en van de Social Sciences Citation Index, opgemaakt door het Institute for Scientific Information).

V=

Molenberghs, G., Burzykowski, T., Alonso, A., Assam, P., Tilahun, A., and Buyse, M. (2009). A

unified framework for the evaluation of surrogate endpoints in clinical trials. Statistical

Methods in Medical Research, 00, 000-000.

Laenen, A., Alonso, A., Molenberghs, G., Vangeneugden, T., and Mallinckrodt, C. (2009).

Using longitudinal data from a clinical trial in depression to assess the reliability of its

outcome scale. Journal of Psychiatric Research, 43, 730-738.

Sotto, C., Beunckens, C., Molenberghs, G., Jansen, I., and Verbeke, G. (2009). Marginalizing

pattern-mixture models for categorical data subject to monotone missingness. Metrika,

69, 305-336.

Gyselaers, W., Molenberghs, G., Van Mieghem, W., and Ombelet, W. (2009). Doppler

measurement of Renal Interlobar Vein Impedance Index in uncomplicated and pre-

eclamptic pregnancies: a pilot study. Hypertension in Pregnancy, 28, 23-33.

Laenen, A., Alonso, A., Molenberghs, G., and Vangeneugden, T. (2009). Reliability of a

longitudinal sequence of scale ratings. Psychometrika, 74, 49-64.

Decramer, M. and Molenberghs, G. (2009). Letter to the Editor: Does pharmacotherapy

reduce rate of decline of lung function in COPD? American Journal of Respiratory and

Critical Care Medicine, 179, 171-171.

Laenen, A., Alonso, A., Molenberghs, G., and Vangeneugden, T. (2009). A family of measures

to evaluate scale reliability in a longitudinal setting. Journal of the Royal Statistical

Society, Series A, 172, 237-253.

Tilahun, A., Maringwa, J.T., Geys, H., Alonso, A., Raeymaekers, L., Molenberghs, G., Van Den

Kieboom, G., Drinkenburg, P., and Bijnens, L. (2009). Investigating association between

behavior, corticosterone, heart rate, and blood pressure in rats using surrogate marker

evaluation methodology. Journal of Biopharmaceutical Statistics, 19, 133-149.

Verbeke, G. and Molenberghs, G. (2009). Arbitrariness of models for augmented and coarse

data, with emphasis on incomplete-data and random-effects models. Statistical Modelling,

00, 000-000.

Hill, R.C. Choate, C.J., Scott, K.C., and Molenberghs, G. (2009). Comparison of the

guaranteed analysis with the measured nutrient composition of commercial pet foods.

Journal of the American Veterinary Medical Association, 00, 000-000.

Ibrahim, J.G. and Molenberghs, G. (2009). Missing data methods in longitudinal studies: a

review (with discussion and rejoinder). Test, 18, 68-.

Kenward, M.G. and Molenberghs, G. (2009). Last Observation Carried Forward: a crystal ball?

Journal of Biopharmaceutical Statistics, 00, 000-000.

Rizopoulos, D., Verbeke, G., and Molenberghs, G. (2009). Multiple-imputation-based residuals

and diagnostic plots for joint models of longitudinal and survival data. Biometrics, 00,

000-000.

Gyselaers, W., Molenberghs, G., Mesens, T., and Peeters, L. (2009). Maternal hepatic vein

Doppler velocimetry during uncomplicated and preeclamptic pregnancy. Ultrasound in

Medicine and Biology, 00, 000-000.

Serroyen, J., Molenberghs, G., Aerts, M., Vloeberghs, E., De Deyn, P.P., and Verbeke, G.

(2009). Flexible estimation of serial correlation in linear mixed models. Journal of Applied


Jacobs, T., Straetemans, R., Molenberghs, G., Bouwknecht, A., and Bijnens, L. (2009). A

latent pharmacokinetic time profile to model dose-response survival data. Journal of

Biopharmaceutical Statistics, 00, 000-000.

Hens, N., Wienke, A., Aerts, M., and Molenberghs, G. (2009). The correlated and shared frailty

model for bivariate current status data: an illustration for cross-sectional serological data.

Statistics in Medicine, 28, 2785-2800.

= NM=

Guerra-Yi, M.E., Lorenzo-Luaces Alvarez, P., Faes, C., Galàn Alvarez, Y., and Molenberghs, G.

(2009). Spatial analysis of breast and cervix cancer incidence in small geographical areas

in Cuba, 1999-2003. European Journal of Cancer Prevention, 00, 000-000.

Jansen, I. and Molenberghs, G. (2009). Pattern-mixture models for categorical outcomes with

non-monotone missingness. Journal of Statistical Computation and Simulation, 00, 000-

000.

Creemers, A., Hens, N., Aerts, M., Molenberghs, G., Verbeke, G., and Kenward, M.G. (2009).

A sensitivity analysis for shared-parameter models for incomplete longitudinal outcomes.

Biometrical Journal, 00, 000-000.

Pryseley, A., Mintiens, K., Knapen, K., Van der Stede, Y., and Molenberghs, G. (2009).

Estimating precision, repeatability, and reproducibility from Gaussian and non-Gaussian

data: a mixed models approach. Journal of Applied Statistics, 00, 000-000.

Gyselaers, W., Molenberghs, G., Hanssens, M., and Peeters, L. (2009). Maternal renal

interlobar vein impedance index is higher in early- than in late-onset preeclampsia.

Ultrasound in Obstetrics and Gynecology, 00, 000-000.

Laenen, A., Alonso, A., Molenberghs, G., Vangeneugden, T., and Mallinckrodt, C. (2009).

Coping wit memory effect and serial correlation when estimating reliability in a

longitudinal framework. Applied Psychological Measurement, 00, 000-000.

Vangeneugden, T., Molenberghs, G., Laenen, A., Geys, H., Beunckens, C., and Sotto, C.

(2009). Marginal correlation in longitudinal binary data based on generalized linear mixed

models. Communications in Statistics, Theory & Methods, 00, 000-000.

Serroyen, J., Molenberghs, G., Verbeke, G., and Davidian, M. (2009). Nonlinear models for

longitudinal data. The American Statistician, 63, 378-388.

Faes, C., Molenberghs, G., Aerts, M., Verbeke, G., and Kenward, M.G. (2009). The effective

sample size and a novel small sample degrees of freedom method. The American

Statistician, 63, 389-399.

Molenberghs, G. and Verbeke, G. (2009). Longitudinal and incomplete clinical studies. Journal

of the Japanese Society of Computational Statistics, 22, 000-000.

Shkedy, Z., Lin, D., Molenberghs, G., Goehlmann, H., Talloen, W., and Bijnens, L. (2009).

Genomic biomarkers for depression: Feature-specific and joint biomarkers. Statistics in

Biopharmaceutical Research, 00, 000-000.

Molenberghs, G., Kenward, M.G., Verbeke, G., and Teshome Ayele, B. (2009). Pseudo-

likelihood estimation for incomplete data. Statistica Sinica, 00, 000-000.

Vangeneugden, T., Molenberghs, G., Verbeke, G., and Demétrio, C. (2009). Marginal

correlation from an extended random-effects model for repeated and overdispersed

counts. Journal of Applied Statistics, 00, 000-000.

Mallinckrodt, C.H., Detke, M.J., Prucka, W.R., Ruberg, S.J., and Molenberghs, G. (2009).

Design archetypes for phase II clinical trials in central nervous system disorders. Drug

Information Journal, 00, 000-000.


Considerations for using positive controls in phase II clinical trials of central nervous

system disorders. Drug Information Journal, 00, 000-000.


Considerations for comparing a test drug with standard of care in phase II clinical trials of

central nervous system disorders. Drug Information Journal, 00, 000-000.

Alonso, A., Laenen, A., Molenberghs, G., Geys, H., and Vangeneugden, T. (2009). Reliability of

single administered tests: a unified approach. Biometrics, 00, 000-000.

Creemers, A., Hens, N., Aerts, M., Molenberghs, G., Verbeke, G., and Kenward, M.G. (2009).

Generalized shared-parameter models and missingness at random. Statistical Modeling,

00, 000-000.

NN=

Bruckers, L., Serroyen, J., Molenberghs, G., Slaets, H., and Goeyvaerts, W. (2009). Latent-

class analysis of persistent disturbing behavior patients using longitudinal profiles. Applied


Wouters, K., Cortiñas Abrahantes, J., Molenberghs, G., Geys, H., Ahnaou, A., Drinkenburg,

W.H.I.M., and Bijnens, L. (2009). Correction for model selection bias using a modified

model averaging approach for supervised learning methods applied to EEG experiments.

Journal of Biopharmaceutical Statistics, 00, 000-000.

Molenberghs, G. and Kenward, M.G. (2010). Semi-parametric marginal models for hierarchical

data and their corresponding full models. Computational Statistics and Data Analysis, 54,

585-597.

Troxel, A., Lipsitz, S., Fitzmaurice, G., Ibrahim, J., Sinha, D., and Molenberghs, G. (2009). A

weighted combination of pseudo-likelihood estimators for longitudinal binary data subject

to nonignorable non-monotone missingness. Statistics in Medicine, 00, 000-000.

Assam, P., Tilahun, A., Alonso, A., and Molenberghs, G. (2009). Using earlier measures in a

longitudinal sequence as potential surrogate for a later one. Computational Statistics and

Data Analysis, 00, 000-000.

Molenberghs, G., Kenward, M.G., and Verbeke, G. (2009). Discussion of Lee, Y. and Nelder,

J.A.: Likelihood inference for models with unobservables: another view. Statistical

Science, 00, 000-000.

Laenen, A., Alonso, A. (2010). The functional living index – cancer: estimating its reliability

based on clinical trial data. Quality of Life Research, 00, 000-000.

Kasim, A., Lin, D., Van Sanden, S., Clevert, D., Bijnens, L., Gohlmann, H., Amaratunga, D.,

Hochreiter, S., Shkedy, Z., and Talloen, W. (2009). Informative or non-informative calls

for gene expression in microarray experiments. Statistical Applications in Genetics and

Molecular Biology.

Smeets, K., Opdenakker, K., Remans, T. Van Sanden, S., Van Belleghem, F., Semane, B.,

Horemans, N., Guisez, Y., Vangronsveld, J., Cuypers, A. (2009). Oxidative stress-related

responses at transcriptional and enzymatic levels after exposure to Cd or Cu in a

multipollution context. Journal of Plant Physiology, 166, 1982-92.

Boone, I., Van der Stede, Y., Bollaerts, K., Vose, D., Maes, D., Dewulf, J., Messens, W.,

Daube, G., Aerts, M. and Mintiens, K. (2009). NUSAP method for evaluating the data

quality in a quantitative microbial risk assessment model for Salmonella in the pork

production chain. Risk Analysis, 29, 502-517.

Cortiñas Abrahantes, J., Bollaerts, K., Aerts, M., Ogunsanya, V. and Van der Stede, Y. (2009).

Salmonella serosurveillance: Different statistical methods to categorize pig herds based

on serological data. Preventive Veterinary Medicine, 89, 59-66.

Namata, H., Welby, S., Aerts, M., Faes, C., Cortiñas Abrahantes, J., Imberechts, H.,

Vermeersch, K., Hooyberghs, J., Méroc, E., and Mintiens, K. (2009). Identification of risk

factors for the prevalence and persistence of Salmonella in Belgian broiler chicken flocks.

Preventive Veterinary Medicine, 90, 211-222.

Serroyen, J., Molenberghs, G., Aerts, M., Vloeberghs, E., De Deyn, P.P. and Verbeke, G.

(2009). Flexible estimation of serial correlation in nonlinear mixed models. Journal of

Applied Statistics, 00, 000-000.

Van Effelterre, T., Shkedy, Z., Aerts, M., Molenberghs, G., Van Damme, P. and Beutels, P.

(2009). Contact patterns and their implied basic reproductive numbers: an illustration for

varicella-zoster virus. Epidemiology and Infection, 137, 48-57.

Aerts, M., Hens, N., and Simonoff, J.S. (2009). Model selection in regression based on

presmoothing. Journal of Applied Statistics, 00, 000-000.

= NO=

Hens, N., Kvitkovicova, A., Aerts, M., Hlubinka, D., Beutels, P. (2009). Modelling distortions in

seroprevalence data using change-point fractional polynomials. Statistical Modelling, 00,

000-000.

Goeyvaerts, N., Hens, N., Ogunjimi, B., Aerts, M., Shkedy, Z., Van Damme, P., and Beutels, P.

(2010). Estimating infectious disease parameters from data on social contacts and

serological status. Journal of Royal Statistical Society, Series C, 59, 000-000.

Hens, N., Aerts, M., Faes, C., Shkedy, Z., Lejeune, O., Van Damme, P., and Beutels, P.

(2009). 75 years of estimating the force of infection. Epidemiology and Infection, 00,

000-000.

Van Heirstraeten, L., Cortiñas Abrahantes, J., Lammens, C., Lee, A., Harbarth, S.,

Molenberghs, G., Aerts, M., Goossens, H., and Malhotra-Kumar, S. on behalf of the

MOSAR WP2 study group (2009). Impact of a short period of pre-enrichment on detection

and bacterial loads of methicillin-resistant Staphylococcus aureus from screening

specimens, Journal of Clinical Microbiology, 47, 3326-3328.

Malhotra-Kumar, S., Cortiñas Abrahantes, J., Lammens, C., Molenberghs, G., Aerts, M.,

Goossens, H. on behalf of the MOSAR WP2 study Group. (2009). Evaluation of culture-

based approaches for rapid detection of glycopeptide-resistant enterococci: a randomised,

investigator-blinded study. Clinical Microbiology and Infection, 15, 58-58.

Van Heirstraeten, L., Cortiñas Abrahantes, J., Lammens, C., Lee, A., Harbarth, S.,

Molenberghs, G., Aerts, M., Goossens, H., Malhotra-Kumar, S. on behalf of the MOSAR

WP2 Study Group. (2009). Comparison of the impact of direct plating versus a short or

overnight pre-enrichment on detection of methicillin-resistant Staphylococcus aureus

from clinical specimens. Clinical Microbiology and Infection, 15, 208-208.

Sabiiti, W., Cortiñas Abrahantes, J., Lammens, C., Molenberghs, G., Aerts, M., Goossens, H.,

Malhotra-Kumar, S. on behalf of the MOSAR WP2 Study Group. (2009). Evaluation of

commercially available molecular and culturebased assays for rapid detection of

methicillin-resistant Staphylococcus aureus. Clinical Microbiology and Infection, 15, 440-

440.

Malhotra-Kumar, S., Cortiñas Abrahantes, J., Lammens, C., Molenberghs, G., Aerts, M.,

Goossens, H. on behalf of the MOSAR WP2 Study Group. (2009). Rapid detection of

extended-spectrum b-lactamaseproducing Enterobacteriaceae: a randomised,

investigator-blinded evaluation of culture-based approaches. Clinical Microbiology and

Infection, 15, 603-603.

Boone, I., Van der Stede, Y., Bollaerts, K., Messens, W., Vose, D., Daube, G., Aerts, M., and

Mintiens, K. (2009). Expert judgement in a risk assessment model for Salmonella spp. in

pork: The performance of different weighting schemes. Preventive Veterinary Medicine,

92, 224-234.

Sanchez, L., Cortiñas Abrahantes, J., Pelaez, O., Gutierrez, H., Concepción, D., and Van der

Stuyft, P ; (2009). Breteau index threshold levels indicating risk for dengue transmission

in areas with low aedes infestation. Tropical Medicine and International Health.

Doi:10.1111/j.1365-3156.2009.02437.x.

Hens, N., Goeyvaerts, N., Aerts, M., Shkedy, Z., Van Damme, P. and Beutels, P. (2009).

Mining social mixing patterns for infectious discease models based on a two-day

population survey in Belgium. BMC Infectious Diseases, 9, 5.

Ogunjimi, B., Hens, N., Goeyvaerts, N., Aerts, M. Van Damme, P. and Beutels, P. (2009).

Using empirical social contact data to model person to person infectious disease

transmission: an illustration for varicella. Mathematical Biosciences, 218, 80-87.

Hens, N., Minalu, G., Goeyvaerts, N., Aerts, M., Mossong, J., Edmunds, W.J. and Beutels, P.

(2009). Estimating the impact of school closure on social mixing behaviour and the

NP=

transmission of close contact infections in eight European countries. BMC Infectious

Diseases, 9, 187.

Robaeys, G., Nevens, F., Starkel, P., Colle, I., Van Eyken, P., Bruckers, L., Van Ranst, M.,

Buntinx, F. (2009). Previous intravenous substance use and outcome of liver

transplantation in patients with chronic Hepatitis C infection. Transplantation Proceedings,

589-594.

Bilau, M., De Henauw, S., Schroijen, C., Bruckers, L., Den Hond, E., Koppen, G., Matthys, C.,

Van De Mieroop, E., Keune, H., Bayens, W., Nelen, V., Van Larebeke, N., Willems, J.L.,

Schoeters, G. (2009). The relation between the estimation dietary intake of PCDD/Fs and

levels in blood in a Flemish population (50-65 years). Environment International, 35, 9-

13.

Den Hond, E., Govarts, E, Bruckers, L., Schoeters, G. (2009). Determinants of polychlorinated

aromatic hydrocarbons in serum in three age classes-methodological implications for

human biomonitoring, Environmental Research, 109, 495-502.

Vankrunkelsven, P., Kellen, E. Lousbergh, D., Cloes, E., Op de Beeck, L., Faes C., Bruckers, L.,

Mertens, R., Coeberg, J.W., Van Leeuwen, F.E., Buntinx F. (2009). Reduction in hormon

replacement therapy use and declining breast cancer incidence in the Belgian province of

Limburg, Breast Cancer Research and Treatment, 118, 425-432.

Croes, K., Baeyens, W., Bruckers, L., Den Hond, E., Koppen, G., Nelen, V., Van de Mieroop,

E., Keune, H., Dhooge, W., Schoeters, G. Van Larebeke, N. (2009). Hormone levels and

sexual development in Flemish adolescents residing in areas differing in pollution

pressure. International Journal of Hygiene and Environmental Health, 212, 612-625.

Koppen, G., Den Hond, E., Nelen, V., Van De Mieroop, E., Bruckers, L., Bilau, M., Keune, H.,

Van Larebeke, N., Covaci, A., Van De Weghe, H., Schroijen, C., Desager, K., Stalpart, M.,

Baeyens, W., Schoeters, G. (2009). Organochlorine and heavy metals in newborns:

results from the Flemish Environmental and Health Survey (FLEHS 2002-2006),

Environment International, 35, 1015-1022.

Liang, X., Jacobs, R., Hassan, B., Li L.M., Pauwels, R., Corpas, L., Couto Souza P., Martens, M.

Shahbazian, M., Alonso, A., and Lambrichts, I. (2009). A comparative evaluation of cone

bean computed tomography (CBCT) and multi-slice CT (MSCT)-Part I: on subjective

image quality. European Journal of Radiology (In press).

Bollaerts, L., Messens, W., Delhalle, L., Aerts, M., Van der Stede, Y., Dewulf, J., Quoilin, S.,

Maes, D., Mintiens, K. and Grijspeerdt, K. (2009). METZOON: Development of a

qualitative microbial risk assessment for human salmonellosis through household

consumption of fresh minced pork meat in Belgium. Risk Analysis, 29, 820-840.

Bollaerts, K., Messens, W., Aerts, M., Dewulf, J., Maes, D., Grijspeerdt, K. and Van der Stede,

Y. (2009). Evaluation of scenarios for reducing human salmonellosis through Household

consumption of fresh minced pork meat. Risk Analysis.

Lin, D., Shkedy, Z., Yekutieli, D., Dilba, G., Burzykowski, T., Goehlmann, H.W.H., De Bondt

A., Perera, T., Geerts, T., and Bijnens, L. (2009). Multiple contract test for detecting

monotonic dose-response relationship and FDR-adjusted confidence intervals for selected

parameters in a microarray setting. Online Journal of Bioinformatics, 10, 67-73.

Galecki, A.T., Chen, S., Faulkner, J.A., Ashton-Miller, J., Burzykowski, T. (2009). Statistical

power calculations for clustered continuous data. International Journal of Knowledge

Engineering and Soft Data Paradigms, 1, 40-48.

Valkenborg, D., Thomas, G., Krols, L., Kas, L., Burzykowski, T. (2009). A strategy for the prior

processing of high-resolution mass spectral data obtained from high-dimensional

combined fractional diagonal chromatography. Journal of Mass Spectrometry, 44, 516-

529.

= NQ=

Michiels, S., Le Maître, A., Buyse, M., Burzykowski, T., Maillard, E., Bogaerts, J., Vermorken,

J.B., Budach, W., Pajak, T.F., Ang, K.K., Bourhis, J., Pignon, J.P. on behalf of the MARCH

and MACH-NC collaborative groups (2009). Surrogate endpoints for overall survival in

locally advanced head and neck cancer: meta-analysis of individual patient data. Lancet

Oncology, 10, 341-350.

Burzykowski, T., Carpenter, J. Coens, C., Evans, D., France, L., Kenward, M., Lane, P. ,

Matcham, J., Morgan, D., Philips, A., Roger, J., Sullivan, B., White, I., Yu, L.M., of the PSI

missing data expert group (2009). Missing data: discussion points from the PSI missing

data expert group. Pharmaceutical Statistics (in press) DOI: 10.1002/pst.391.

Straczek A., Wannijn, J., Van Hees, M., Thijs, H. and Thiry, Y. (2009). Tolerance of hairy roots

of carrots to U chronic exposure in a standardized in vitro device. Environmental and

Experimental Botany 65, 82-89.

Jacobs, N., Claes, N., Thijs, H., Dendale, P. and De Bourdeaudhuij, I. (2009). Effect of a

tailored behaviour change programme in highly educated adults: a randomised controlled

trial. European Journal of Cardiovascular Prevention and Rehabilitation 16.

Aelvoet, W., Terryn, N., Francis, W., Redivo, M. and Faes, C. (2009). Miscoding: a threat to

the hospital care system. How to detect it ? Epidemiology and Public Health 57, 169-177.

Namata, H., Welby, S., Aerts, M., Faes, C., Cortiñas, J., Imberechts, H., Vermeersch, K.,

Hooyberghs, J. and Mintiens, K. (2009). Identification of risk factors for the prevalence

and persistence of salmonella in Belgian broiler chicken flocks. Preventive Veterinary

Medicine, 90, 211-222.

Faes, C., Aerts, M., Geys, H., Teuns, G. (2009). Modeling spatial learning in rats based on

morris water maze experiments. Pharmaceutical Statistics, 00,000-000 (Published online

Jan 2009).

Theeten, H., Hens, N., Aerts, M., Vandermeulen, C., Roelants, M., Hoppenbrouwers, K. and

Van Damme, P., Beutels, P. (2009). Caregiver concerns about the number of vaccine

injections and willingness to pay to reduce them. The Pediatric Infectious Disease Journal.

28, 61-63.

Theeten, H., Hens, N., Aerts, M., Vandermeulen, C., Roelants, M., Hoppenbrouwers, K. and

Van Damme, P., Beutels, P. (2009) Common attitudes about concomitant vaccine

injections for infants and adolescents in Flanders, Belgium. Vaccine. 27, 1964-1969.

Bilcke J., Van Damme P., Van Ranst M., Hens N., Aerts M., Beutels P. (2009). Estimating the

incidence of symptomatic rotavirus infections: a systematic review and meta-analysis.

PLoS ONE 4(6): e6060. doi:10.1371/ journal.pone.0006060

Boulet, G.A.V., Benoy, I.H., Depuydt, C.E., Horvath, C.A.J., Aerts, M., Hens, N., Vereecken,

A.J., Bogers, J.J. (2009). HPV16 load and integration as biomarkers for CIN2+ lesions in

HPV16-positive women. Cancer Epidemiology, Biomarkers & Prevention, 18, 2992–2999.

Sanchez, L., Perez, D., Cruz, G., Castro, M., Kouri, G., Shkedy, Z., Vanlerberghe, V., Van der

Stuyft, P. (2009). Intersectoral coordination, community empowerment and dengue

prevention: six years of controlled interventions in Playa Municipality, Havana, Cuba.

Tropical Medicine & International Health, 14, 1356-1364.

Lin, D., Shkedy, Z., Burzykowski, T., Talloen, W., Bijnens, L. (2009). A comparison of

procedures for controlling the false discovery rate in the presence of small variance

genes: a simulation study. Communications in Statistics-Simulation and Computation, 38,

2111-2122.

Lin, D., Shkedy, Z., Burzykowski, T. and Aerts, M., Goehlmann, H.W.H., De Bondt, A., Perera,

T., Geerts, T., and Bijnens L. (2009). Classification of trends in dose-response microarray

experiments using information theory selection methods. The Open Applied Informatics

Journal 000-000.

NR=

Tilahun, A., Lin, D., Shkedy, Z., Geys, H., Alonso, A., Peeters, W.P., Talloen, W., Drinkenburg

W., Goehlmann, H.W.H., Gorden, E., Bijnens L. and Molenberghs, G. (2009). Selection

and evaluation of genomic biomarkers for depression in a microarray setting. Journal of

Biopharmaceutical Research 000-000.

Overige wetenschappelijke publicaties

25 Overige artikels

Molenberghs, G. and Ortman, C. (2009). Surrogate endpoints: application in pediatric clinical

trials. In: Concepts and Applications of Pediatric Drug Development Mulberg, A., Silber,

S.A., and van den Anker, J.N. (eds.). New York: Wiley-Blackwell, 501-512. ISBN:

9780470169292.

Molenberghs, G., Beunckens, C., Jansen, I., Thijs, H., Verbeke, G. and Kenward, M.G. (2009).

Missing data. In: Handbook of epidemiology (2nd edition), I. Pigeot and W. Ahrends

(eds.) Heidelberg: Springer, 000-000. ISBN 3-540-00566-8, ISBN 978-3-540-00566-7

(2nd printing 2007).

Verbeke, G., Molenberghs, G. and Rizopoulos, D. (2009). Random effects models for

longitudinal data. In: Longitudinal research with latent variables. K. van Montfort, H. Oud,

and Al Satorra (Eds.). New York: Springer.

26 Artikels in proceedings

Laenen, A., Alonso, A., Moleberghs, G. and Vangeneugden, T. (2009). Estimating the

reliability of rating scales from clinical trial data. Proceedings of the 16th International

Meeting of the Psychometric Society. Cambridge, UK.

Vankerckhoven, V. Lammens, C., Chapelle, S., Vanderstraeten, A., Hens, N., Molenberghs, G.,

Goossens, H. (2009). Analysis of the gut microbiotica in irritable bowel syndrome patients

and healthy volunteers using selective media and real-time PCR. In Clinical Microbiology

and Infection. 19th European Congress of Clinical Microbiology and Infectious Diseases,

Helsinki, Finland, 16 May - 19 May 2009, P1249.

Vankerckhoven, V., van Voorden, S., Hens, N., Molenberghs, G., Goossens, H., Wiertz, E.

(2009). Activation of Toll-like receptor 2 and Toll-like Receptor 2/6 by lacobacilli. 19th

European Congress of Clinical Microbiology and Infectious Diseases, Helsinki, Finland, 15

– 19 May 2009.

Vankerckhoven, V., Lammens C., Chapelle S., Vanderstraeten A., Hens, N., Molenberghs G.,

Goossens H. (2009). Analysis of the gut microbiota of irritable bowel syndrome patients

and healthy volunteers using selective media and Real-Time PCR. 19th European

Congress of Clinical Microbiology and Infectious Diseases, Helsinki, Finland, 15 - 19 May

2009.

Loens K., Hens N., Ursi D., Goossens H., Aerts M., Ieven M. (2009). Application of an

expanded gold standard and latent class analysis to decide on the strategy for the

diagnosis of M.pneumoniae infections. 19th European Congress of Clinical Microbiology

and Infectious Diseases. Helsinki, Finland, 15 - 19 May 2009.

Creemers, A., Hens N., Aerts, M., Molenberghs, G., Verbeke, G., Kenward, M. (2009). A

sensitivity analysis in the shared parameter modeling framework. Proceedings of the 30th

annual conference of the international society for clinical biostatistics. August 23-27,

2009, University of Economics, Prague, Czech Republic.

= NS=

Del Fava, E., Shkedy, Z., Hens N., Faes, C., Bollaerts, K., Aerts, M., Manfredi, P., Teunis, P.,

Beutels, P. and Van Damme, P. (2009). Estimating the prevalence and the force of

infection of parvovirus B19 in Belgium using Bayesian hierarchical mixture models.

Second IBS Channel Network Conference, Ghent, Belgium, April 6-8, 2009.

Wallinga, J., Hens, N., Tamme, T. (2009). Who infected whom? Second IBS Channel Network

Conference, Ghent, Belgium, April 6-8, 2009.

Theeten, H., Roelants, M., Hens N. Vandermeulen, C., Boonen, M., Hoppenbrouwers, K.,

Depoorter, A.M., Van Damme, P. (2009). Timeliness of infant vaccination in Flanders

Belgium. Eurovaccine , Stockholm, 11 December 2009.

Theeten, H., Roelants, M., Hens, N., Aerts, M., Depoorter, A.-M., Vandermeulen, C., Boonen,

M., Hoppenbrouwers, K., Van Damme, P. (2009). Coverage of recommended vaccines in

infants in Flanders, Belgium, anno 2008. Proceedings of the 27th annual meeting of the

European society for paediatric infectious diseases. Brussels, Belgium, June 9-13, 2009.

Jacobs, N., Claes, N., Van Mierlo, J., Thijs, H., Dendale, P. and De Bourdeaudhuij, I. (2009).

Predictors of effectiveness of a tailored behaviour change programme with muliple

delivery modes, Moss-Morris, Rona and Yardley, Lucy (Ed;), Psychology & Health, 24, 67-

68.

Jacobs, N., Claes, N., Thijs, H., Dendale, P. and De Bourdeaudhuij, I. (2009). Effect of a

tailored behaviour change programme in highly educated adults: a randomised trial,

Kesteloot, H. and Ector, H. (Ed). Acta Cardiol, 64(1), 17-18.

Jacobs, N., Thijs, H., Dendale, P., De Bourdeaudhuij, I. and Claes, N. (2009). One year results

of a tailored behaviour change programme in highly educated adults: a randomised

controlled trials, Biddle, Stuart and Guldan, Georgia and Gans, Kim and Almeida, Marie

Daniel and French, Simone (ed.) International Society of behavioral Nutrition and Physical

activity ISBNPA’09, 235-235

27 Uitgaven van publicaties of proceedings als editor

Fitzmaurice, G., Davidian, M., Molenberghs, G. and Verbeke, G. (2009). Longitudinal Data

Analysis. Handbooks of Modern Statistical Methods. New York: Chapman & Hall/CRC.

28 Uitgaven van publicaties of proceedings als editor

Verbeke, G. and Molenberghs, G. (2009). Linear Mixed Models for Longitudinal Data

(Paperback Edition). New York: Springer.

Dmitrienko, A., Molenberghs, G., Christy Chuang-Stein, J.L. and Offen, W.W. (2009). Analysis

of clinical trial data using SAS: a practical guide. (Japanese Translation). Kodansya

Scientific & SAS Press.

3 Congressen en voordrachten

31 Organisatie van internationale wetenschappelijke congressen of zomerschool

Tomasz Burzykowski

Course `Generalized Linear (Mixed-effects) Models’. Polish National Group of the International

Society for Clinical Biostatistics, Krakov, Poland (1-3 juli 2009).

Ziv Shkedy

NT=

One-day Workshop `Stochastic Epidemic Models and Statistical Inference’. (Tom Britton).

Universiteit Hasselt, 28 mei 2009.

PO= sççêÇê~ÅÜíÉå=çé=áåíÉêå~íáçå~äÉ=ïÉíÉåëÅÜ~ééÉäáàâÉ=ÅçåÖêÉëëÉå

Noël Veraverbeke

15-24 augustus 2009. ISI2009, Durban, South Africa. Kernel estimation of copulas (21

augustus 2009)

27-28 november 2009. Nonparametric Statistics and Time Series, Brussel. Empirical likelihood

for non-smooth criterion functions (27 november 2009).

Geert Molenberghs

15-16 maart 2009. International Biometric Society Eastern North American Region, San

Antonio, Texas, USA. Round table discussion on “Survival Kit for the Scientific Publication

Jungle” (16 maart 2009).

15-18 maart 2009. International Biometric Society Eastern North American Region, San

Antonio, Texas, USA. Every missing not at random model has got a missing at random

counterpart with equal fit (17 maart 2009).

10-14 mei 2009. 5th Conference of the Eastern Mediterranean Region of the International

Biometric Society, Istanbul, Turkije. Incomplete data in clinical studies: analysis and

sensitivity analysis (13 mei 2009).

20-24 juli 2009. 27th European Meeting of Statisticians, Toulouse, France. Every missing not at

random model has got a missing at random counterpart with equal fit (23 juli 2009).

2-6 augustus 2009. Joint Statistical Meetings, Washington, D.C.. Every missing not at random

model has got a missing at random counterpart with equal fit (4 augustus 2009).

15-24 augustus 2009. ISI2009. Durban, South Africa. Interaction between biostatistics and

the medical profession (17 augustus 2009).

19-22 september 2009. Applied Statistics 2009, Ljubljana, Slovenia. Every missing not at

random model has got a missing at random counterpart with equal fit (20 september 2009).

21-22 september 2009. 6th International Meeting Recent Advances & Trends in Statistics

applied to clinical trials. Statistical methods in Biopharmacy. Incomplete data in clinical

studies: analysis and sensitivity analysis (22 september 2009).

Roel Braekers

20-24 juli 2009. 27th European Meeting of Statisticians, Toulouse, France. Cox regression

model for left-censored data with an extra cure fraction.

= NU=

Tomaz Burzykowski


Biometric Society, Istanbul, Turkije. A Bayesian qpproach to the identification of overlapping

peptides in a MALDI-TOF mass spectrum.

26 juni 2009. European Statistical Meeting on meta-Analysis, Basel, Switzerland. Meta-

analysis and validation of surrogate endpoints.

29 november – 3 december 2009. The IBS Australian Region Conference, Taupo, New

Zealand. A Bayesian approach to the quantification of overlapping peptides in a MALDI-TOF

mass spectrum.

Niel Hens

1-7 november 2009. Mathematisches Forschungsinstitut Oberwolfach, Deutschland.

Reconstructing transmission trees from partially observed epidemic trees: an illustration of

H1N1.

Auguste Gaddah

20-24 juli 2009. 27th European Meeting of Statisticians, Toulouse, France. A generalized

Koziol-Green model.

25-26 september 2009. Workshop on copula theory and its applications, Warsaw, Poland.

Testing under the extended Koziol-Green model.

Tetyana Kadankova

30 juni – 3 juli 2009. ASMDA XIII International Conference, Vilnius, Lithuania. Busy period,

time of first loss of a customer and the number of customers in M*/Gδ/1/B system.

Christel Faes

12-15 mei 2009. 3rd Annual Meting EPIZONE ‘Crossing borders’, Antalya, Turkije. Spatio-

temporal risk factor analysis for bluetongue in Northern Europe.

1-6 augustus 2009. Joint Statistical Meeting, Washington, USA. A spatio-temporal

transmission model to model the spread to bluetongue in Europe.

1-6 augustus 2009. Joint Statistical Meeting Washington, USA. Risk assessment in traffic

safety.

5-7 oktober 2009. European Transport Conference, Leeuwenhorst, Nederland. Spatial

modelling of risk in traffic safety on the road network.

Ziv Zhkedy


Biometric Society, Istanbul, Turkije. Modelling co-infection of HiV and HCV among injecting

drug users.

10-14 October 2009. European Monitoring Centre for Drugs and Drug Adiction (EMC/DDA), EU

Expert Meeting, Lisbon, Portugal. Co-infection at population level.

NV=

Marc Aerts

16-19 mei 2009. 19th European Congress of Clinical Microbiology and Infectious Diseases,

Helsinki, Finland. Statistics in clinical microbiology and infectious diseases: statistical

evaluation of diagnostic tests.

An Creemers

23-27 augustus 2009. 30th Annual Conference of the International Society for Clinical

Biostatstics, Prague, Czech Republic. A sensitivity analysis in the shared parameter modeling

framework.

Philippe Haldermans

8-10 juli 2009. The R user conference 2009. Agrocampus – Quest, Rennes, France.

LMMNorm : a package for the normalization of microarrays using linear mixed models.


Biostatistics, Prague, Czech Republic. Weights Ensemble Lasso: prediction using genetic

information when the number of samples is limited.

Saskia Litière

19-31 oktober 2009. 2nd International Workshop of the ERCIM Working Group on Computing

in Statistics, Limassol, Cyprus. Testing for misspecification in generalized linear mixed

models: a SAS macro.

Herbert Thijs

29 november – 3 december 2009. International Biometric Society, Australasian Meeting,

Taupo, New Zealand. The future of missing data.

Emanuele Del Fava

13-14 oktober 2009. Meeting of the ‘Drug related infectious diseases’ Modelling Network

group, Lisbon, Portugal. The co-infection between HCV and HiV: a joint modeling approach.

Annouschka Laenen

20-24 juli 2009. 16th International Meeting of the Psychometrics Society, Cambridge, UK.

Estimating the reliability of rating scales from clinical trial data.

Suzy Van Sanden


Biometric Society. Genomic biomarkers for a clinical outcome in early drug development

microarray experiments (invited speaker).

José Cortiñas


Biometric Society. Simplified modelling strategies for surrogate validation for multivariate

failure-time data.


Biostatistics, Prague, Czech Republic. Multivariate pairwise pseudo-likelihood techniques.

= OM=

Yovanna Castro

10-14 oktober 2009. European Monitoring Centre for Drugs and Drug Adiction (EMC/DDA)

Meeting for modelling data, Lisbon, Portugal. Survival analysis for time to hepatitis C infection

in injecting drug users.

Dan Lin

10-14 mei 2009. Eastern Mediterranean Region of the International Biometric Society,

Istanbul, Turkije. Dose-response modeling of gene expression data: testing and classification

of monotonic trends.

Tom Jacobs

10-14 mei 2009. Eastern Mediterranean Region of the International Biometric Society,

Istanbul, Turkije. A latent pharmacokinetic time profile to model dose-response survival

data.

21-23 oktober 2009. Non Clinical Biostatistics Conference, Boston, USA. A latent

pharmacokinetic time profile to model dose-reponse survival data.

33 Voordrachten in het buitenland op uitnodiging van instellingen of organisaties

=

Noël Veraverbeke

1-6 december 2009. Anton de Kom Universiteit van Suriname, Paramaribo. Applied Statistics

and Data Modeling (23 hrs).

=

Geert Molenberghs

Longitudinal and Incomplete Data (2009) . Recorded Webinar for Learn Stat., American

Statistical Association (4 sessions of 2 hrs) (with G. Verbeke).

=

Longitudinal and Incomplete Data (2009). Web based training program (with G. Verbeke).

21 januari 2009. Université Paris VI, Paris France. Statistics in drug development and

surrogate markers.

28-30 januari 2009. Erasmus Winter Programma, Erasmus Medical Center, Rotterdam,

Nederland. Missing values in clinical research (with H. Thijs).

The statistical evaluation of surrogate endpoints in clinical trials. Web based Training

Program.

19 maart 2009. MD Andersen Cancer Research Center, Houston, Texas. On the identifiability

of the random-effects distribution in mixed models.

4 april 2009. US National Academy of Sciences / Food and Drug administration oversight

committee for handling missing data in clinical trials. Incomplete data in clinical trials:

contributions to a taxonomy.

17 april 2009. Vereniging voor Ordinatie en Classificatie, Tilburg, Nederland. A latent variable

mixture model as a basis for senstivity analysis in incomplete longitudinal data.

ON=

8-12 juni 2009. University of Havana, Cuba. Longitudinal and incomplete data.

16-17 juni 2009. Société Française de Statistique, Parix, France. Longitudinal and incomplete

data.

8 juli 2009. Biometric Seminar, Osaka, Japan. Longitudinal and incomplete data in clinical

studies.

10-11 juli 2009. Osaka Unviersity Summer School, Osaka, Japan. Course on models for

longitudinal and incompelte data.

2 augustus 2009. Joint Statistical Meetings, Washington, D.C. Models for discrete repeated

measurements.

14-15 augustus 2009. ISI2009, Durban, South Africa. Course on models for longitudinal and

incomplete data.

2 december 2009. Statistics SIAC, at he Duke University Virtual Journal Club, Durham, North

Carolina. Incomplete and enriched data: analysis and sensitivity analysis.

10-11 december 2009. Deming Conference, Atlantic City, New Jersey. The statistical

evaluation of surrogate endpoints in clinical trials.

Niel Hens

30 november 2009. Universidade Eduardo Mondlane, Maputo, Mozambique. An introduction

to the R environment.

1-2 december 2009. Universidade Eduardo Mondlane, Maputo, Mozambique. Modelling

infectious diseases.

Christel Faes

10 maart 2009. University of Wollongong, Australia. The effective sample size and a small-

sample degrees of freedom method.

Ziv Shkedy

16-29 november 2009. University of Havana, Cuba. Modeling infectious diseases and

Bayesian Data Analysis.

25 oktober 2009. Jimma University, Ethiopië. Introduction to statistical computing and basic

bootstrap.

Marc Aerts

30 november 2009. Universidade Eudardo Mondlane, Maputo, Mozambique. An introduction

to the R environment.

1-2 december 2009. Universidade Eduardo Mondlane, Maputo, Mozambique. Modelling

infectious diseases.

= OO=

Paul Janssen

5-10 juli 2009. University of La Coruna, Spanje. Statistical inferencre for clustered interval-

censored data.

28-29 september 2009. Universitair Medisch Centrum, Rotterdam, Nederland.

Presentation 1: Basics of the parametric gamma frailty model.

Presentation 2: Parametric frailty models with other frailty densities.

Presentation 3: The semi-parametric gamma frailty model through EM and PL.

Suzy Van Sanden

9 september 2009. University of Linz, Austria. IWT: summary of pilot studies.

José Cortiñas

8-9 januari 2009. Meeting of the Working Group. Working Group on statistical analysis of

temporal spatial trends, Parma, Italië. Simulation to study design impact on analysis of

survey data.

10-21 december 2009. University of Havana, Cuba. Survival Analysis.

Nele Goeyvaerts

24 februari 2009. Lunch seminar at the London School of Hygiene and Tropical Medicine –

Infectious Disease Epidemiology Unit. Estimating infectious diseases parameters from data on

social contacts and serological status.

34 Presentatie van posters op internationale wetenschappelijke congressen

Qi Zhu

27 juni – 2 juli 2009. The ISMB/ECCB 2009 Conference, Stockholm, Sweden. A Bayesian

approach to the quantification of overlapping peptides in MALDI-TOF Mass Spectrum.

Setia Pramana

15-16 oktober 2009. 17th Annual meeting of the Belgian Statistical Society. Testing and

modeling of dose-response relationship in a pre-clinical microarray experiment.

Nele Goeyvaerts

1-6 augustus 2009. Joint Statistical Meetings, Washington D.C., USA. Estimating

transmission parameters for infectious diseases using social contact data.

2-4 december 2009. Epidemics2, Athens, Greece. Statistical inference on parovirus B19

immunology using data on social contacts and serological status.

Dirk Valkenborg

Mei 2009. ASMS, Philadelphia, USA. A model-based method estimating the relative

abundance in 18O-labeled mass spectra.

November 2009. SLS-Workshop, Groningen, Nederland. A model-based method estimating

the relative abundance in 18O-labeled mass spectrum.

OP=

Niel Hens

16-19 mei 2009. 19th European Congress of clinical microbiology and infectious diseases,

Helsinki, Finland. Analysis of the gut microbiotica in irritable bouwel syndrome patients and

healthy volunteers using selective media and real time PCR.

16-19 mei 2009. 19th European Congress of clinical microbiology and infectious diseases,

Helsinki, Finland. Application of an expanded gold standard and latent class analysis to decide

on the strategy for the diagnosis of M. pneumoniae infections.

9-13 juni 2009. 27th Annual meeting of the European Society for Paediatric Infectious

Diseases, Brussel. Coverage of recommended vaccines in infants in Flanders, bBlgium,

anno2008.

11 december 2009. Eurovaccine, Stockholm, Sweden. Timeliness of infant vaccination in

Flanders, Belgium.

11 december 2009. Eurovaccine, Stockholm, Sweden. Maternal antibodies against measles.

Herbert Thijs

1-6 augustus 2009. Joint Statistical Meetings, Washington, USA. NOCF, The future of missing

data.

21-23 october 2009. Non Clinical Biostatistics Conference, Boston, USA. NOCF, The future of

missing data.

4 Expert- en referee-opdrachten

41 Lidmaatschappen van editorial board van internationale tijdschriften

Noël Veraverbeke

- Associate editor of South African Statistical Journal (2009- )

- Nationaal correspondent voor International Association for Statistical Education (IASE)

Roel Braekers

- Associate editor ‘Statistica Neerlandica’ (2009- )

Geert Molenberghs

- Wiley Series in Probability and Statistics Editor (Editors: David J. Balding, Noel A.C.

Cressie, Nicholas I. Fisher, Iain M. Johnstone, J.B. Kadane, Geert Molenberghs, Louise M.

Ryan, David W. Scott, Adrian F.M. Smith, Jozef L. Teugels) (2003- )

- Co-editor of Biometrics (2007-2009)

- Co-editor of Biostatistics (2010-2012)

Marc Aerts

- Associate editor of Biometrics

- Associate editor of Statistical Modelling: An international journal

Ziv Shkedy


= OQ=

Tomasz Burzykowski

- Member of editorial board of Advances in Medical Sciences


Christel Faes

- Associate editor of Journal of Agricultural, Biological and Environmental Statistics

- Assosicate editor of Biometrics

42 Referee-opdrachten van publicaties op aanvraag van editorial board van

internationale tijdschriften

Noël Veraverbeke

• Computational Statistics and Data Analysis (2)

• Journal of Statistical Planning and Inference

• Mathematical Reviews (25)

• South African Statistical Journal (2)

Geert Molenberghs

• Biometrics (Editor: 250)

• Biostatistics

• Journal of Clinical Oncology

• Computational Statistics and Data Analysis

• Statistica Neerlandica

• Journal of Educational and Behavioral Statistics

• Book Proposal (Wiley, as advisor, 26)

• Book Proposal (Springer)

Marc Aerts

• Statistics in Medicine

• Journal of Statistical Computation and Simulation

• Statistica Sinica

• Journal of Applied Statistics

• Statistical Science

• Epidemiology and Infection

Roel Braekers

• Journal of Statistical Planning and Inference

• Annals of the Institute of Statistical Mathematics


Ariel Alonso

• Journal of the Royal Statistical Society-Series A

• Biometrics (3)


José Cortiñas

• Journal of Clinical Oncology (3)

• Biometrics

OR=

• Statistical Modeling

Tomasz Burzykowski

• Britsh Journal of Cancer

• Journal of Clinical Oncology (2)

• Biometrics (9)

• Journal of Applied Statistics

Adetayo Kasim

• Biometrics

Saskia Litière

• Statistical Modelling

Niel Hens

• Biostatistics

• Biometrics (2)

• International Journal of Biostatistics

• Journal of the Royal Statistical Society

• Mathematical Biosciences


Christel Faes

• Biometrics (4)

• Journal of Agricultural, Biological and Ecological Statistics (2)

• Computational Statistics and Data Analysis


• Preventive Veterinary Medicine

Herbert Thijs

• American Journal of Epidemiology

• Journal of Biopharmaceutical Statistics

Ziv Shkedy

• Statistical Applications in Molecular Biology

• Biometrics (9)


Suzy Van Sanden

• Biometrics

43 Referee-opdrachten van projecten, ingediend bij internationale onderzoeks-

programma’s

Noël Veraverbeke

• Jurylid voor de Belgian Science Policy Return Grants (20 mei 2009)

• Grant referee for the National Research Foundation (NRF) South Africa

• Project review for National Science Foundation (NRF) South Africa

= OS=

Geert Molenberghs

• Faculty member appointment (France: 1)

• Faculty member promotion (US: 1)

• Panellid by accreditatieaanvraag nieuwe opleiding (NVAO, Nederland: 1)

• Steering committee member of the European Science Foundation Research Networking

Programme on “Quantive Methods in the Social Sciences 2” (QMSS2) (2008-2012)

• Netherlands Research Council (NOW)(2)

• International Statistical Institute (ISF). Life Sciences, Committee Chair (2007-2009)

• International Biometric Society. Council Member (2010-2013)

• AERES review, Center for Research in Epidemiology and Population Health, Paris-Sud,

France

• ESF-Research Networking Programmes Proposals, Assessment (EU: 2)

• The Netherlands Organization for Health Research and Development (ZonMw) grant

proposal (the Netherlands: 1)

• Netherlands Organization for Health Research and Development (ZonMW: 1)

• US National Academy of Sciences/Food and Drug Administration Oversight Committee for

Handling Missing Data in Clinical Trials (US)

Marc Aerts

• Scientific expert for the European Food Safety Agency

• Reviewer for FWO-Vlaanderen

• Panel member of the Public Health Committee of FWO Vlaanderen

Paul Janssen

• Lid van de VLIR werkgroep onderzoek

• Lid van de FWO werkgroep onderzoeksbeleid

• Lid Stuurgroep Onderzoek en Ontwikkeling

• Lid van de Vlaamse Raad voor Wetenschapsbeleid

• UHasselt promotor voor het Steunpunt OOI (lid van de stuurgroep en het dagelijks

bestuur)

• Lid van het Bureau en stuurgroep Universitaire Ontwikkelingssamenwerking

• Vice rector onderzoek (2008-2012)

44 Lidmaatschappen van scientific committee van internationale congressen

Noël Veraverbeke

• AF Math Conference: Actuarial and Financial Mathematics Conference (international

conference), Brussel 4-5 februari 2010. Member of the scientific committee.

• Journées Internationales de Statistiques Théoriques et Appliquées 2010, Université Djillali

Liabes, Sidi Bel Abbés, Algeria, 10-12 april 2010.

• 58th ISI Conference, Dublin, 21-27 augustus 2011. Chairman of the General Topics

Committee.

• ICOTS8: International Conference on Teaching of Statistics, Ljubljana, Slovenia, 11-16 juli

2010. Organiser of Session “Less parametric methods in statistics”.

Geert Molenberghs

• XXX Conference of the International Society for Clinical Biostatistics, ISCB30, Prague,

Czech Republic, 23-27 augustus 2009. Chair of the Scientific Program Committee.

OT=

Christel Faes

• 10th Symposium on Public Health “Networks in Public Health: at the crossing of practice and

research” Belgian Association of Public Health (11 December 2009). Member of the

Scientific Committee.

Ziv Shkedy

• 5th Conference of the Eastern Mediterranean Region of the International Biometric Society,

Istanbul, Turkije, 10-14 mei 2009. Organiser of a session “Microarray analysis in

medicine”.

45 Referee-opdrachten t.a.v. internationale congressen

/

46 Lidmaatschappen van wetenschappelijke commissies in binnen- en buitenland

Noël Veraverbeke

• Lid van de Hoge Raad voor Statistiek (benoemd op 8 november 1998)

• Lid van het Wetenschappelijk Comité van de enquête 2001 (2001- )

• Lid van de Scientific Council van Eurandom, Eindhoven, Nederland (2004-2010)

• Lid van de stuurgroep van de FWO Wetenschappelijke Onderzoeksgemeenschap Wiskunde

(1996- )

• Lid van de jury van de Vlaamse Wiskunde Olympiade (1985- ) Voorzitter (2007- )

• Vertegenwoordiger van FWO-Vlaanderen in de vergaderingen van Mathematics

Representatives of the European Union (Paris 2003, Stockholm 2004, Berlin 2005, London

2006, Oslo 2007, Valencia 2008)

• Jurylid Prijs Ontwikkelingssamenwerking (2005- )

• Verantwoordelijke voor het Outreach Programme van de Bernoulli Society (2005- )

• Lid van de VLIR werkgroep Internationalisering (2006- )

Geert Molenberghs

• Lid van de Wetenschappelijke Commissie Wiskunde van het FWO (2003-2010)

• Lid van de Commissie voor International Wetenschappelijke Contacten van het FWO (2003-

2010)

José Cortiñas

• Working group on statistical analysis of temporal and spatial trends.

Paul Janssen

• President van de Belgische Vereniging voor Statistiek

5 Verwerving van extern gefinancierde onderzoeksprojecten

51 Verwerving van onderzoeksprojecten als projectleider met internationale

participatie

Niel Hens

WHO grant on collecting social contact data in South-East Asia

= OU=

Christel Faes

EPIZONE (EP7 networking), Establishing the transmission dynamics of Bluetongue serotype 8

and entomological aspects in Northern Europe.

Project Leader: Yves Van der Stede (CODA)

External expert: UHasselt (Christel Faes)

Budget (UHasselt): 6000€

Ziv Shkedy

Vaccine preventable diseaeses modelling in the European union and EEA/EFTA countries:

Forecasting the effect of introducing a new vaccine in a national/regional program, Grant

2009/002, European Centre of Disease Control and Prevention.

VLIR-UOS project: North-South-South with partners:

Universiteit Hasselt

Universiteit Gent

Jimma University, Ethiopia

University Eduardo Mondlane, Mozambique

Aim: Course development for master programs in the South

52 Verwerving van onderzoeksprojecten als deelnemer met internationale

participatie

53 Verwerving van binnenlandse (nationaal of regionaal) onderzoeksprojecten

Christel Faes

� SME-feasibility project (IWT), Development of risk management tools for surveillance of

emerging animal diseases (RISKEMERG). Industrial Partner: Vose Software (project

leader: Koen Mintiens), Research Partner: I_Biostat (Project leader: Christel Faes), Budget

(Uhasselt): 35000€

� FWO Nieuw onderzoeksproject 2009 (Commissie Wiskunde), Spatio-temporal modeling of

infectious diseases. Promotor: Christel Faes, Co-Promotor: Marc Aerts en Matt Wand.

Niel Hens

Evidence-based Vaccinology (2009-2012).

Tomasz Burzykowski

Statistical analysis of isotope-labeled MALDI-TOF mass spectra. New Initiative Project funded

by Hasselt University Special Research Funds.

Saskia Litière

� EFSA Development of a SAS Macro to import, analyse and visualize data from the DG-

SANCO Rapid Alert System for Food and Feed Safety as a tool for “early warning”.

� EFSA Request for assistance in development of statistical analyses of methods for

evaluation of data on antimicrobial resistance in zoonotic agent isolates from animals and

food.

� EFSA Request for assistance in statistical evaluation of the achievements by Member States

of the EU Salmonella reduction targets in animal populations.

OV=

Ziv Shkedy

Cell line based compound prioritization and response prediction, IWT.

Censtat dienstverlening

In 2009 werd met volgende instellingen/bedrijven samengewerkt: Amsterdam Molecular

Therapeutics (AMT), Asture BVBA, Belgian Association for Cardio-Thoracic Surgery (BACTS),

Centrum voor Alcohol- en andere drugproblemen (CAD), Eli Lilly, European Food Safety

Authority (EFSA), IM Associates, Janssen Pharmaceutica NV, Johnson & Johnson

Pharmaceutical Research and Development L.L.C., KOPP, KULeuven, LOOA (Limburgs Overleg

Onderwijs Arbeid), Mars Belgium, Mars UK Limited, Openbare Vlaamse afvalstoffen

Maatschappij (OVAM), Provinciaal Steunpunt Arbeidszorg, Provinciale Hogeschool Limurg

(PHL), Provincie Limburg, Rekenhof, RIZIV, Sanofi-Aventis Recherche & Développement,

Schwarz Biosciences, Tibotec bvba, UCB Pharma sa, Universitair Ziekenhuis Maastricht,

University of Pisa, Virga Jesse Ziekenhuis, Vlaams Instituut voor Technologisch Onderzoek

(VITO), Vlaamse Interuniversitaire Raad (VLIR), Vrije Universiteit Brussel (VUB), Wake Forest

Unviersity, Wetenschappelijk Instituut Volksgezondheid, XIOS Hogeschool, Ziekenhuis Oost-

Limburg (ZOL)

6 Prijzen, vermeldingen, gerealiseerde toepassingen

61 Behaalde wetenschappelijke prijzen

Geert Molenberghs

2009 Excellence in Continuing Education Award of the American Statistical Association for

Course on Discrete Londigitudinal Data, presented by Verbeke, G. and Molenberghs, G.

at the Joint Statistical Meetings, Denver, Colorado (04/08/2008). Awarded at the Joint

Statistical meetings in Washintgon, District of Columbia, XX/08/2009.

2008-2009: Belgian Francqui Chair, Universiteit Antwerpen.

Niel Hens

Scientific chair “Evidence-based Vaccinology” Universiteit Antwerpen.

Promotors: Philippe Beutels end Pierre Van Damme (Universiteit Antwerpen)

Emanuele Del Fava

First Prize for student paper competion at the 2nd IBS Channel Network Conference, Gent.

Christel Faes

Prijs “Laureaat van de VEE 2009”: 3-jaarlijkse prijs uitgereikt door de Vlaamse Vereniging

voor Veterinaire Epidemiologie en Economie, ter bekroning en stimulering van een wezenlijke

bijdrage in het domein van fundamenteel en/of toegepast onderzoek inzake veterinaire

epidemiologie.

= PM=

7 Samenwerking met andere wetenschappelijke instellingen en onderzoekers

72 Verblijf van buitenlandse onderzoekers aan de UHasselt

Wondwossem Kassahun, Jimma University, Ethiopia

1 januari – 31 maart 2009; onderzoek

Financiering: VLIR – Jimma

Andrea Troxel, University of Pennysylvania, Philadelphia, USA

15-17 januari 2009; onderzoek

Financiering: Uhasselt

Djork-Arné Clevert, Johannes Kepler University, Linz, Austria

13 februari 2009; onderzoek


Marek Omelka, Charles University, Prague, Czech Republic

20 februari 2009; onderzoek

Financiering: IUAP

Frederico Zanqueta Poleto, University of São Paulo, Brazil

1 mei – 31 juli 2009; onderzoek


Yehenew Getachew, Jimma University, Ethiopia

16 maart – 31 mei 2009: onderwijs survival

Financiering: VLIR-Jimma

Befekadu Gashaw, Jimma University, Ethiopia

16 maart – 31 mei 2009; onderwijs survival


Fentaw Abegaz, University of Addis Abeba, Ethiopia

16 maart – 31 mei 2009; onderwijs survival


Demetrio Clarice, ESALQ, Universidade de São Paulo, Brazil

2 mei – 31 mei 2009 ; cursus Topics in Biometry

Financiering: UHasselt

Khangelani Zuma, Human Sciences Research Council, Pretoria, South Africa

25 mei – 5 juni 2009; cursus Topics in Epidemiology

Financiering: UHasselt

Jan Swanepoel, North West University, Potchefstroom, South Africa

29 maart – 5 april 2009; onderzoek

Financiering: Uhasselt en North West University

Tom Britton, Stockholm University, Sweden

28-29 mei 2009; onderzoek

PN=


Rafica Razac, Unviersity Edwardo Mondlane, Mapato, Mozambique

25 mei – 7 juni 2009; onderzoek

Financiering: VLIR-Mozambique

Legesse Negash, Jimma University, Ethiopia

20 september – 2 december 2009; onderwijs inference


Yilma Tefera, Addis Ababa University, Ethiopia



Zeytu Gashaw, Hawassa University, Ethiopia



Mekonnen Tadesse, Addis Ababa University, Ethiopia

20 september – 2 december 2009, onderwijs linear models


Laekemariam Berhe, Hawassa University, Ethiopia

20 september – 2 december 2009; onderwijs linear models


Marek Omelka, Charles University, Prague, Czech Republic

22 juni – 6 juli 2009; onderzoek

Financiering: IUAP

Ofer Harel, University of Connecticut, Storrs, USA

11-12 december 2009; onderzoek

Financiering, Uhasselt

Juan Carlos Pardo Fernandez, University of Vigo, Spain

26-27 november 2009; onderzoek


Tertius de Wet, Universiteit van Stellenbosch, South Africa

13-15 december 2009; onderzoek


73 Gemeenschappelijk verricht onderzoek

Jan Swanepoel (North-West University, Potchefstroom, Zuid Afrika)

Paul Janssen en Noël Veraverbeke

Resampling and goodness-of-fit

19-27 januari 2008: P. Janssen en N. Veraverbeke in Potchefstroom

BOF financiering

= PO=

Stéphane Loisel en Romain Biard (Université de Lyon 1, France) and Claudio Macci (University

of Rome, Tor Vergata)

Noël Veraverbeke

Risk Theory

Individueel akkoord

Ingrid Van Keilegom (UCL)

Noël Veraverbeke

Empirical likelihood with non smooth criterion function

Individueel akkoord

Elisa Molanes (University Carlos III Madrid, Spain)

Noël Veraverbeke

Empirical likelihood

Individueel akkoord

Irène Gijbels (KULeuven) en Marek Omelka (Charles University, Prague)

Noël Veraverbeke

Copula estimation

IAP Network

22 juni – 6 juli 2009: Marek Omelka in UHasselt

Paul Markel (Minot State University, USA)

Roel Braekers

Cox’s regression model for left-censored data with an extra cure fraction

Individueel akkoord

Jacobo de Uña Alvarez (University of Vigo, Spain)

Noël Veraverbeke

Koziol-Green model

Spanish Grant MTM2008-03129.

13-16 september 2009: Noël Veraverbeke in Vigo

Ricardo Cao and Ignacio Lopez de Ullibarri (University of La Coruña, Spain)

Paul Janssen

Fitting frailty models via transformations: the continuous case

Individueel akkoord

Jimma University, Jimma, Ethiopia

Paul Janssen, Noël Veraverbeke, Ziv Shkedy

IUS samenwerking

Diverse bezoeken

10-18 september 2009: Paul Janssen in Jimma

Oktober 2009: Ziv Shkedy in Jimma

VLIR-UOS

Philippe Beutels, Joke Bilcke, Olivier Lejeune, Benson Ogunjimi, Pierre Van Damme (Centre for

the Evaluation of Vaccination WHO Collaborating Centre for Control and Prevention of

Viral Hepatitis Unit of Epidemiology and Social Medicine University of Antwerp, Antwerp,

Belgium)

Niel Hens, Marc Aerts, Nele Goeyvaerts

Modelling Infectious Diseases: Hepatitis A Outbreak Modelling; Modelling Varicella Zoster

Virus; ESEN2-project; Polymod-project'

SBOSIMID, POLYMOD

Marieke Deregt and Marc Bonten (Utrecht University, The Netherlands)

Hospital infections and factors determining the spread of pathogens''

Niel Hens, Nele Goeyvaerts, Yovanna Castro

SBOSIMID

PP=

John Edmunds, Nigel Gay and Alessia Melagaro (Health Protection Agency, London, UK)

Elucidation on differences in the sero-epidemiology of VZV and B19 in five European

countries.

Niel Hens, Marc Aerts, Nele Goeyvaerts

22-26 februari 2009: Niel Hens en Nele Goeyvaerts in London

SBOSIMID

Paul Eilers (Utrecht University, The Netherlands) and Carlo Giovanni Camardo (Max Planck

Institute for Demographic Research, Rostock, Germany.).

Niel Hens

Estimating the contact matrix using tensor-product B-splines

SBOSIMID

Stefan Flassche, John Edmunds, (Health Protection Agency, UK), H1N1 in the early stages in

Europe'

Niel Hens

Individueel akkoord

Thomas House, Matt Keeling, (University of Warwick, Warwick, UK), School closure and

pandemic influenza

Niel Hens

Individueel akkoord

Slavik Koval, Odo Diekmann and Marc Bonten (Utrecht University, The Netherlands)

Estimating the delay in stochastic epidemic models

Niel Hens

SBOSIMID

Andrea Kvitkovicova, David Hlubinka (Charles University, Prague), Modelling Distortions in

Seroprevalence Data Using Change-point Fractional Polynomials.

Niel Hens, Marc Aerts

Indiviodueel akkoord

Gail Potter, Ira Longini, Betz Halloran, Mark Handcock (University of Washington, Seattle, US),

Estimating network structures from egocentric data

Niel Hens

SBOSIMID

Jeff S. Simonoff (Leonard N. Stern School of Business, New York University), Model Selection

after Presmoothing

Niel Hens

Individueel akkoord

Thierry Van Effelterre (GlaxoSmithKline Biologicals, Rixensart, Belgium), Network models to

assess infectious disease spread

Niel Hens

Individueel akkoord

Jacco Wallinga (University of Utrecht, The Netherlands), Inferring epidemic trees from partially

observed data

Niel Hens

Individueel akkoord

Andreas Wienke (Martin-Luther-Universität Halle-Wittenberg), Modelling bivariate current

status data

Niel Hens

Individueel akkoord

Elizabeth Halloran and Ira Longini, University of Washington, Seattle

Niel Hens

Stochastic modelling of pandemic influenza.

= PQ=

22-24 juni 2009: Niel Hens in Seattle

Anton de Kom Universiteit van Suriname

Paul Janssen, Noël veraverbeke, Roel Braekers

Applied Statistics and Data Modelling

VLIR-UOS

1-6 december 2009: Noël Veraverbeke in Paramaribo

Andreas Wienke (Martin-Luther-Universität Halle, Wittenberg, Duitsland)

Paul Janssen

Frailty models

Individueel akkoord

3-6 mei 2009: Paul Janssen in Halle

Patrick Cras, Bart Van Everbroeck, Pierre Van Damme, Philippe Beutels, Koen Van Herck

(Universiteit Antwerpen), Dirk Berkvens (Instituut voor Tropische Geneeskunde), Claude

Saegerman (Universiteit Luik), Koen Mintiens, Stefan Roels (Centrum voor Onderzoek in

de Diergeneeskunde en Agrochemie).

Marc Aerts

Diverse FWO grants

SBO-IWT grant “Simulation models of infectious disease transmission and control processes

(SIMID), with applications to five major health policy issues in Flanders”, Gaelle Boulet,

John-Paul Bogers, Kris Verstreken

Marc Aerts

SBO-IWT Grant

Koen Mintiens, Ides Boone, Yves Van der Stede (Centrum voor Onderzoek in de

Diergeneeskunde en Agrochemie), Georges Daubes, Laurent Delhalle (Universiteit Luik),

Jeroen Dewulf, Dominiek Maes (Universiteit Gent), Koen Grijspeerdt (Instituut voor

landbouw- en Visserijonderzoek)

Marc Aerts

Project FOD Volksgezondheid

Europees project POLYMOD: Pierre Van Damme, Philippe Beutels (Universiteit Antwerpen),

Peter Teunis, Jacco Wallinga (RIVM) + 14 European partner research institutes.

Marc Aerts

Europees Project POLYMOD

Methusalem project on Vaccine and Infectious Diseases (Antwerp University and Hasselt

University): Herman Goossens, Greet Ieven, Vanessa Vankerckhoven, Katherine Loens.

Marc Aerts

Methusalem Project on Vaccine and Infectious Diseases (Antwerp University and Hasselt

University)

University Eduardo Mondlane, Mozambique

Marc Aerts

IUC Programme ‘Desafio’ (Reproductive Health and AIDS/HIV)

Lucas Wiessing (European Monitoring Centre for Drugs and Drug Adiction) and Julius Centre

for Health Sciences and Primary Carl

Mirjam Kretschman, University Medical Centre Utrecht

Yovanna Castro

Amsterdam Cohort Study

10-14 oktober 2009: Yovanna Castro in Utrecht

P. Manfredi, University of Pisa, Italy

Emanuele Del Fava, Ziv Shkedy

Infectious diseases

November 2009: Emanuele Del Fava in Pisa

PR=

Koen Mintiens (Vose Consulting Belgium), Yves Van der Stede (VAR Belgium), Estalle Méroc

(VAR, belgium), Armin Elbers (CVI, the Netherlands), Alinde de Koeijer (CVI, the

Nederlands), Christoph Staubach (FLI, Germany), Franz Conraths (FLI, Germany), Helène

Guis (CIRAD, France)

Christel Faes

Stuyding the spatio-temporal spread of infectious diseases: application on bluetongue

virus in Belgium, the Netherlands and Germany

EPIZONE

10-11 februari 2009: Christel Faes in Parijs

Estelle Méroc, Yves van der Stede and Koen Mintiens (Veterinary and Agrochemical Research

Centre, Belgium)

Christel Faes

Herd-prevalence estimation based on aggregate testing of animals

Cunsulting and FWO mandaat (Christel Faes)

Pulak Ghosh (India)

Christel Faes

Semiparametric Bayesian approach to multivariate cross-over designs

FWO mandaat (Christel Faes)

Matt Want en John Ormerod (University of Wollongong, Australia)

Christel Faes

Variational approximation and missing data

FWO mandaat (Christel Faes)

4 maart-3 april 2009: Christel Faes in Wollongong

Paddy Faddington, Open University, UK.

Ziv Shkedy

Marissa Lassere & Kent Johnson

Tomasz Burzykowski

Surrogate endpoint validation methods

Australian grand and censtat

9 oktober 2009: Marissa Lassere en Kent Johnson in Uhasselt

4-11 december 2009: Tomasz Burzykowski in New South Wales University, Sidney,

Australia

Sepp Hochreiter, Ulrich Bodenhofer, Djork Clevert Johannes Keppler University, Linz, Austria

Cell line based compound prioritization and response prediction. Conditional FARMS for

meta Analysis of gene expression. Assessment of probe reliability

Dan Lin, Ziv Shkedy, Suzy Van Sanden, Adetayo Kassim

IWT Project (Linz-Janssen Pharmaceutica – Uhasselt)

1-30 september 2009: Adetayo Kassim in Linz

7-10 september 2009: Suzy Van Sanden in Linz

7-8 september 2009: Ziv Shkedy in Linz

Mike Kenward (London School of Hygiene and Tropical Medicine, UK)

Marc Aerts, Geert Molenberghs, Herbert Thijs, Niel Hens, Ivy Janssen, An Creemers

Incomplete clinical trial data

IAP Network and ESRC Grant

Diverse bezoeken

Geert Verbeke, Iven Van Mechelen, Francis Tuerlinckx, Paul De Boeck, Dirk Smits (KULeuven)

Geert Molenberghs

Logistic models in item response theory

Individueel akkoord

= PS=

Michael Kenward (London), Raymond Caroll (Texas A&M University), Craig Malinckrodt (Eli

Lilly, Indianapolis, USA)

Geert Molenberghs, Caroline Beunckens, Ivy Jansen, Cristina Sotto

Missing data in clinical trials

Individueel akkoord

Carmen Cadarso Suarez (Santiago de Compostela, Spain)

Geert Molenberghs, Helena Geys, Ariel Alonso, Christel Faes

Neuro synchronization

Grant BMF2005-00818 (Spain)

Jacco Wallinga (Utrecht)

Niel Hens, Ziv Shkedy

Epidemic trees

Individueel akkoord

Luc Bijnens (Janssen Pharma)

Dan Lin

Microarray data

Individueel akkoord

George Daube (UL), Lieven De Zutter (UG), Koen Grijspeerdt (CLO), Koen Mintiens (CODA),

Herman Van Oyen (WIV)

Kaatje Bollaerts, Marc Aerts, Ziv Shkedy

Individueel akkoord

Dani Yekutieli, (Tel-Aviv University, Israel)

Dan Lin, Tomasz Burzykowski, Ziv Shkedy

Microarray experiments

Individueel akkoord

University of Havana, Cuba

Geert Molenberghs, José Cortiñas, Niel Hens

Training and Research program in medical statistics and bioinformatics

20-30 juni 2008: José Cortinas in Cuba

19-29 mei 2008: Niel Hens in Cuba

VLIR-UOS

Edward Ip (Wake Forest University, Winston-Salem, USA)

Geert Molenberghs

Logistic models in item response theory

Individueel akkoord

Yuri Goegebeur (University of Southern Denmark, Odense)

Geert Molenberghs

Item response theory

Individueel akkoord

Clarice Demétrio en Afriano Vieira (Sao Paulo State University, Brasil)

Geert Molenberghs, Tony Vangeneugden, Geert Verbeke

Combined longitudinal-overdispersed models

Individueel akkoord

Koen Mintiens (Vose Consulting Belgium), Yves Van der Stede (VAR Belgium), Estalle Méroc

(VAR, Belgium), Armin Elbers (CVI, the Netherlands), Alinde de Koeijer (CVI, the

Nederlands), Christoph Staubach (FLI, Germany), Franz Conraths (FLI, Germany), Helène

Guis (CIRAD, France)

Estelle Méroc, Yves van der Stede and Koen Mintiens (Veterinary and Agrochemical Research

Centre, Belgium)

Christel Faes

PT=

Bluetongue infection

Consulting en FWO

Wim Talloen, Anne De Bondt, Hinrich Goehlmann, Luc Bijnens (Janssen Pharmaceutica)

Arthur Gitome, Setia Pramana, Suzy Van Sanden, Ziv Shkedy, Dan Lin, Adetayo Kassim

Microarrays

Individueel akkoord

Dhammika Amaratunga (Johnson & Johnson, Raritan, New Jersey, USA)

Philippe Haldermans

Microarray analysis

Individueel akkoord

11-22 augustus 2008: Philippe Haldermans in Raritan

= PU=

Activiteitenverslag

- Voordrachten op nationale of regionale congressen, studiedagen, symposia,

workshops

Noël Veraverbeke

- 22 oktober 2009. Katholieke Universiteit Leuven, Campus Kortrijk. Gastvoordracht

Wetenschap en Technologie. Meetkundige (On)waarschijnlijkheden. Van Naaldje tot

….

Geert Molenberghs

- 12 januari 2009. K.U.Leuven. Informal brain storming. Getting acquainted session

ESAT-SCB/bioi & I-H-L-Biostat.

- 13 januari 2009. UHasselt. Applying to FWO.

- 16 and 23 januari en 27 maart 2009. Uhasselt. Joint Reading group I-Biostat/Centraal

Bureau voor Statistiek.

- 17 februari 2009. K.U.Leuven. OT/09/041

- 18 februari 2009. Universiteit Antwerpen. Het wetenschappelijk interdiciplinair

seminarie. Repeated measures in medical statistics.

- 20 februari 2009. Universiteit Antwerpen. Course: Biostatistics for PhD Students,

Missing Data.

- 23 februari 2009. Universiteit Antwerpen. Belgian Franqui Chair. Inaugural lecture:

The applied statistical scientist in a high-profile academic environment.

- 5, 12, 26, 30 maart 2009. Universiteit Antwerpen. Belgian Franqui Chair Lectures.

- 26 maart 2009. Louvain-La-Neuve. IUAP Meeting.

Every missing not at random model has got a missing at random counterpart with

equal fit.

- 24 april 2009. Uhasselt. Scientific meeting I-Biostat-KIZOK.

Introduction, surrogate markers, longitudinal and incomplete data

- 4 mei 2009. Uhasselt. Sensitivity Analysis Working Group.

Pseudo-likelihood and MAR.

- 29 mei 2009. K.U.Leuven. Leuven Statistical Day.

On the identifiability of the incomplete-data models and random effects.

- 4 september 2009. K.U.Leuven. Steunpunt Welzijn, Volksgezondheid en Gezin.

Statistical background to SWVG.

- 6 oktober 2009. UHasselt. Sensitivity Analysis Working Group.

Pseudo-likelihood estimation for incomplete data.

- 8 oktober 2009. Brussel. FWO Expert panels. Paneldiscussie over peer-review.

- 10 november 2009. Universiteit Antwerpen.

The State of the Art Lectures in Biomedicine. Statistical methods in (pre)clinical trials.

- 15 oktober 2009. 17th Annual Meeting of the Belgian Statistical Society. Lommel. On

the indentifiability of the random-effects distribution in mixed models.

- 23 november 2009. K.U.Leuven. Longitudinal Data Analysis Working Group I-Biostat.

On the indentifiability of the random-effects distribution in mixed models.

- 27 oktober 2009. Visit of a Latin-American delegation to K.U.Leuven, Belgium.

I-Biostat and its activities.

- 9 november 2009. K.U.Leuven. Longitudinal Data Analysis Working Group.

PV=

A model family for hierarchical data with combined normal and conjugate random

effects.

- 20 november 2009. K.U.Leuven. IUAP.

Workshop on Modelling Association and Dependence in Complex Data. Work package

3: incomplete data.

- 26 november 2009. Uhasselt. Sensitivity Analysis Working Group. Shared-parameter

models and missing at random.

Niel Hens

- 18 september 2009. K.U.Leuven. Data Mining in Leuven Workshop, Arenberg Doctoral

School.

Using tree based methods and support vector machines to identify dengue

hemorrhagic fever cases based on symptoms and blood tests.

- 23 february 2009. London School of Hygiene and Tropical Medicine.

Infectious disease parameters for ttransmission models: a modern statistical

perspective.

- 23 september 2009. Universiteit Antwerpen. Inaugural lecture of the Chair of Evidence

based Vaccinology.

Current topics in vaccinology: from basic ‘whom infects whom’ research to modelling

H1N1 flu.

Christel Faes

- 23 oktober 2009, Tervuren. VEE Studiedag Spatial risk factor analysis for Bluetongue

in Northern Europe.

- 23 oktober 2009. Tervuren. VEE Studiedag Risk approach models to estimate the

sensitivity for different surveillance components: bluetongue in belgium a case study.

- 22 oktober 2009. Second joint scientific meeting of the Methusalem consortium:

Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp and

Center for Statistics (Censtat), University of Hasselt. Universiteit Antwerpen.

European surveillance of antimicrobial consumption: outpatient antibiotic use in

Europe.

Tetyana Kadankova

- 1 oktober 2009. K.U.Leuven. Two –sided exit problems for several classes of

stochastic processes.

Qi Zhu

- 19-20 november 2009. IUAP Workshop on Modeling Association and Dependence in

Complex Data.

- 15-16 Oktober 2009. 17th Annual Meeting of the Belgian Statistical Society, Lommel. A

Bayesian approach to model the enzymatically 18O-labelled mass.

- Workshop on Data mining and bioinformatics for proteomics. Antwerpen. A Bayesian

approach to the quantification of overlapping peptides in Maldi-Tof mass spectra

(poster)

Adetayo Kassim

- 6-8 april 2009. 2nf IBS Channel Network Conference. Gent. Informative and

oninformative calls for gene expression in microarray experiments (poster)

= QM=

Suzy Van Sanden

- Janssen Pharmaceutica, Beerse. Biclustering procedures in a microarray setting.

- 17-19 november 2009. IWT Meeting Linz-Janssen. UHasselt, Nismes, Belgium

IWT: Biclustering

IWT: Pilot Studies

José Cortiñas

- 22 oktober 2009. Universiteit Hasselt.

Second joint scientific meeting Methusalem consortium: Vaccine and Infectious

Disease Institute (Vaxinfectio). Statistical tools to evaluate diagnostic tests in medical

microbiology.

- 15-18 september 2009. Leuven. Arenberg Doctoral School. Data Mining in practice.

Using tree-based methods and support vector machines to identify dengue

hemorrhagic fever cases base on symptoms and blood test results.

- 22 juni 2009. Universiteit Antwerpen.

ESAC Meeting with EU representants. Methods for identification and determinants.

- 11 maart 2009. Glaxo-Smith-Kline and Censtat Meeting.

Simplified modelling strategied for surrogate validation for multivariate failure-time

data.

- 24 april 2009. KIZOK and censtat Meeting. Bayesian methods and supervised learning

techniques.

Yovanna Castro

- 15-16 oktober 2009. 17th Annual Meeting of the Belgian Statistical Society. Lommel.

Survival analysis of interval censored data in injecting drug users.

Nele Goeyvaerts


Statistical inference on parovirus B19 immunology using data on social contacts and

serological status.

Arthur Gitome

- 6-8 april 2009. 2nd IBS Channel Network Conference. Gent. Estimating kinase activity

in calle lines and classification of based on the response to treatment using

PAMCHIPS.


Resampling based multiple testing in microarray experiments: permutations or

bootstrap ?

Dan Lin


Testing procedures on comparisons of several treatments with one control in a

microarray setting.

- 8 december 2009. Université de Liège. Ovrview of Biclustering Methods for high

dimensional “omic” data.

Tatsiana Khamiakova


Probe level filtering in microarray experiments.

- 17-19 november 2009. IWT Meeting, Linz-Janssen-Uhasselt, Nismes, Belgium.

QN=

Results of a simulation study on biclustering methods.

Cristina Sotto

- 17-20 november 2009. K.U.Leuven. IUAP. Workshop on Modeling Association and

Dependence in Complex Data. MCMC-based estimation methods for continuous

longitudinal data with non-random (non-)monotone missingness.

Saskia Litière

- 2 oktober 2009. VEE Studiedag @ CODA.

Estimating the herd-prevalence based on aggregate testing of animals.

- 23 oktober 2009. Tervuren, VEE Workshop. Risk-based surveillance.

Emanuele Del Fava

- 6-8 april 2009. 2nd IBS Channel Network Conference. Gent.

Estimating the prevalence and the force of infection of Parovirus B19 in Belgium using

Bayesian hierarchical mixture models.

- 15-16 oktober 2009. 17th Annual Meeting of the Belgium Statistical Society. Lommel.

The co-infection between HCV and HIV a joint modeling approach.

Birhanu Teshome Ayele


Pseudo-likelihood estimation for incomplete data.

Girma Minalu Ayele


Estimating the impact of school closure on social mixing behaviour and the

transmission of close contact infectious in eight European countries.

- 22 oktober 2009. Second joint scientific meeting of the Methusalem Consortium:

Vaccine and Infectious Disease Institute (Vaxinfectie), University of Antwerp and

Center for Statistics (Censtat),; University of Hasselt. Universiteit Antwerpen.

Applications of different statistical models to decide on the strategy for the diagnosis

of M. pneunomiae infections.

= QO=

Congressen (passieve deelname)

Noël Veraverbeke

- 16 februari 2009. K.U.Leuven. Inauguratie Belgische Franqui Leerstoel voor Tom

Snijders.

- 22 februari 2009. Universiteit Antwerpen. Inauguratie Franqui Leerstoel voor Geert

Molenberghs.

- 16-18 november 2009. Bijeenkomst Stochastici Lunteren, Nederland.


- 19-20 novermber 2009. IUAP-Workshop on Modeling Association and Dependence in

Complex Data. K.U.Leuven.

Roel Braekers

- 19-20 november 2009. IAP-Workshop on Modeling Association and Dependence in


Niel Hens

- 16-29 juni 2009. University of Washington, Seattle, USA. The first modelling infectious

disease course: SISMID

- 16, 17, 18, 23, 24 februari 2009. Leuven Short course on Statistical models for social

network data (Tom Snijders)

- 6-8 april 2009. Second IBS Channel Network Conference, Gent.

- 23-25 november 2009. NSDN+ Workshop on Statistics and the Life Sciences.

Groningen, Nederland.

Annouschka Laenen

- 6-8 april 2009. Second IBS Channel Network Conference. Gent.

Marc Aerts


Setia Pramana

- 1 oktober 2009. 11th Johnson & Johnson Pharmaceutical Conference of Statistics.

Beerse

- 22-26 juni 2009. 5th Hands-on course in advanced microarray data analysis.

Maastricht, Nederland.

- 19-20 november 2009. IUAP-Workshop on modeling Association and Dependence in

Complex Data. K.U.leuven.

Yovanna Castro

- 19-24 oktober 2009. Oberwolfach, Germany. Course on semiparametric and

nonparametric regression.

Ariel Alonso

- 6-8 april 2009. Second IBS Channel Network Conference. Gent.

- 16-19 juni 2009. 1st Summer Institute in Statistics and Modeling Infectious Diseases.

University of Washington, Seattle (with FWO Travel Grant) and University of

Washington (registration fee scholarship).

QP=

- 1-7 november 2009. Oberwolfach. Workshop: Design and anlysis of Infectious Disease

Studies, Mathematisches Forschungsinstitut Oberwolfach, Germany (with Oberwolfach

Leibniz Graduate Students travel grant)

Arthur Gitome

- 22-26 juni 2009. 5th Hands-on course in advanced microarray data analysis.

Maastricht, Nederland.

- 12, 13, 16 januari 2009. SAS course Macro. Hasselt.

Liesbeth Bruckers

- 10-14 mei 2009. 5th Conference of the Eastern Mediterannean Region of the

International Biometric Society, Istanbul, Turkije.



Thomas Neyens



Birhanu Teshome Ayele

- 22 oktober 2009. Second Joint Scientific Meeting. Methusalem Consortium: Vaccine

and Infectious Disease Institute (Vaxinfectio), UA and UH, Uantwerpen.

- 19-20 november 2009. K.U.Leuven. UAP Workshop on Modeling Association and

Dependence in Complex Data.

Christel Faes

- Januari 2009. UHasselt. SASD Course (Franky de Cooman)

- 16-18 juni 2009. Southampton, UK. Hierarchical Spatial data (4 day course, Alan

Gelfand)

- 1 augustus 2009. Joint Statistical Meeting, Washington, USA. Missing Data in

Longitudinal Studies (M. Daniels and J. Hogan)

- 2 oktober 2009. Vose Consulting, Gent. Workshop Risk-based animal disease

surveillance (Koen Mintiens).

Aklilu Habteab Ghebretinsae

- 19-20 no vember 2009. IUAP Workshop on Modeling Association and Dependence in


Paul Janssen



Complex data. K.U.Leuven.

Ivy Jansen

- 10-14 mei 2009. 5th Conference of the Mediterranean Region of the International

Biometric Society, Istanbul, Turkije.

Onderzoeksgroep: STATISTIEK 2009 A Identiteit van de ...- Reliability estimation in clinical trial...

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