Medical Statistics (basis)

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simple statistics

description

Simple Medical Statistics (basis)

Transcript of Medical Statistics (basis)

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simple statistics

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simple statisticssensitiviteit

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sensitiviteit = hoe vaak is de test positief als de ziekte er is

sensitiviteit = 18/(18+4) =82%

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simple statisticsspecificiteit

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specificiteit =hoe vaak is de test negatief als de ziekte er niet is

specificiteit = 23/(23+4) =85%

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simple statisticsPos. voorspellende waarde

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PPV =als de test positief is, hoe groot is dan de kans dat de zieket er is

PPV = 18/(18+4) =82%

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simple statisticsNeg. voorspellende waarde

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NPV =als de test negatief is, hoe groot is dan de kans dat de ziekte er niet is

NPV = 23/(23+4) =85%

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simple statisticsLikelihoof ratio

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LR = als de test positief is, hoeveel groter is de kans dan dat patient ziek is tov niet

LR =sensitiviteit/(100%-specificiteit)

Dus hier: 82%/(100-85%) = 5.5

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simple statisticsStandaard deviatie

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simple statisticsbetrouwbaarheidsinterval

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simple statisticsP-waarden

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P-waarden

P value: the probability of any observed difference having

happened by chance

p = 0.05 = significantp = 0.01 = sterk significantp = 0.001 = zeer sterk significant

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P-waarden

Valkuilen:- te kleine studie- te grote studie- ook klinisch significant?

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Risk / Odds Ratio1000 voetballers en 1000 niet-voetballers: # eerste 12, tweede 4

Risk?Risk ratio?Odds ratio?

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Risk / Odds RatioRisk voetballers 12/125 = 0.096, anderen 4/134 = 0.030Risk ratio: 0.096 gedeeld door 0.030 = 3,2Odds # voetballers: 12/113 =0.11, bij anderen 4/130 =0.031Odds ratio: 0.11/0.031 = 3.55

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Correlatie

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http://sumed.sun.ac.za/Portals/0/Repository/Medical-Statistics-Made-Easy.3f8ceb88-f35b-4f29-8d70-17e78ce071d8.pdf