AUTHOR INDEX

March 1, 1993

Ames, M. M., 1032Atnox, D., 1098Angstwurm, M., 1027

Baird, S., 1122Balis, F. M., 1032Baserga, R., 1102Basrur, V. S., 1091Baudoin, C, 1175Beamer, W. G., 1059Belardelli, F., 1107Bernerd, F., 1175ninnami. M., 1149Blaney, S. M., 1032Braun, S., 1027Braunschweiger, P. G., 1091Brigati, D. J., 937Brockmöller,J., 1004Bruno, R., 1037Bucana, C. D., 937Buchhagen, D. L., 1098Budding, M., 977

Calcagnile, A., 1149Cameron, M. J., 1043Carmichael, P. L., 944Carson, D. A., 1098Cavenee, W. K., 957Chamberlin, H., 1142Chang, A. E., 1043Chang, H. R., 1122Chang, K-T., 1079Chang, S., 1122Chen, T-M., 1167Chiù,M. L., 977Christou, M., 968Clavel, M., 1037Cleary, K. R., 937Clemente, F., 1182Cole, D. E., 1032Couderc, B., 1182Craig, C., 1032Croop, J. M., 977

Day, N. K., 1188Defendi, V., 1167de Jong, S., 1064Démarchez,M., 1175de Tribolet, N., 957de Vries, E. G. E., 1064DiMassimo, B. I., 1195Dogliotti, E., 1149Drakoulis, N., 1004Dumenco, L. L., 997

Ellis, L. M., 937Emi, M., 1172Engelman, R. W., 1188Estival, A., 1182Extra, J-M., 1037

Ferrantini, M., 1107Fidler, I. J., 937Fortini, P., 1149Frey, C. M., 1079Fu, X., 1204Fujii. T., 1136

Fujiki, H., 992, 1012Fujimoto, K., 1136Fujita, H., 1156Fujiwara, Y., 1172Furukawa, T., 1204

Gabriele, L., 1107Gazdar, A. F., 1079Gerson, S. L., 997Gerwin, B. L, 985Cornelia, L., 1102Good, R. A., 1188Gresser, I., 1107Grover, P. L., 944

Hammond, D., 1032Harel, W., 1113Harris, C. C., 985Hart, I. R., 962Hattori, Y., 1136Henttu, P., 1051Hermann, G. G., 1162Hoffman, R. M., 1204Hollande, E., 1182Hoon, D. S. B., 949Hori, M., 953Hörn,T., 1162Houdek, P. V., 1091Hsiao, S-H., 1079

Izbicki, J. R., 1027

Jameson, B. A., 1102Jefcoate, C. R., 968Jones. P. A., 1162Jothy, S., 957

Kaido, T., 1107Kaneda, Y., 949Karg, O., 1027Kato, Y., 953, 1172Katoh, O., 1136Ke, Y., 985Keith, I. M., 968Kerb, R., 1004Kikuchi, T., 957Kitagawa, T., 953Kitajima, M., 1204Koda, K., 1122Kohno, K., 1085Kolachana, P., 1023Komatsu, N., 1156Komori, A., 992Kooistra, A. J., 1064Krailo, M.. 1032Kramer, B. S., 1079Kramer, R. A., 977Kronauge, J. F., 977Kubota, T., 1204Kuwano, M., 1085Kwon, H., 1017

Le Bail, N., 1037Lechner, J. F., 985Lecoq, S., 944Leduy, L., 957Louvel, D., 1182

Lysik, R. M., 1195Lyubsky, S., 1195

Markoe, A. M., 1091Marty, M., 1037Matsuo, K-i., 1085McKenna, W. G., 1128Meneguzzi, G., 1175Meyer, F., 1107Meyer, K. B., 1023Minnick, D. T., 997Mitchell, M. S., 1113Mori, T., 1172Morisaki, T., 949Morton, D. L., 949Mulder, N. H., 1064Mulholland, G., 1102Mulligan, L., 957Muschel, R. J., 1128

Nakajima, T., 1172Nakamura, Y., 1172Nichols, P. W., 1162Nitz, M., 1004Nobori, T., 1098

Oesch, F., 944Ohashi, K., 953Ohata, H., 1172Ohneseit, P. F., 1162Ohnuki, Y., 985Ohta, T., 992Ohtake, K., 953Okabe, S., 1012Olopade, O. L, 1098Olumi, A. F., 1162Ortonne, J. P., 1175

Pantel, K., 1027Papadopoulou, L. C., 1072Parker, B., 1098Passlick, B., 1027Pecoraro, G., 1167Peretti, M., 1107Perng, R-P., 1079Phillips, D. H., 944Pietrzkowski, Z., 1102Pisani, A., 1175Piwnica-Worms, D., 977Platt, K. L., 944Plavec, !.. 1107Poplack, D. G., 1032Portier, M. M., 1175Prats, H., 1182Proietti, E., 1107

Radinsky, R., 937Ravichander, P., 1142Reaman, G., 1032Reddel, R. R., 985Reid, J. M., 1032Rempel, S. A., 957Rideout, W. M., III, 1162Riethmüller,G., 1027Roots,!., 1004Ross, R. K., 1162Rousseau, F., 1037

Rutz, H-P., 957

Sakai, K., 1043Sakamoto, H., 1136Salghetti, S. E., 985Sanchez, R., 937Santodonato, L., 1107Santos, O., 1091Sasaki, H., 1136Sato, S., 1085Schroeder, M. E., 968Schwade, J. G., 1091Schwanz, E. L., 1142Sedwick, W. D., 997Shé,M. N., 944Shen, X., 968Shu, S., 1043Shultz, K. L., 1059Smith, M. T., 1023Sondak, V. K., 1043Spruck, C. H., III, 1162Staib, L., 1113Steven, K., 1162Subrahmanyam, V. V., 1023Sugano, H., 953Suganuma, M., 992, 1012Sugimura, T., 1136Surh, Y-J., 1017Szinai, I., 1098

Tanimura, H., 1085Tannenbaum, S. R., 1017Tennent, B. J., 1059Terada, M., 1136Thetter, O., 1027Tsai, C-M., 1079Tsai, Y. C, 1162Tsiftsoglou, A. S., 1072

Uchiumi, T., 1085Uchiyama, A., 949

Van Meir, E. G., 957van Zeeland, A. A., 1149Vaysse, N., 1182Veigl, M. L., 997Vihko, P., 1051Vile, R. G., 962Vrieling, H., 1149

Watanabe, M., 1204Wernicke, D., 1102Whitbread, J. A., 1142Willey, J. C., 985

Yamada, Y., 1085Yanagisawa, A., 953Yang, A. S., 1162Yatsunami, J., 992, 1012Yoshizawa, H., 1043Yoshizawa, S., 1012Yu, M. C, 1162Yuspa, S. H., 992Yuzuki, D. H., 949

Zhang, H. B., 1128Zhang, L., 1023Zijlstra, J. G., 1064Zucker, S., 1195

1212

AMERICAN ASSOCIATION FOR CANCER RESEARCH

GUIDELINES FOR APPLICATION FOR ACTIVE ANDCORRESPONDING MEMBERSHIP

BENEFITS OF MEMBERSHIP

The American Association for Cancer Research (AACR) is ascientific society consisting of laboratory and clinical cancerresearchers. It was founded in 1907 "to bring together active

investigators of the cancer problem for presentation and discussion of new or significant observations; and to foster research incancer and other phenomena of growth." Members of the AACR

enjoy the following benefits:

1. subscriptions to the journals Cancer Research, CellGrowth & Differentiation, and Cancer Epidemiology, Bio-markers & Prevention at the reduced member rate;

2. the privilege of sponsoring an abstract for presentation atthe AACR annual meeting;

3. an advance copy of the Program and Proceedings pertaining to each annual meeting;

4. a reduced registration rate at all scientific meetings;5. early notification of events in the AACR's series of special

conferences;6. subscriptions to any future AACR journals at reduced

member rates;7. reduced rates for the AACR Employment Register;8. the benefit of AACR's public education activities;

9. the receipt of AACR newsletters, meeting announcements,and an up-to-date membership directory.

QUALIFICATIONS FOR MEMBERSHIP

Active membership in the AACR is open to investigators wholive in the Americas, and who have conducted two years ofmeritorious research that has resulted in publications relevant tocancer. If a candidate is working in a research area not directlyrelated to the cancer field but has conducted research of exceptional scientific merit, he or she may also qualify for membership.

Corresponding membership is open to qualified persons whoare not residents of the Americas. The requirements for corresponding membership are the same as those for active membership. Visiting scientists from outside the Americas who intendto return to their countries of origin soon after submitting theirapplications should apply for corresponding membership. Allother individuals should apply for active membership and transferto corresponding status at a later date if they should leave theAmericas.

PROCEDURES FOR APPLICATION

There are three deadlines for receipt of a membership application: March 1, July 1, and October 1 of each year. TheMembership Committee will review all complete applications foractive membership that have been received by these deadlinesand will submit recommendations on each candidate to the Boardof Directors which formally elects all members. The same procedure is followed by the Special Memberships Committee whichreceives applications for corresponding membership. Candidateswill be notified according to the following schedule:

Receipt of Applicationin AACR Office Notification of Candidate

March 1 MayJuly 1 SeptemberOctober 1 December

A complete application consists of the following material:

1. 6 copies of the form on the opposite side of this page,with all requested information provided.

2. 5 copies of the candidate's most current curriculum vitae

and bibliography.3. 5 copies of a letter of recommendation from a nominator

who is an active, emeritus, or honorary member of theAACR (at least one copy must be a signed, original letter).This letter should describe the candidate's achievements

in laboratory research, clinical investigations, or epidemi-ological research, and it should affirm that this researchadheres to accepted ethical standards.—OR—The nominator may supply the responses requested at the bottomof the application form in the section entitled "STATEMENT OF SUPPORT" (at least one copy of the form must

be the signed original).4. 5 copies of a letter of recommendation as described in

Item 3 above from a seconder who is an active, emeritus,or honorary member of the AACR (at least one copy mustbe a signed, original letter).—OR—The seconder maysupply the responses requested at the bottom of theapplication form in the section entitled "STATEMENT OFSUPPORT" (at least one copy of the form must be the

signed original).5. 5 reprints of each of two publications on which the candi

date appears as author.All material should be collated into five complete sets with the

original application form as a covering document and sent to theaddress given below. Questions regarding procedures for membership application may also be directed to the following address:

American Association for Cancer ResearchPublic Ledger Building

620 Chestnut St.Suite 816

Philadelphia, PA 19106-3483215/440-9300

RESPONSIBILITIES OF MEMBERSHIP

Candidates should be aware of the following responsibilitiesof membership in the AACR. Active members must pay annualdues, a major portion of which is designated for a subscriptionto at least one of the AACR's publications. Newly elected mem

bers of the AACR who have already purchased subscriptions toCancer Research, Cell Growth & Differentiation, or Cancer Epidemiology, Biomarkers & Prevention at the higher, nonmemberrate will receive reimbursement of the unused portion of thosesubscriptions once their first year's membership dues are paid

in full.All corresponding members elected after May 23, 1985, are

required to pay an annual assessment in lieu of dues. Thisassessment, which is equivalent to that portion of the regulardues that pertains to support of activities other than publications,is imposed to defray the cost of sending AACR publications tomembers outside the Americas. Corresponding members may,if they wish, subscribe to Cancer Research, Cell Growth &Differentiation, or Cancer Epidemiology, Biomarkers & Preventionat the reduced member rate.

Applicants elected in May will be responsible for payment ofthat year's dues; applicants elected in September and December

will pay dues in the following year. Applicants elected in May andSeptember will be eligible to sponsor an abstract for the nextannual meeting. Every effort will be made to afford the sameopportunity to applicants elected in December.

Margaret FotiExecutive Director

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •¿�620 Chestnut St. •¿�Suite 816 •¿�Philadelphia, PA 19106-3483

APPLICATION FOR MEMBERSHIP

CATEGORY OF MEMBERSHIP:

NAME OF CANDIDATE:

D Active D Corresponding

DATE OF BIRTH:LAST FIRST M.I.

PRESENT POSITION/TITLE: _INSTITUTIONAL AFFILIATION:.INSTITUTIONAL ADDRESS:

(City)TELEPHONE NUMBER:FAX NUMBER:

(State/Province) (Country) (Postal Code)

PRIMARY FIELD OF RESEARCH (Please check only one):Biochemistry and Biophysics BiostatisticsCellular Biology and Genetics Clinical InvestigationsEpidemiology ImmunologyPreclinical Pharmacology and Experimental TherapeuticsVirology Other:

. Carcinogenesis

. EndocrinologyMolecular Biology and Genetics

(Please specify)

ACADEMIC DEGREES (Including where and when granted)

EXPERIENCE SINCE HIGHEST DEGREE WAS GRANTED (Please list most recent first)

PUBLICATIONS (Reprints of two articles on which the candidate appears as an author must accompany this application. For thesetwo articles list the authors, title, journal, volume, inclusive pages, and year. Do not submit abstracts.)

CANDIDATE NOMINATED BY:(Please type or print)

CANDIDATE SECONDED BY:(Please type or print)

STATEMENT OF SUPPORT (in place of letters of recommendation)Instead of submitting letters of recommendation, either the nominator or the seconder or both may complete the following section:

How long has the candidate worked in the field of cancerresearch? yearsWill the candidate make a long-term contribution to cancerresearch? Yes NoDoes the candidate's research adhere to accepted ethical stand

ards? Yes No

I therefore recommend this candidate for membership in theAmerican Association for Cancer Research.

How long has the candidate worked in the field of cancerresearch? yearsWill the candidate make a long-term contribution to cancerresearch? Yes NoDoes the candidate's research adhere to accepted ethical stand

ards? Yes No

I therefore recommend this candidate for membership in theAmerican Association for Cancer Research.

Signature of nominator* Date Signature of seconder*

See Guidelines for Application on the reverse side of this form for further instructions.

* Both nominator and seconder must be active, emeritus, or honorary members of the AACR.

(This form may be reproduced.)

Date

AMERICAN ASSOCIATION FOR CANCER RESEARCH

GUIDELINES FOR APPLICATION FOR ASSOCIATE MEMBERSHIP

QUALIFICATIONS FOR MEMBERSHIP

Associate membership is open to graduate students, medicalstudents, postdoctoral fellows, and physicians in training wholive in the Americas and who are following a course of study orwho are working in a research program relevant to cancer.

BENEFITS OF MEMBERSHIP

The American Association for Cancer Research (AACR), ascientific society consisting of laboratory and clinical cancerresearchers, was founded in 1907 "to bring together active

investigators of the cancer problem for presentation and discussion of new or significant observations; and to foster research incancer and other phenomena of growth." Associate members of

the AACR enjoy the following benefits:

1. the privilege of sponsoring an abstract for presentation atthe AACR annual meeting provided that (a) the associatemember is the presenter of the abstract and (b) an activemember in good standing of the AACR also signs theabstract in support of the work (In this instance, the activemember who cosigns the abstract does not lose his or herown sponsorship privilege.);

2. an advance copy of the Program and (if one has beenpurchased by the associate member) the Proceedings ofthe American Association for Cancer Research which contains abstracts of all papers being presented at each annualmeeting;

3. the privilege of registering for the annual meeting at thelow student rate (This rate is otherwise available only topredoctoral students.);

4. preferred access to the AACR Employment Register;5. optional subscriptions to the journals Cancer Research,

Cell Growth & Differentiation, and Cancer Epidemiology,Biomarkers & Prevention at the reduced member rate;

6. subscriptions to any future AACR journals at reducedmember rates;

7. early notification of events in the AACR's new series of

small scientific meetings on timely scientific topics;8. the receipt of AACR newsletters, meeting announcements,

and an up-to-date membership directory; and9. the facilitation of informal scientific exchange with leading

researchers in the cancer field.

PROCEDURES FOR APPLICATION

Persons wishing to apply for associate membership must usethe official application form on the reverse side of these instructions. Each candidate for associate membership must be nominated by an active member in good standing of the AACR. Threecompleted copies of the form should be submitted; at least oneof these copies must carry the original signatures of both thecandidate and the active member nominator. The applicationform may be submitted to the Association Office at any time.

After review of applications for associate membership, the Executive Director will notify candidates of their election or deferralwithin one month of the receipt of the application form. A checkin the amount of $30, which represents one year's dues payment,

must accompany the application. This fee will be refunded toany candidate deemed to be ineligible for associate membership.Checks should be in U.S. currency, made payable to AACR, Inc.,and drawn on a U.S. bank. Send the three copies of the application form and the $30 dues payment to:

American Association for Cancer ResearchPublic Ledger Building

620 Chestnut St.Suite 816

Philadelphia, PA 19106-3483215/440-9300

RESPONSIBILITIES OF MEMBERSHIP

Associate members must pay annual dues in an amount to bedetermined by the AACR Board of Directors. Dues for 1993 havebeen set at $30 per year. If an application is submitted by August31, the accompanying dues payment will be credited to thecurrent year. Candidates submitting applications between September 1 and December 31 may indicate whether they wish theirdues payments credited to the current or forthcoming year.Candidates should be aware, however, that associate membersmay sponsor an abstract for the annual meeting only if their duesfor the current year are paid. For example, an associate membersubmitting an abstract in December 1993 for the forthcomingannual meeting must have paid dues for 1993. Any newly electedassociate members of the AACR who have already purchasedsubscriptions to Cancer Research, Cell Growth & Differentiation,or Cancer Epidemiology, Biomarkers & Prevention at the higher,nonmember rate will receive a refund for the unused portion ofthat subscription upon receipt of their payment for a member's

subscription.Each Fall the AACR will send to current associate members

an invoice for dues for the forthcoming year. Payment of thisinvoice must be accompanied by a statement signed by theassociate member's current registrar, dean, or department head,verifying the member's current academic status. The Association's By-Laws state that dues are payable for each year in

advance on or before January 1 of the year to which they shouldbe applied. An individual may be an associate member for amaximum of five years. Each year in which an individual paysdues will count as one full year of associate membership. Thus,an associate member who pays dues for 1993 may retainassociate membership until December 31, 1997. The Board ofDirectors may terminate the membership of an associate memberwhose dues are in arrears for two years.

Margaret Foti,Executive Director

AMERICAN ASSOCIATION FOR CANCER RESEARCHEIGHTY-FOURTH ANNUAL MEETING

May 19-22, 1993

Orange County Convention CenterOrlando, Florida

ADVANCE REGISTRATION FORM(Please print or type)

NAME:Last Name First Name/Middle Initial AACR Member Number

TITLE: ADDRESS:Institution

Street, Building, or Post Office Box

City

TELEPHONE:

State or Province Zip/Postal Code

FAX:

Country (if not U.S.I

I ICheck this box if you have a physical disability and special requirements for transportation, hotel accommodations, or other facilitiesconnected with the meeting. A member of the Association Staff will contact you.

WHAT IS YOUR PRIMARY FIELD OF RESEARCH (Please check only one):LJ'Biochemistry and Biophysics LJ 2Biostatistics LJ'Carcinogenesis LJ'Cellular Biology & Genetics LU5Clinical InvestigationsLJ "Endocrinology LU'Epidemiology LJ "Immunology LJ "Molecular BiologyLJ '"Preclinical Pharmacology & Experimental Therapeutics LJ "Virology LJ '2Other (please specify):

ARE YOU THE PRESENTER OF AN ABSTRACT SUBMITTED FOR THE 1993 AACR MEETING? D Yes D No

ON WHICH DAYS WILL YOU ATTEND THE 1993 AACR ANNUAL MEETING?D Wednesday, May 19 LJ Thursday, May 20 UFriday, May 21 D Saturday, May 22

WILL YOU ATTEND THE ASCO MEETING IN ORLANDO? D Yes D No

ON WHICH DAYS WILL YOU ATTEND THE 1993 ASCO ANNUAL MEETING?D Sunday, May 16 D Monday, May 17 D Tuesday, May 18

PAYMENT OF REGISTRATIONFees may be paid by check or with a MasterCard, VISA, American Express, or Eurocard account. All payments must be made in U.S.currency, and all checks must be drawn on a U.S. bank. Payment must accompany this form; purchase orders will not be accepted aspayment. Honorary and emeritus members may register gratis.

FEES On or BeforeMar. 29

$ 90$ 0$185

LJ Active/Corresponding Member RateLJ Honorary/Emeritus Member RateLJ Nonmember Rate

(includes a copy of AACR Proceedings)LJ Associate Member/Student Rate* $ 45

(does not include a copy of AACR Proceedings)LJ AACR Proceedings' $ 35

LJ Overseas Airmail Surcharge $ 22

After METHOD OF PAYMENTMar. 29 LJ Check payable to AACR, Inc. in U.S. currency, drawn on a

$115 U.S. bank$ 0$210

$ 55

$ 35N/A

Total Enclosed or Charged

Person/Institution Issuing Check Check No.

LJ MasterCard LJ VISA LJ American Express G Eurocard

Account Number and Expiration Dutc

Signature

THE DEADLINE FOR REDUCED REGISTRATION FEES IS MARCH 29, 1993. Registration by mail willbe accepted until April 16. Registration will also be possible at the Orange County Convention Center from May 18-22.'"Students must enclose a statement, signed by the registrar, dean, or department head of their university or college on official letterhead, confirming their

status. Postdoctoral fellows or physicians in training do not qualify for the student registration rate unless they are associate members of theAACR. An application for associate membership may accompany this form, but these should be submitted well before the March 29 deadline as review ofthe associate membership application may delay registration.+AACR members with paid-up subscriptions to an AACR journal and registrants who pay the nonmembcr fee receive the Proceedings automatically. Ifthese members or nonmembers check this box and pay the $35 fee, they will receive an additional copy of the Proceeding«.

Optional payment for registrants outside of the U.S. and Canada only. Registrants paying this surcharge will receive meeting publications via air mail-printed matter before the annual meeting.

Mail all advance registration forms with applicable fees to Annual Meeting Registration. American Association for Cancer Research, Inc., Public LedgerBuilding, 620 Chestnut Street, Suite 816, Philadelphia. PA 19106-3483. FAX: 215-440-9313. Badges and receipts will be sent to you in April or early May.AACR members in good standing will receive copies of the Program and Proceedings prior to the meeting. Nonmember and student registrants who meetthe March 29 deadline will also receive the Program and (if they have purchased it) the Proceedings prior to the meeting. Nonmembers and students whodo not meet the deadline must pick up publications at the meeting site.

REFUND POLICYRefunds on registration fees will be granted on written request received in the AACR Office by May 12, 1993. Requests received after this date will not behonored. Receipts and badges (if they have been mailed) must be returned to the AACR Office with the refund request. A cancellation fee of $25 will bededucted from all refunds to cover administrative costs.

(This form may be reproduced.'

AMERICAN ASSOCIATION FOR CANCER RESEARCH, INC.Public Ledger Building •¿�620 Chestnut St. •¿�Suite 816 •¿�Philadelphia, PA 19106-3483

APPLICATION FOR ASSOCIATE MEMBERSHIP

NAME OF CANDIDATE: DATE OF BIRTH:.LAST FIRST M.I.

INSTITUTIONAL AFFILIATION:.INSTITUTIONAL ADDRESS: _

(City)TELEPHONE NUMBER:.FAX NUMBER:

(State/Province) (Postal Code) (Country)

PRESENT ACADEMIC STATUS/TITLE (Please check only one):Graduate Student Medical StudentPhysician in Training Postdoctoral Fellow

PRIMARY FIELD OF RESEARCH (Please check only one):Biochemistry and Biophysics Biostatistics

Cellular Biology and Genetics Clinical InvestigationsEpidemiology ImmunologyPreclinical Pharmacology and Experimental TherapeuticsVirology Other:

. Carcinogenesis

. Endocrinology

. Molecular Biology and Genetics

(Please specify)

ACADEMIC DEGREES (Please indicate degree(s) acquired to date along with the name of the academic institution and date ofreceipt. Provide information on degree currently being sought and the anticipated date of completion of this degree program.)

RELEVANT RESEARCH EXPERIENCE NOT RELATED TO COURSE WORK (Please list most recent first.)

PUBLICATIONS (List the authors, title, journal, volume, inclusive pages, and year of any article in a peer-reviewed journal on whichthe candidate appears as an author. Do not list abstracts. Continue on a separate sheet, if necessary.)

CANDIDATE NOMINATED BY:(Please type or print name of AACR active member in good standing.)

SIGNATURESI hereby apply for associate membership in the American Association for Cancer Research. I have read the instructions on thereverse side of this form, and I understand the privileges and responsibilities of this class of membership. I certify that the statementson this application are true.

Signature of Candidate: Date:

I recommend this candidate for associate membership in the American Association for Cancer Research. To the best of myknowledge, the candidate is qualified for this class of membership, and the statements on this application are true.Signature of Nominator*: Date:

Submit three copies of this form. At least one copy must contain the original signatures of the candidate and the nominator. Enclosea check for $30 in U.S. funds made payable to AACR, Inc. and drawn on a U.S. bank. Check one of the following boxes only if thisform is being submitted between September 1 and December 31 :

The enclosed dues payment should be applied to the

D current D forthcoming calendar year.

(NOTE: If dues are applied to the forthcoming year, membership will take effect on January 1, but the candidate will not be eligibleto sponsor an abstract for presentation at the annual meeting in May of that year.) See Guidelines for Application on the reverseside of this form for further instructions.

' Nominator must be active, emeritus, or honorary member of the AACR.

(This form may be reproduced.)

THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNOUNCESAN AACR SPECIAL CONFERENCE IN CANCER RESEARCH

GeneticControlofCellGrowthApril 13-17,1993

San Luis Hotel,Galveston,Texas

LAUREATESCONFERENCEGeneralMotorsCancerResearchFoundation

CONFERENCECHAIRPERSONS

LelandH.Hartwell/ Seattle,WAPeterK.Vogt/ LosAngeles,CA

GeorgeF.VandeWoude/ Frederick,MD

SCIENTIFICPROGRAM

TranscriptionStevenL.McKnight/ S.SanFrancisco,CAKevinStruhl/ Boston,MATomCurran/ Nutley,NJRobertG.Roeder/ NewYork,NY

SignalsStuartKauffman/ SantaFe,NMJosephR.Nevins/ Durham,NCAnthonyP.Mahowald/ Chicago,ILRobinE.Oenell/ Manhattan.KS

CellCycleJamesM.Roberts/ Seattle,WAAndrewMurray/ SanFrancisco,CAJoanV. Ruderman/ Boston,MAStevenI. Reed/ LaJolla,CA

InstabilityTheaD.Tlsty/ ChapelHill,NCBrianJ. Reid/ Seattle,WAMichaelB.Kastan/ Baltimore,MDJohnH.Wilson/ Houston,TX

DevelopmentAndyGolden/ Pasadena,CAEricN.Olson/ Houston,TXLuisParada/ Frederick,MDSarahCrittenden/ Madison,Wl

OncogenesEdwardE.Harlow/ Charlestown,MAF.MichaelHoffmann/ Madison,WlHaroldE.Varmus/ SanFrancisco,CAStephenH.Friend/ Charlestown,MA

TransgenicsStanleyJ. Korsmeyer/ St.Louis,MOWenHwaLee/ SanAntonio,TXDouglasHanahan/ SanFrancisco,CAAllanBradley/ Houston,TX

InformationandApplicationForms

American Association for Cancer ResearchPublic Ledger Building620 Chestnut Street, Suite 816Philadelphia, PA 19106-3483215-440-9300 215-440-9313 (FAX)

Guidelines for Submitting Disksto

American Association for Cancer Research Publications

The word processing packages that we prefer are as follows:

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Microsoft Word Macintosh(Versions 1-4) 400/800K

Wang OIS (WPS)

Also acceptable:

Apple II DOS 3.3Apple with Appleworks SoftwareApple III Plus DOS 3.3Apple Macintosh 400K Disc/

MacWrite 2.2 (text)Apple Macintosh Plus 800K Disc/

MacWrite 4.5 (text)CPT 8000DEC WPS-8

DEC Decmate IIDEC Decmate IIIDisplay Write 3

Display Write 4IBM Display writer Word Processor 6580Lanier Business One StepLanier No ProblemLanier Super No ProblemMASS-11 PC

MultimatePC WritePFS Professional WriteVolkswriter 4.0

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To expedite work and for your own security, we do require that you submit a hard copy printout of the diskfile. The tables and equations will be keyed from this hard copy. We also need to know the name of the file tobe converted, the type of hardware (e.g., IBM PC) on which the files were created, the operating system (e.g.,DOS 3.3), and the version of the software (e.g., WordPerfect 5.1) used to create the file.

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Nt»«•A-,'^T^. S.

\

\83rd ANNUAL MEETING OF THE

AMERICAN ASSOCIATION FOR CANCER RESEARCHMAY 20-23,1992 •¿�SAN DIEGO

Eac/7cassette is $11.50. •¿�Programs consist of one to three cassettes.

D CAN 201 Sixteenth Richard and Hinda Rosenthal$11.50 Foundation Award Lecture: How Cancer«

Evade Chemotherapy[Michael M. Gottesman] and General MotorsCancer Research Foundation JournalismAwards (One cassette)

D CAN 202 JOINT AACR/ASCO PLENARY SESSION:$23.00 Chemoprevention of Cancer

(Two cassettes)D CAN 203 Minisymposium Immunology 1 : Vaccine

$23.00 and Related Therapies (Two cassettes)D CAN 204 Minisymposium Precllnical

$23.00 Pharmacology/ExperimentalTherapeutics 1: New Methods forPredicting Drug Efficacy (Two cassettes)

D CAN 205 Minisymposium Carcinogenesls 1:$23.00 Perturbations of Cell Cycle Control and

Apoptosis (Two cassettes)D CAN 206 Minisymposium Biochemistry 1: Cellular

$23.00 Responses to Genomic Insult(Two cassettes)

D CAN 207 Presentation by the Director of The$11.50 National Cancer Institute (One cassette)

D CAN 208 Plenary Session 2: Novel Approaches to$23.00 Tumor Immunology (Two cassettes)

n CAN 209 Symposium 1: Hereditary Predisposition$23.00 to Cancer (Two cassettes)

D CAN 210 Symposium 2: Antitumor Activities of$23.00 Cytokines (Two cassettes)

D CAN 211 Minisymposium Biology 3:$34.00 Metalloproteinases (Three cassettes)

D CAN 212 Minisymposium Preclinical$34.00 Pharmacology/Experimental Therapeutics 4:

Protein Kinases: A Target for Therapy(Three cassettes)

n CAN 213 Minisymposium Clinical Investigations 3:$34.00 Molecular Markers of Risk and Prognosis

(Three cassettes)D CAN 214 Minisymposium Molecular Biology/

$34.00 Virology 3: Oncogenes (Three cassettes)D CAN 215 Eleventh Bruce F. Cain Memorial Award

$11.50 Lecture: Taxol: Mechanisms of Action andResistance [Susan Band Horwitz](One cassette)

D CAN 216 Minority Issues Committee Symposium:$23.00 Careers and OpportunitésIn Cancer

Research: Success and Survival in the1990» (Two cassettes)

D CAN 217 Meet the Expert Sunrise Session:$11.50 Contemporary Cytogenetics (One cassette)

D CAN 218 Meet the Expert Sunrise Session: Gene$11.50 Therapy (One cassette)

D CAN 219 Symposium 3: Molecular Genetics of Cancer$34.50 (Three cassettes)

D CAN 220 Plenary Session 3: The Role of Cell$23.00 Adhesion in Invasion and Metastasis

(Two cassettes)D CAN 221 Symposium 4: Multiple Genetic Alterations

$23.00 and Multiple Steps in Carcinogenesis(Two cassettes)

D CAN 222 Minisymposium Immunology 4: Tumor$34.50 Infiltrating Lymphocytes (Three cassettes)

D CAN 223 Minisymposium Carcinogenesis 7:$34.50 Molecular Alterations In Oncogenes and

Tumor Suppressor Genes (Three cassettes)D CAN 224 Minisymposium Preclinical Pharmacology/

$34.50 Experimental Therapeutics 10: Reversal ofDrug Resistance III (Three cassettes)

O CAN 225 Minisymposium Clinical Investigations 7:$34.50 Biologicals for Treatment (Three cassettes)

D CAN 226 Thirty-Second G.H.A. Clowes Memorial$11.50 Award Lecture: Drug Resistance:

Genotype versus Phenotype [June L. Biedler](One cassette)

D CAN 233$23.00

D CAN 227 Symposium 5: Genomic Fluidity$23.00 (Two cassettes)

D CAN 228 Symposium 6: Programmed Cell Death$23.00 (Apoptosis) in the Etiology and Therapy of

Cancer (Two cassettes)D CAN 229 Symposium 7: Receptor Signaling and

$23.00 Transduction (Two cassettes)D CAN 230 Minisymposium Epidemiology and

$23.00 Prevention 2: Epidemiology and Prevention(Two cassettes)

D CAN 231 Minisymposium Clinical Investigations 10:$23.00 Novel Therapies (Two cassettes)

n CAN 232 Minisymposium Carcinogenesis 11 :$23.00 Cellular and Molecular Changes In

Carcinogenesis (Two cassettes)Minisymposium PreclinicalPharmacology/Experimental Therapeutics16: New Mechanisms of Multidrug Resistance(Two cassettes)

D CAN 234 Presidential Address: Transforming Growth$1 1.50 Factors and Cancer: New Insights

[Harold L. Moses] (One cassette)D CAN 235 Annual Business Meeting

$1 1.50 (One cassette)D CAN 236 Meet the Expert Sunrise Session:

$1 1.50 Proteoglycans and Cell Adhesion (One cassette)D CAN 237 Meet the Expert Sunrise Session: A New

$1 1.50 Therapeutic Approach for Cancer Treatment:Sequence-specific Antisense Nucleic AcidAnalogs (One cassette)

D CAN 238 Plenary Session 4: Cell Cycle Control$23.00 (Two cassettes)

D CAN 239 Symposium 8: HIV-associated Malignancies$23.00 (Two cassettes)

D CAN 240 Symposium 9: Antlcancer Drug Design and$23.00 Discovery (Two cassettes)

D CAN 241 Minisymposium Endocrinology 5:$23.00 Endocrine, Autocrine, and Paracrlne

Growth Factors (Two cassettes)D CAN 242 Minisymposium Biochemistry 5: Oncogenes

$23.00 (Two cassettes)D CAN 243 Minisymposium Carcinogenesis 15: Genetics

$23.00 of Cancer Susceptibility (Two cassettes)D CAN 244 Minisymposium Preclinical Pharmacology /

$23.00 Experimental Therapeutics 22: AntineoplasticProperties of Ether Llpids (Two cassettes)

D CAN 245 First American Cancer Society Award$1 1.50 Lecture: Human Gastric Carcinogenesis: A

Multistep and Multifactorlal Process[Pelayo Correa] (One cassette)

D CAN 246 Eleventh Cornelius P. Rhoads Memorial$1 1.50 Award Lecture: Analysis of Protein

Function in Vivo by Targeted GeneDisruption [Elizabeth J. Robertson](One cassette)

D CAN 248 Symposium 10: The p53 Tumor Suppressor$23.00 Gene (Two cassettes)

D CAN 249 Symposium 11: Breast Cancer$23.00 (Two cassettes)

D CAN 250 Symposium 12: Gene Expression and$34.50 Chromatin Structure (Three cassettes)

D CAN 251 Minisymposium Biology 15: Angiogenesis$34.50 (Three cassettes)

D CAN 252 Minisymposium Preclinical$34.50 Pharmacology/Experimental Therapeutics

33: Antisense (Three cassettes)D CAN 253 Minisymposium Molecular Biology/Virology

$23.00 11: Tumor Suppressor Genes I(Two cassettes)

D CAN 254 Minisymposium Clinical Investigations 19:$23.00 Molecular Biology of Human Cancer II

(Two cassettes)D CAN 255 Symposium 13: Molecular Mechanisms In

$23.00 Carcinogenesis (Two cassettes)D CAN 256 Symposiu n 14: Molecular Approaches to

$23.00 Diagnosis and Patient Evaluation

CONTINUED.

D CAN 257 Minisymposium Immunology 13: Cytokine$34.50 Modulation of Tumor Growth

(Three cassettes)D CAN 258 Minisymposium Preclinical

$34.50 Pharmacology/Experimental Therapeutic«35: Liposomes in Drug Delivery(Three cassettes)

D CAN 259 Minisymposium Carcinogenesis 22:$34.50 Mutational Specificity (Three cassettes)

D CAN 260 Minisymposium Biology 16: Signal$34.50 Transduction (Three cassettes)

28th ANNUAL MEETING OF THE AMERICANSOCIETY OF CLINICAL ONCOLOGY

MAY 17-19, 1992

O CO 201 (S1) Pain Control in Patients With$11.50 Cancer (One cassette)

D CO 202 (S2) Ovarian Cancer$11.50 (One cassette)

O CO 203 (S3) Lung Cancer$11.50 (One cassette)

D CO 204 (S4) Molecular Biology$11.50 (One cassette)

D CO 205 (S5) Clinical Pharmacology for the$23.00 Non-Pharmacologist (Two cassettes)

D CO 206 (S6) Promising New Drugs$11.50 (One cassette)

D CO 207 (S7) Interpreting the Results of$11.50 Clinical Trials: What do the Data Mean

to Me? (One cassette)D CO 208 (S8) Futuristic Therapy of Breast

$11.50 Cancer (One cassette)D CO 209 (S9) Hodgkin's Disease: An Update

$11.50 (One cassette)D CO 210 (S10) Myelodysplasia Syndromes in

$11.50 Pediatrie and Adult Patients(One cassette)

D CO 211 (S11) Organ Preservation in$ 11.50 Multimodallty Solid Tumor Therapy

(One cassette)D CO 212 (SI2) New Aspects in Early Stage

$11.50 Prostate Cancer (One cassette)D CO 213 (SITI ) Pediatrie Brain Tumors

$11.50 (One cassette)D CO 214 (SIT2) Breast Cancer Prevention With

$11.50 Diet and Tamoxifen (One cassette)

D CO 215 (SIT3) Cancer in Older Persons$11.50 (One cassette)

D CO 216 (SIT4) Acceptance and Implementation$11.50 of New Therapy (One cassette)

D CO 217 Breast Cancer: Adjuvant Therapies$34.50 (Three cassettes)

D CO 218 Non-Small Cell Lung Cancer/Head and$34.50 Neck Tumors (Three cassettes)

D CO 219 Adult Leukemia$34.50 (Three cassettes)

D CO 220 Clinical Pharmacology$34.50 (Three cassettes)

D CO 221 Pediatrie Solid Tumors$34.50 (Three cassettes)

D CO 222 Presidential Address and Awards$11.50 Ceremony [Martin D. Abeloff, MD] (One Cassette)

D CO 223 Twenty-Third Annual David A. Karnofsky$11.50 Memorial Lecture: Ode to Methotrexate

[Joseph Berlino, MD] (One Cassette)D CO 224 Plenary Session

$23.00 (Two Cassettes)D CO 225 Breast Cancer: Advanced

$34.50 (Three Cassettes)D CO 226 Gastrointestinal Tract Cancer

$34.50 (Three Cassettes)D CO 227 Genitourinary Tract Cancer

$34.50 (Three Cassettes)D CO 228 Tumor Immunology

$34.50 (Three Cassettes)D CO 229 Pediatrie Leukemia and Lymphoma

$34.50 (Three Cassettes)D CO 230 Small Cell Lung Cancer/Central

$34.50 Nervous System Tumors (Three Cassettes)D CO 231 Adult Lymphoma

$34.50 (Three Cassettes)D CO 232 Melanoma/Sarcoma

$34.50 (Three Cassettes)D CO 233 Gynecological Tumors

$34.50 (Three Cassettes)O CO 234 Epidemiology/Cancer Prevention and

$34.50 Control (Three Cassettes)D CO 235 Cancer Biology and Molecular Genetics

$23.00 (Two Cassettes)D CO 236 Lung Cancer (Poster Discussion)

$11.50 (One Cassette)D CO 237 Psychosocial Aspects

$11.50 (One Cassette)

Special Offer:Buy all 16 Symposia & Special Interest Topic Sessions

at a 10% Savings —¿�$165.00 (Regular Price $184.00)

DISCOUNTS:1-56-1112-2425-4849 or more tapes

..$11.50 Each

. .5% Discount

. .10% Discount

..15% Discount

. .20% Discount

HOW TO ORDER: Check desired cassettes. Fill in information below. Send to Teach'em, Inc., 160 E. Illinois St.,Chicago, IL 60611. Call: (312)467-0424 or Toll-Free: 1-800-225-3775. Fax:1-312-467-9271.

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Foreign Country: Add $2 per tape outside the U.S. $_

Shipping and Handling $_ 4.00

TOTAL (in U.S. funds) $

D Check enclosed payable to Teach'em, Inc.

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Keep upwith the latest developments in

CanœrRoseareTheOfficial Journal of the

American Association tor Cancer Research

Cancer Research

PP 1-207ISSNCO» '--: -

Carlo M. Croce, M.D., Editor-in-Chief

Subscribe to Cancer Research—the leading citation source of original studies in cancer researchand cancer-related biomedicai science. Issuedsemimonthly, Cancer Research publishes 7,000pages of important research each year, includingthe following regular features:•¿�The most up-to-date articles in basic researchand clinical and epidemiological investigations byauthors from the United States and more than 20countries•¿�Perspectives in Cancer Research, in whichleading investigators explore contemporary andat times controversial topics•¿�Advances in Briet, a rapid communication category for short but definitive, highly significant reports•¿�Supplemental issues developed from symposiaon relevant subjects•¿�Proceedings oíthe American Association forCancer Research, a special annual issuethat offers stimulating new research ideas in abstractform

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CancerResearchThe MostHighly CitedJournalIn Its Field

AMERICAN ASSOCIATION FOR CANCER RESEARCH84th Annual Meeting

Michael B. Sporn, Program ChairpersonOrange County Civic Center, Orlando, FL

May 19-22, 1993

Major Sessions: Titles and Chairpersons

Predicting the Impact of Molecular Biology onCancer Therapy in the 21st Century •¿�Joint AACR/ASCO Session - Stephen H. Friend

Transgenic Mice as Models for CancerPathogenesis Owen N. Witte

From Bench to Clinic: Concepts in the Designand Targeting of New ChemotherapeuticAgents Bruce A. Chabner

Tumor Invasion, Angiogenesis, and MetastasisRobert S. Kerbel

Mechanisms of Action of ChemopreventiveAgents: Basic Science and ClinicalApplications Martin Lipkin and Anita B.Roberts

Molecular Mechanisms of Drug ResistanceJune L. Biedler

Advances in Molecular Epidemiology of HumanCancer Curtis C. Harris

Cytokines in the Immunomodulation of CancerElizabeth A. Grimm

The Biology and Therapeutic Application ofNormal Hematopoietic Stem Cells MalcolmA. S. Moore

The Restoration of Normal Differentiation andGrowth to Preneoplastic and NeoplasticCells: Strategies for Differentiation TherapyWaun Ki Hong

Nitric Oxide and Superoxide: EndogenousMediators of DNA Damage Steven R.Tannenbaum

Biology and Pathogenesis of Prostate CancerMaarten C. Bosland

Vitamin D and Cancer Michael B. Sporn

Mesenchymal-Epithelial Interactions withNormal and Neoplastic Epithelial CellsGerald R. Cunha

Proteases in Carcinogenesis and TumorProgression Lynn M. Matrisian

Strategies for Utilization of Antisolisi-Molecules or Ribozymes as SpecificAnticancer Agents Jack S. Cohen

Biology and Genetics of Human PreneoplasticLesions Walter N. Hittelman

Human DNA and Protein Adduct Dosimetry:Regina M. Santella

Biology and Treatment of Pediatrie CancerRichard J. O'Reilly

Latest Advances in Tumor Suppressor GenesEdward E. Harlow

Immunologie Approaches to Targeted TherapyIra Pastan

Molecular Basis for the Modulation ofRadiation Sensitivity W. Gillies McKenna

Gene Rearrangements in Human CancerStanley J. Korsmeyer

Protein Phosphatases in CarcinogenesisClaude B. Klee

Protein Kinase C: Modulator of the CancerPhenotype and Target for ChemotherapyPeter M. Blumberg

The EGF and FGF Receptor Superfamilies:Recent Advances in Ligands, Receptors, andSignal Transduction Andrew Baird andMichael Klagsbrun

Workshop: Clinical Research MethodologyErigid G. Leventhal and Steven Piantadosi

Workshop: Embryonic Stem Cells and GeneKnockouts Thomas C. Doetschman

Further Information: AACR Office •¿�Public LedgerBuilding •¿�620 Chestnut Street •¿�Suite 816 •¿�Philadelphia, PA 19106-3483TELEPHONE (215) 440-9300 •¿�FAX (215) 440-9313