Rang Aandeelhouders: Laatste Datum

Laatst bijgewerkt dd 13 nov 2017 melding Melding Cum. Vorige

bij (o.a.) % % 50.895.778 Melding

1 Gilead Biopharmaceutics Ireland G 1-3-2016 13,28 13,28 6.760.701

2 Van Herk Investments BV G 15-2-2017 21,03 7,75 3.943.150

3 Fidelity Management & Research FMR LLC W 13-11-2017 26,54 5,51 2.802.331 3.558.920

4 Sands Capital Management , LLC F 14-8-2017 30,74 4,20 2.138.491

5 Federated Investors Inc. /PA W 13-11-2017 33,39 2,65 1.349.600 1.364.600

6 OFI Global Asset Man, Inc. (=Oppenheimer) MI 30-9-2017 35,25 1,86 945.188

7 Vanguard Group Inc MI 30-9-2017 37,06 1,81 922.898

8 VA College America Smallcap World 529E/Cap Res &MCMF & MI 30-9-2017 38,64 1,58 803.989

9 Federated Equity Mgmt Co. of Pennsylvania MI 30-9-2017 39,86 1,22 621.800

10 EcoR1 Capital LLC F 30-6-2017 41,00 1,14 578.505

11 Insiders (Glpg Directie & Raad van Bestuur) G 21-9-2017 42,12 1,12 570.635

12 InverCaixa Gestión SGIIC MI 30-9-2017 42,88 0,76 388.081

13 DFA Dimensional Fund Advisors LP MI 30-9-2017 43,64 0,76 384.846

14 Wellington Management Group LLP W 13-11-2017 44,31 0,67 342.654 396.721

15 BlackRock Fund Advisors MI 8-11-2017 44,94 0,62 318.057

16 NN Investment Partners BV MI 31-8-2017 45,54 0,61 309.408

17 Cormorant Asset Management, LLC F 14-8-2017 46,13 0,59 300.000

18 Orbimed advisors LLC F 14-8-2017 46,69 0,56 283.500

19 Vanguard Health Care Fund GU & MI 30-9-2017 47,25 0,56 282.879

20 Gilder Gagnon Howe & Co LLC YI 30-6-2017 47,80 0,55 279.777

21 Renaissance Technologies LLC W 13-11-2017 48,32 0,52 266.500 465.300

22 Baker Brothers Advisors LP F 14-8-2017 48,83 0,51 259.894

23 Capfi Delen Asset Management S.A. MI 30-9-2017 49,33 0,50 254.599

24 J.P. Morgan Investment Management Inc. MI 30-9-2017 49,82 0,48 246.469

25 Goldman Sachs Asset Management LP MI 30-6-2017 50,29 0,48 241.802

26 Oberweis Asset Management Inc. MI 30-6-2017 50,74 0,45 230.000

27 Perceptive Advisors LLC F 14-8-2017 51,19 0,44 226.405

28 Rock Springs Capital Management LP F 14-8-2017 51,62 0,44 221.500

29 Old Westbury Large Cap Strategies MF ADR 31-7-2017 52,05 0,43 220.000

30 Edmond de Rothschild Asset Man (Fr) MI 30-9-2017 52,48 0,42 215.000

31 Goldman Sachs Group Inc. F 14-8-2017 52,87 0,40 202.173

32 De Grote Voskuil Capital BV MI 31-7-2017 53,27 0,39 200.000

33 Deutsche Asset & Wealth Man. Inv. GmbH MI 2-11-2017 53,61 0,34 173.670

34 Deutsche Bank AG F 11-8-2017 53,94 0,33 169.395

35 Close Finsbury Asset Management Limited MI ADR 31-7-2017 54,27 0,33 169.000

36 iShares MSCI EAFE Small-Cap MF 8-11-2017 54,59 0,32 161.937

37 BlackRock Advisors (UK) Limited MI 8-11-2017 54,91 0,32 160.369

38 Morgan Stanley F 11-8-2017 55,21 0,31 155.767

39 BlackRock Inc. F 10-8-2017 55,50 0,29 148.300

40 Goldman Sachs Asset Management LP MI ADR 30-6-2017 55,79 0,29 147.905

41 Fortis Investments (BE) MI 30-9-2017 56,08 0,29 145.184

42 Sands Capital Global Growth Inst MF ADR 31-7-2017 56,36 0,28 144.500

43 Hartford Funds Management Company, LLC MI 30-9-2017 56,64 0,27 138.337

44 Natixis Asset Management MI 30-9-2017 56,90 0,26 133.214

45 Deerfield Management Co W 13-11-2017 57,15 0,26 130.000 187.501

46 Dreyfus Int Small Cap A MF & MI 30-9-2017 57,40 0,25 127.054

47 BlackRock Asset Management (DEU) AG MI 31-10-2017 57,64 0,24 119.836

48 Jane Street Group, LLC F 14-8-2017 57,87 0,23 119.139

49 Goldman Sachs Small/Mid Cap Growth A MF ADR 30-9-2017 58,09 0,22 110.644

50 Peregrine Capital Management LLC F 25-10-2017 58,30 0,21 106.594

51 iShares Core MSCI EAFE MF 8-11-2017 58,50 0,20 103.526

52 Morgan Stanley & Co Inc. MI ADR 30-6-2017 58,71 0,20 103.422

53 Rhenman Partners Asset Management AB MI 31-7-2017 58,90 0,19 97.000

54 Hartford Healthcare A MF 30-9-2017 59,09 0,19 96.323

55 KBC Asset Management N.V. (vh Eperon Asset Mngt) MI 30-6-2017 59,27 0,19 95.801

56 Williams Jones & Ass. LLC F 14-8-2017 59,45 0,18 91.317

57 Threadneedle Asset Management Limited MI 31-8-2017 59,63 0,18 89.212

58 AQR Long-Short Equity I MF 30-6-2017 59,79 0,16 82.421

59 BlackRock Health Sciences Opps Inv A /Blackrock AdvisorsMI & MF ADR30-9-2017 59,94 0,15 76.400

60 Petercam S.A. MI 31-7-2017 60,09 0,15 75.721

61 Eaton Vance Worldwide Health Sci A MF 31-8-2017 60,23 0,14 71.363

62 Brookside Cap M/ Bain Capital Public Equity Man. LLC F 14-8-2017 60,37 0,14 71.136

63 Her Majesty the Queen in Right of prov Alberta etc. F 11-8-2017 60,51 0,14 70.000

64 Clough Capital Partners L.P. F 14-8-2017 60,64 0,14 69.853

65 Hartford Small Company HLS IA MF ADR 30-9-2017 60,78 0,13 68.119

66 Wells Fargo Small Company Growth Admin MF ADR 30-9-2017 60,91 0,13 67.405

67 Tekla Life Sciences Investors MF ADR 30-6-2017 61,04 0,13 65.000

68 Employees Retirement system of Texas F 13-11-2017 61,14 0,11 54.000

69 NN Investment Partners Belgium MI 30-6-2017 61,25 0,10 53.000

70 American Century Intl Discovery Inv MF 30-9-2017 61,35 0,10 52.700

71 Morgan Stanley Smith Barney LLC MI ADR 30-6-2017 61,45 0,10 52.351

72 Eventide Asset Management F 14-8-2017 61,56 0,10 52.000

73 Hartford Small Company A MF ADR 30-9-2017 61,66 0,10 51.119

74 ALPS Medical Breakthroughs ETF MF ADR 31-10-2017 61,76 0,10 50.118

75 Alps Advisors Inc W 3-11-2017 61,85 0,10 50.045

76 J Hancock Seaport A MF 30-9-2017 61,95 0,10 48.639

77 Dorsey Wright & Associates W 6-11-2017 62,04 0,10 48.357

78 Banque Degroof MI 30-6-2017 62,14 0,09 46.500

79 JHVIT Small Cap Growth NAV MF ADR 30-9-2017 62,22 0,09 44.355

80 Arctic Fund Management MI 30-9-2017 62,31 0,08 42.461

81 Goldman Sachs Intl Eq Insights A MF 30-4-2017 62,39 0,08 42.037

82 Millennium Management LLC F 14-8-2017 62,47 0,08 41.458

83 Bank of New York (BNY) Mellon corp W 6-11-2017 62,55 0,08 40.813

84 Dafna Capital management LLC F 14-8-2017 62,63 0,08 38.609

85 Platinum Asset Management MI 31-8-2017 62,70 0,07 36.800

86 JPMCB Global Focus Fund MF 30-6-2017 62,77 0,07 35.189

87 AdvisorShares WCM/BNY MlnFcsd GR ADR ETF MI & MF ADR12-11-2017 62,84 0,07 34.478

88 Saint Olive Gestion MI 30-9-2017 62,90 0,06 32.500

89 Pohjola Asset Management Ltd. MI 31-8-2017 62,96 0,06 30.000

90 JPMorgan Chase Bank W 9-11-2017 63,02 0,06 29.929

91 Credit Suisse AG / First Boston (CSFB) F 14-8-2017 63,07 0,06 28.000

92 La Banque Postale Asset Management MI 31-8-2017 63,13 0,05 27.000

93 CREF (College Retirement Equities Fund) Stock R1 MF 30-9-2017 63,18 0,05 26.661

94 Teachers Advisors Inc MI 30-9-2017 63,23 0,05 26.652

95 JHFunds2 Small Cap Growth 1 MF ADR 31-8-2017 63,28 0,05 26.343

96 Carrera Asset Management Co.,Ltd. MI ADR 17-4-2017 63,33 0,05 25.000

97 Lyxor International Asset Management MI 30-9-2017 63,38 0,05 24.713

98 Eurizon Capital SGR SpA MI 31-7-2017 63,43 0,05 24.700

99 American Century NT Intl Sm-Md Cp Instl MF 30-9-2017 63,48 0,05 24.599

100 Habbel, Pohlig & Partner Gmbh MI 31-8-2017 63,52 0,05 24.207

101 Puilaetco Dewaay Private Bankers SA MI 31-10-2017 63,57 0,04 22.300

102 Hartford Healthcare HLS IA MF 30-9-2017 63,61 0,04 22.056

103 Clough Global Equity MF ADR 30-9-2017 63,65 0,04 21.500

104 Nationwide Fund Advisors MI 30-9-2017 63,69 0,04 21.163

105 NVIT Multi-Manager International Gr Y MF 30-9-2017 63,74 0,04 21.163

106 Weiss Multi-Strategy Advisers LLC F 14-8-2017 63,78 0,04 20.000

107 Hartford International Small Company A MF 30-9-2017 63,82 0,04 19.952

108 KBL European Private Bankers MI 30-6-2017 63,85 0,04 19.651

109 USAA Science & Technology MF 30-9-2017 63,89 0,04 19.452

110 Tekla Capital Management LLC W 13-11-2017 63,93 0,04 19.000

111 Ishares MSCI Belgium Capped MF 9-11-2017 63,97 0,04 18.999

112 Touchstone Sustainability & Imp Eq A/ Adv MI & MF 30-9-2017 64,00 0,04 18.840

113 Atika Capital Management LLC F 14-8-2017 64,04 0,04 18.000

114 Connor Clark & Lunn Financial Group MI 31-10-2017 64,07 0,04 17.964

115 Deutsche Health and Wellness S MF ADR 30-9-2017 64,11 0,03 17.774

116 HBM Partners AG MI ADR 30-6-2017 64,14 0,03 17.500

117 Alliance Bernstein L.P. W 13-11-2017 64,18 0,03 17.410

118 HBK Investments L P F 14-8-2017 64,21 0,03 17.300

119 FNY Partners Fund LP W 9-11-2017 64,25 0,03 17.200

120 Allianz Invest KAG mbH MI 30-6-2017 64,28 0,03 17.000

121 AQR Multi-Strategy Alternative I MF ADR 30-9-2017 64,31 0,03 16.424

122 Credit Suisse AG MI ADR 30-9-2017 64,34 0,03 15.500

123 Guidestone Capital Management MF & MI 30-9-2017 64,37 0,03 15.222

124 Bank Of New York CO Inc. MI ADR 30-6-2017 64,40 0,03 15.079

125 American Century International Opps Inv MF 30-9-2017 64,43 0,03 15.025

126 BlackRock MSCI ACWI ex-U.S. IMI Index T MF 30-9-2017 64,46 0,03 14.823

127 Citadel Advisors LLC W 9-11-2017 64,49 0,03 14.179

128 Axa Investments Managers Paris MI 30-9-2017 64,52 0,03 14.000

129 Financière Arbevel MI 31-8-2017 64,54 0,03 13.192

130 Airain LTD F 8-8-2017 64,57 0,02 12.204

131 Eqis Capital Management, Inc F 3-10-2017 64,59 0,02 12.192

132 MML Ser Inv Fund Small Cap Gr Eq Init MF&MI&MF ADR30-9-2017 64,61 0,02 11.564

133 Driehaus Capital Management LLC F 14-8-2017 64,63 0,02 10.803

134 P.A.W. Capital Corp. W 23-10-2017 64,65 0,02 10.000

135 Sal. Oppenheim jr. & Cie. AG & Co. KGaA MI ADR 31-3-2017 64,67 0,02 10.000

136 Cubist Systematic Strategies, LLC F 14-8-2017 64,69 0,02 9.200

137 Macquarie Group Ltd W 8-11-2017 64,71 0,02 8.637

138 Optimum Small-Mid Cap Growth A MF ADR 30-9-2017 64,72 0,02 8.632

139 Swiss Life Asset Management (France) MI 31-7-2017 64,74 0,01 7.367

140 Transamerica Global Equity A MF 30-9-2017 64,75 0,01 7.054

141 Charlemagne Capital (UK) Ltd MI 31-3-2017 64,77 0,01 6.597

142 Landscape Capital Management LLC F 14-8-2017 64,78 0,01 6.589

143 BlackRock MSCI EAFE® Small Cap Equity Index FMF 30-9-2017 64,79 0,01 6.406

144 Castleark Management LLC F 15-8-2017 64,80 0,01 6.075

145 Susquehanna Int. Group. LLP F 15-8-2017 64,81 0,01 5.754

146 Rockefeller Equity Allocation Instl MI & MF 30-9-2017 64,83 0,01 5.736

147 MassMutual Premier Small Cap Opps A MF 30-9-2017 64,84 0,01 5.673

148 EntrepreneurShares Global Instl /Weston Cap Advisors,LLCMI & MF 30-9-2017 64,85 0,01 5.624

149 VALIC Company I Small-Mid Growth MF ADR 31-8-2017 64,86 0,01 5.459

150 Blackrock MI 30-6-2017 64,87 0,01 5.313

151 Bank of America Corp /DE/ F 14-8-2017 64,88 0,01 5.291

152 Bankinter Gestión de Activos SGIIC MI 31-3-2017 64,89 0,01 5.102

153 Geode Capital Managment LLC F 14-8-2017 64,90 0,01 4.578

154 BI Asset Mgmt Fondsmaeglerselskab A/S MI 30-9-2017 64,91 0,01 4.402

155 SPGP MI 31-3-2017 64,92 0,01 4.298

156 BlackRock Health Sciences MF ADR 31-3-2017 64,92 0,01 4.200

157 Royal Bank of Canada F 14-8-2017 64,93 0,01 4.170

158 Wells Fargo Funds Management LLC MI 30-9-2017 64,94 0,01 4.159

159 Aperio Group LLC F 24-10-2017 64,95 0,01 4.159

160 Us Bancorp \DE\ (= FAF Advisors Inc.) W 13-11-2017 64,96 0,01 3.842 27.731

161 Sit Int. Growth / Sit Investment Associates Inc MI & MF 30-9-2017 64,96 0,01 3.725

162 OFI Asset Management MI 31-5-2017 64,97 0,01 3.629

163 Cookson Peirce &Co Inc W 13-11-2017 64,98 0,01 3.495 3.045

164 SPDR® EURO STOXX Small Cap ETF MF 10-11-2017 64,98 0,01 3.448

165 The Boston International Small Cap CF MF 31-10-2017 64,99 0,01 3.118

166 Virtu KCG Holdings LLC F 11-8-2017 65,00 0,01 3.096

167 Penn Series SMID Cap Growth/Penn Mutual Ass. Man. MI & MF ADR30-9-2017 65,00 0,01 3.064

168 World Asset Management Inc. W 3-11-2017 65,01 0,01 2.983

169 Atria Investments LLC W 12-10-2017 65,01 0,01 2.933

170 Voya Multi-Manager International Sm Cp A MF 30-9-2017 65,02 0,01 2.900

171 Advisor Group, Inc W 6-11-2017 65,03 0,01 2.829

172 Bank of Montreal Canada F 16-10-2017 65,03 0,01 2.828

173 American Century Non-U.S. Small-Mid Cap MF 31-3-2017 65,04 0,01 2.823

174 Arrowstreet Capital, Limited Partnership F 15-8-2017 65,04 0,01 2.800

175 Comerica Bank W 6-11-2017 65,05 0,01 2.730

176 Ariel International I MF 30-9-2017 65,05 0,01 2.646

177 UBS Global Allocation P MF 30-6-2017 65,06 0,01 2.589

178 Financière de Champlain MI 31-7-2017 65,06 0,01 2.578

179 Interselec NV MI ADR 31-12-2016 65,07 0,00 2.500

180 UBS Group AG F 14-8-2017 65,07 0,00 2.377

181 Dynamic Technology Lab Private Ltd W 8-11-2017 65,08 0,00 2.144

182 Great-West Multi-Manager Sm Cp Gr Instl MF ADR 30-6-2017 65,08 0,00 2.138

183 BNY Mellon Investment Management MI ADR 30-6-2017 65,08 0,00 2.015

184 TETON Westwood Mighty Mites AAA MF ADR 30-6-2017 65,09 0,00 2.000

185 Russell Select International Equity Y MF ADR 30-9-2017 65,09 0,00 1.967

186 American Century Strat Allc: Mod Inv MF 30-9-2017 65,10 0,00 1.847

187 Envestnet Asset Management Inc W 13-11-2017 65,10 0,00 1.742 679

188 Advisors Preferred, LLC F 31-10-2017 65,10 0,00 1.029

189 PINK Capital MI 28-2-2017 65,10 0,00 810

190 Wells Fargo & Company/MN W 10-8-2017 65,10 0,00 734

191 Dreyfus/The Boston Co Small Cap Gr I / Dreyfus Corp MI & MF ADR30-9-2017 65,11 0,00 706

192 Schwab International Small-Cap Eq ETF™ MF 9-11-2017 65,11 0,00 692

193 Cutler group LP W 17-10-2017 65,11 0,00 600

194 Springbok Capital Mngt LLC (= Prelude Cap Mngt?) F 14-8-2017 65,11 0,00 468

195 PMC Diversified Equity MF ADR 30-9-2017 65,11 0,00 443

196 Quantbot Technologies LP W 7-11-2017 65,11 0,00 148

197 Oppenheimer Asset Man. Inc F 9-8-2017 65,11 0,00 47

198 Next Financial Group Inc HC 8-11-2017 65,11 0,00 3

199 Ascend Capital, LLC W 13-11-2017 65,11 0,00 0 73.964

200 Graticule Asia Macro Advisirs LLC W 13-11-2017 65,11 0,00 0 41.818

201 Hudson Bay Capital Management LP W 13-11-2017 65,11 0,00 0 20.000

202 Northern Trust Corp. W 13-11-2017 65,11 0,00 0 18.480

203 Marshall Wace North America LP W 13-11-2017 65,11 0,00 0 17.011

204 Pacad Investment LTD W 13-11-2017 65,11 0,00 0 2.200Subtotaal 65,11 33.138.401

Overige 34,89 17.757.377Totaal 100,00 50.895.778