2007 Gastroreg Lecture

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    GASTROINTESTINAL RADIOLOGY

    1. Liver Lesions Haemangioma and HCC

    2. CT Colonography

    3. Small bowel - CT, MRI or fluoroscopy?

    4. Rectal tumor MRI staging

    5. Anal fistula MRI imaging

    Topics to be covered

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    Liver Haemangioma (US)

    Atypical

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    Liver Haemangioma CT

    A) Pre-contrast

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    B) Arterial phase

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    C) Portal venous phase

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    D) Delayed phase

    CT we will not do delayed phase unless haemangioma suspected.

    Please specify ? haemangioma on request form.

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    Haemangioma Summary

    Common- often incidental

    US Echogenic -no halo. No colour flow.

    Aytpical hypo-echoic in fatty liver

    - mixed echotexture

    CT C- low densityC+ peripheral vessels (uneven)

    C+ PV /delay progressive fill-in

    Small haemangioma fill in immediately andcannot be distinguished from metastates.

    MRI features similar to CT post Gadolinium

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    CT -HCC

    pre contrast

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    Arterial enhancement

    (central and early)

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    Washout on portal venous

    indicates fast flow

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    HCC Summary

    US - usually heterogeneous Usually HepB +ve withraised alpha FP

    CT C- low density

    C+A central early contrast (high flow rate)C+PV washout cf with liver

    may have a capsule

    MR intracellular fat on T1 out of phase- similar perfusion characteristics to CT

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    MRI IMAGES of LIVER

    Look at CSF first to tell if T1 or T2

    T1-in/out.

    T1 are grey. Fluid is dark. Black outline

    T2-incl HASTE.

    More definition. Fluid is bright.

    Gadolinium always with T1

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    Fatty liver with sparing

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    Same pt - out of phase T1 MRI

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    Same patient - CT non-contrast

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    CT COLONOGRAPHY

    Dissection

    Strip, anus

    to caecum

    Endoluminal(for fun only)

    800/40 windowAxial to loops

    OrientationOverview

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    Advantages / disadvantages

    Sensitivity and specificity is of the order of 90 %

    for 10 mm polyps. Easy, quick and well tolerated.

    Beats barium enema hands down.

    Safer than optical colonoscopy Approx. half the price of optical colonoscopy

    No intervention possible as in optical Cy

    At present for Ba enema indications, but is likely

    to be used for screening in future. Radiology manpower training required.

    Radiation dose equivalent to Ba Enema

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    Incidence of Colonic Perforation at CT Colonography: Review ofExisting Data and Implications for Screening Asymptomatic AdultSource: International Working Group on Virtual Colonoscopy

    Total VC studies considered 21,923

    Symptomatic Perforation Rates for VC* 0.005%

    Total Perforation Rates for VC 0.009%

    Perforation Rates for Conventional Colonoscopy 0.1-0.2%

    Pickhardt 2007

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    CTC vs Optical Colonoscopy

    CTC for average risk and Fam Hx pts.

    > 50 yrs (radiation)

    Contraindicated if inflammatory bowel or on steroids(risk of perforation as inflation is done blind as

    opposed to Ba enema).

    Optical Colonoscopy if biopsy or polypectomy probneeded

    All polyposis syndromes High risk

    Inflammatory Bowel Disease

    Consider Is intervention likely to be needed? (cf MRCP vs ERCP)

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    Overview of CT colonography?

    Process Currently Future

    CLEANSE -Tagging -Subtraction

    DISTEND -Air -CO2

    COMPUTE -Workstation -new programs

    VIEW -Time - CAD

    REPORT -Issues

    P d i

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    Prep and tagging

    Slide courtesy Dr Helen Moore

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    Longer tube and patient can apply air

    themselves

    Slide courtes Dr Helen Moore

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    Lateral topogram

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    Philips workstation layout

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    Incomplete air column -Excess fluid

    Supine Prone

    Can rotate ima e volume to view as a Ba enema in 3D

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    Diverticular disease

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    4 mm Polyp

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    Ileo-caecal valve

    Residual

    tagging

    Arrow points

    To caecum

    Caecal

    pole

    Dirty Caecum

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    Dirty Caecum-not fully open on supine or prone views

    54 yr

    Recomm optical

    colonoscopy

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    The dirty caecum

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    Complex Folds at flexures

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    Radiation Barium enema 6 8 mSv

    CTC estimate of 7.6 mSv with low mAs.Increased noise, but high resolution

    improves definition of small polyps

    Thin slice, limit tube current

    Background radiation is 2.4 MSv/year

    The worldwide average background dose for a human being is about 2.4

    millisievert (mSv) per year.[1] This exposure is mostly from cosmic radiation andnatural isotopes in the Earth. This is far greater than human-caused background

    radiation exposure, which in the year 2000 amounted to an average of about

    0.01 mSv per year from historical nuclear weapons testing, nuclear power

    accidents and nuclear industry operation combined,[2] and is greater than the

    average exposure from medical tests, which ranges from 0.04 to 1 mSv per

    year. Source Wikipedia.

    http://en.wikipedia.org/wiki/Absorbed_dosehttp://en.wikipedia.org/wiki/Sieverthttp://en.wikipedia.org/wiki/Sieverthttp://en.wikipedia.org/wiki/Absorbed_dose
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    Small Bowel Imaging

    < 35 yrs MRI for radiation reasons

    However if pre-surgical workupfluoroscopy

    CT Enteroclysis only difference from CT isnegative contrast in bowel. No advantage to

    do if recent normal CT.

    MR Small bowel breath-hold sequences,

    dynamic change between sequences. Good

    soft tissue differentiation. +/- Gadolinium

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    Normal Fluoroscopic Enteroclysis

    Jejunal intubation

    Low density barium

    Pumped in to distend

    Intubation 10 min

    Study 20 min

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    Terminal ileum

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    Skip lesions - Proximal

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    Follow-through

    time-consumingflocculation

    Strictures maybe hidden

    Is superseded

    by other tests

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    Enteroclysis- same patient

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    Intra-luminal mass

    CT Enteroclysis

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    CT Enteroclysis

    Tumor shows up against negative contrast in bowel. Positive contrast could hide it

    Histo- GIST

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    CT ENTEROCLYSIS

    Volumen oral contrast for 45 min pre scan

    IV Maxolon

    IV contrast on table

    CT to include anal canal and with sagittal.

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    CT ENTEROCLYSIS

    Jejunum often thick-walled

    Can evaluate bowel wall due to

    negative contrast in lumen and

    IV contrast in wall.

    Evaluates stomach well also

    Plus standard CT

    Reserved for older patients due

    to radiation dose

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    MRI Small Bowel

    Oral Volumen 30 45 min prior (or Ioscan)

    +/- IM Buscopan for peristaltic movement Good for Crohns patients with multiple studies

    and large radiation dose over time.

    Coronal TRUFI

    Coronal TRUFI fat saturation

    Coronal HASTEAxial HASTE

    Coronal T1

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    MRIENTEROCLYSIS

    TRUFI

    N l HASTE

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    Normal- HASTE sequence

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    Terminal ileum

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    Cutaneous fistula

    Post Gadolinium T1 fat sat

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    Caecum / TI

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    Crohns disease

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    Normal

    FAT SATURATION

    Sag axial and coronal

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    Sag, axial and coronal

    N l l l i l

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    Normal anal canal - sagittal

    Subcutaneous

    External sphincter

    Puborectalis

    Internal sphincter

    N l l l i l t PR

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    Normal anal canal - axial at PR

    mucosa

    Internal

    sphincter

    Fat in inter-

    sphincteric spacePubo-rectalis

    = upper external

    sphincter

    N l l l l

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    Normal anal canal - coronal

    InternalSphincter

    Puborectalis

    External

    Sphincter

    Post Gad fat saturation T1

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    Post Gad fat saturation T1

    Drain in situ

    ANTERIOR

    POSTERIOR

    UC i t

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    UC - mucinous tumour

    UC i t

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    UC - mucinous tumour

    A l l t

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    Anal canal tumour

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