ZET JE SPIEREN IN BIJ KANKER - Oncologie in perspectief · ZET JE SPIEREN IN . BIJ KANKER . MASSA ....
Transcript of ZET JE SPIEREN IN BIJ KANKER - Oncologie in perspectief · ZET JE SPIEREN IN . BIJ KANKER . MASSA ....
Jaap Dronkers
ZET JE SPIEREN IN BIJ KANKER
1 M A S S A
SPIER
Spiermassaverlies
Baracos V, Kazemi-Bajestani SM. Clinical outcomes related to muscle mass in humans with cancer and catabolic illnesses. Int J Biochem Cell Biol. 2013 Oct;45(10):2302-8
Inactiviteit
Kortebein P, et al. Functional impact of 10 days of bed rest in healthy older adults. J Gerontol A Biol Sci Med Sci. 2008 Oct;63(10):1076-81.
jong
oud
Functionele mobiliteit
INACTIVITY
83 % of the measured hospital stay was spent
lying in bed
Brown CJ, Redden DT, Flood KL, Allman RM. The underrecognized epidemic of low mobility during hospitalization of older adults. J Am Geriatr Soc. 2009 Sep;57(9):1660-5.
… have demonstrated that 2 weeks of inactivity (muscle disuse via limb immobilization), or even simply decreased physical activity (reduced step count), can also induce anabolic resistance to amino acid administration or protein ingestion …
Wall BT, Cermak NM, van Loon LJ. Dietary protein considerations to support active aging. Sports Med. 2014 Nov;44 Suppl 2:S185-94.
2–4 hours 16 hours
muscle protein synthesis ↑
2 K R A C H T
SPIER
Percentage of the maximal muscle function
30% 100% 0 % 80% 60%
Dai
ly f
unct
ioni
ng
Indicatie
Dronkers JJ, Preoperative physical fitness in older patients, 2013
100% 0 % 45% 25%
Indicatie
Dronkers JJ, Preoperative physical fitness in older patients, 2013
Dai
ly f
unct
ioni
ng
Percentage of the maximal muscle function
30% 100% 0 %
Frailty
Dronkers JJ, Preoperative physical fitness in older patients, 2013
Dai
ly f
unct
ioni
ng
Percentage of the maximal muscle function
S C R E E N I N G
Santoni G, Angleman S, Welmer AK, Mangialasche F, Marengoni A, Fratiglioni L Age-related variation in health status after age 60. PLoS One. 2015 Mar 3;10(3):e0120077...
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Gezondheid Stimuleer het gebruik van de trap in het algemeen. Vergroot gezondheid en vermindert ziekteverzuim
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Muscle mass (HGS)Respiratory function (RCE)Respiratory function (MIP)Lower leg function (CRT)
ADL (TUG)
Activity level (LAPAQ)
CoughSmoking
COPDHeart diseases
DiabetesMetastatic cancer
Age (> 80)
Odds ratio (p<0.1)
DISCHARGE DESTINATION 10 % nursing home n=169
Dronkers JJ, Chorus AM, van Meeteren NL, Hopman-Rock M. The association of pre-operative physical fitness and physical activity with outcome after scheduled major abdominal surgery. Anaesthesia. 2013;68(1):67-73.
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Muscle mass (HGS)Respiratory function (RCE)Respiratory function (MIP)Lower leg function (CRT)
ADL (TUG)
Activity level (LAPAQ)
CoughSmoking
COPDHeart diseases
DiabetesMetastatic cancer
Age (> 80)
Odds ratio (p<0.1)
MORTALITY
Dronkers JJ, Chorus AM, van Meeteren NL, Hopman-Rock M. The association of pre-operative physical fitness and physical activity with outcome after scheduled major abdominal surgery. Anaesthesia. 2013;68(1):67-73.
Muscle mass (HGS)Respiratory function (RCE)Respiratory function (MIP)Lower leg function (CRT)
ADL (TUG)
Activity level (LAPAQ)
CoughSmoking
COPDHeart diseases
DiabetesMetastatic cancer
Age (> 80)
B-value (p<0.05)Odds ratio (p<0.1)
Muscle mass (HGS)Respiratory function (RCE)Respiratory function (MIP)Lower leg function (CRT)
ADL (TUG)
Activity level (LAPAQ)
CoughSmoking
COPDHeart diseases
DiabetesMetastatic cancer
Age (> 80)
Odds ratio (p<0.1)
Mortality
Discharge destination
Muscle mass (HGS)Respiratory function (RCE)Respiratory function (MIP)Lower leg function (CRT)
ADL (TUG)
Activity level (LAPAQ)
CoughSmoking
COPDHeart diseases
DiabetesMetastatic cancer
Age (> 80)
Odds ratio (p<0.05)
3 A C T I V I T E I T
Fiuza-Luces C, Garatachea N, Berger NA, Lucia A. Exercise is the real polypill. Physiology (Bethesda). 2013 Sep;28(5):330-58.
SPIER
Scand J Med Sci Sports. 2017 Apr 28. Effect of an Acute Exercise Bout on Immediate Post-Exercise Irisin Concentration in Adults: A Meta-Analysis. Fox J, Rioux BV, Goulet EDB, Johanssen NM, Swift DL, Bouchard DR, Loewen H, Sénéchal M.
IRISINE
IRISINE
Zhao J1, Su Z2, Qu C3, Dong Y4. Effects of 12 Weeks Resistance Training on Serum Irisin in Older Male Adults. Front Physiol. 2017 Mar 22;8:171.
Activiteitenniveau en PPC
Dronkers JJ, Lamberts H, Reutelingsperger IM, Naber RH, Dronkers-Landman CM, Veldman A, van Meeteren NL. Preoperative therapeutic programme for elderly patients scheduled for elective abdominal oncological surgery: a randomized controlled pilot study. Clin Rehabil. 2010 Jul;24(7):614-22
Hoe veel moet je bewegen
Front Public Health. 2017 Feb 14;5:19. Physical Activity and Survival among Long-term Cancer Survivor and Non-Cancer Cohorts. Gunnell AS, Joyce S, Tomlin S, Taaffe DR, Cormie P, Newton RU, Joseph D, Spry N, Einarsdóttir K, Galvão DA.
Peter Schnohr, James H. O’Keefe, Jacob L. Marott, Peter Lange, Gorm B. Jensen Dose of Jogging and Long-Term Mortality J Am Coll Cardiol. 2015 Jan 16;65(5)
Duvivier BM, Schaper NC, Hesselink MK, van Kan L, Stienen N, Winkens B, Koster A, Savelberg HH. Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes. Diabetologia. 2016 Dec 1. [Epub ahead of print]
Functioneel bewegen
ZET JE SPIEREN IN BIJ KANKER DANK VOOR UW AANDACHT
Meten spiermassa
Inter- en intrabeoordelingsbetrouwbaarheid van echografie voor het bepalen van spierdikte van de Musculus Rectus Femoris Jelena Čuk
Simpson RJ1, Bosch JA2. Special issue on exercise immunology: current perspectives on aging, health and extreme performance Brain Behav Immun. 2014 Jul;39:1-7.