Addlcinformofcarb - cpb-us-e1.wpmucdn.com › sites.ucsc.edu › dist › 9 › 291 › files...
8
Addlcinformofcarb.ae BrNg a cN OH must be o c N fHzO my NR or stereos Of Br no Il O A 30 carb Br MgBr Whoo i Mg fBr a.co ycozH 3 Hz Ot Br coast E i 0 excess O HAC XX H a H Naut h H E II we
Transcript of Addlcinformofcarb - cpb-us-e1.wpmucdn.com › sites.ucsc.edu › dist › 9 › 291 › files...
Addlcinformofcarb.aeBrNga cN OH
mustbe o c NfHzOmy NRor stereos OfBr no Il OA 30 carb
Br MgBr Whooi Mg
fBr a.co ycozH3 HzOt
Br coast
E i0 excess O
HAC XXH a H Naut h H
E II
we
more BREWGacidic
3NH3
IEE i noo n oacid 1 GlfPBrs Br 4h20 Br
O OHBr µ B Broacidic Br BrHo PBR
IIABr
8Br touts5
Keto o
He BEnd OH
ICy EC Gal
o 05io HFKBr O7rpBr sHffoHneutralBrBr Br G
µ c Acyl Suba B Br
O of't LIl 11
FOH OHBr Br
Gabriel Ti OOH
Sym a LgAHry.BR The
o HOTN source
afoot8 HIMbasic
Br 1 NANI2 LAH 3H2O
HsN coE neutral
s
Wohl Degradation CN
NBL JEN Ac EEN 5H C He B f
WINNIE LGGabriel Synth NV
Azide HIpen Nz t RNHZ
Imine HydrolysisIt t It t Hy
IRI to Pi t Ha R2
Nitrile HydrolysisR CIN Rhoa t NHy
Amide hydrolysisRIENHz 5 RIO t Hy
Wolff Kishner
a.eu EtEo EEmtIEhEketone
amideRacemic red nmix mechFormed when group can
attack top or bottom face of
no PBI Br yztyay.BR
Bry Brtattacks top IboHom
Br fof Br implies Br BrIl HOH OHOH
go 50 mixture ofenantiomers
i i i em
I
IHOT to 0 1
iHt babHclepimers
Hof of NOT enantiomers
Ho f NOT racemic
RED AMIN 0 H
cont ft if gHN
Ho orTojo
bottom HN Har
HEH HN H ofZE.peLego restneutral basic
in IE7 tirHt f
HO l
E i H Tito
G breaks f H
WH 2291 YA o A H
TNR TNR Li yGpkar
NH 12
Arg Antz ska tHN l go Cys
o
H.N fgit.TK Yoopka2
pKazArg 1o_09
TyrpkarlopH 2 7cpHL9 Oncharge
2cpHL7 9 pH 40 I102pA 42 2
few pH 12 3
ID aldose tetr
2 Ho CHI D ketoseHoHt
x o_0
Haight12400 o
Hot.to H5triacylglycerol16y
NIH
phospholipids
